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Showing papers in "Journal of Critical Care in 2005"


Journal ArticleDOI
TL;DR: This tutorial will outline how to prepare SNOSE to preserve allocation concealment in a trial that (a) uses unrestricted (simple) randomization, (b) stratifies randomization on one factor, (c) uses permuted blocks and, and (d) is conducted at more than 1 study site.

485 citations


Journal ArticleDOI
TL;DR: The prevalence of symptoms of anxiety and depression remains high at the end of the ICU stay, whether the patient is well enough to be discharged or is near death.

417 citations


Journal ArticleDOI
TL;DR: The Charlson index should be updated for recent changes in the prognosis of comorbid diseases and introduction of International Statistical Classification of Diseases, 10th Revision coding of discharge abstracts.

357 citations


Journal ArticleDOI
TL;DR: Patients who developed thrombocytopenia in the intensive care unit (ICU) were more likely to die, required longer duration of mechanical ventilation, and were morelikely to require blood product transfusion.

224 citations


Journal ArticleDOI
TL;DR: The wide variations in cost and workload invite efforts to identify patient subgroups most likely to benefit from high-cost treatments and from prevention, particularly targeting severe nosocomial infections.

158 citations


Journal ArticleDOI
TL;DR: Nurses and physicians of Canadian ICUs perceive the need for increased availability of more ICU-directed and ethically trained resources to help them in providing end-of-life care.

148 citations


Journal ArticleDOI
TL;DR: New data suggest that proton pump inhibitors suppress acid production more completely in critically ill patients, but more studies are required to assess their clinical effectiveness and safety for this indication.

142 citations


Journal ArticleDOI
TL;DR: It is feasible to consider using formal consensus in the development of future definitions of acute respiratory distress syndrome, and testing of sensibility, reliability, and validity are needed for this preliminary definition.

129 citations


Journal ArticleDOI
TL;DR: Broad agreement is found on 6 major domains of information that are relevant and important for clinician-patient/family communication when critical illness becomes chronic, as indicated by tracheotomy for prolonged mechanical ventilation.

121 citations


Journal ArticleDOI
TL;DR: In this paper, the authors compared the effect of regional citrate with systemic heparin anticoagulation on filter life span in a Canadian adult regional critical care system using an observational cohort study.

112 citations



Journal ArticleDOI
TL;DR: Venous thromboembolism appears to be an apparently infrequent, but likely underdiagnosed problem, occurring among patients receiving prophylaxis, suggesting the need for increased suspicion among clinicians, renewed efforts at thromboprophylactic, and evaluation of superior prevention strategies.

Journal ArticleDOI
TL;DR: When administered in prophylactic doses to critically ill patients with a wide range of calculated creatinine clearances, there was no evidence of bioaccumulation of dalteparin and it may be an attractive alternative agent for thromboprophylaxis.

Journal ArticleDOI
TL;DR: This pilot study suggests that a multicenter randomized clinical trial comparing LMWH with UFH in critically ill medical-surgical patients is feasible and can improve the design of larger trials and may enhance successful timely completion.

Journal ArticleDOI
TL;DR: Death Rounds provide a unique opportunity for residents to discuss the issues raised in caring for dying patients and should be incorporated into all ICU rotations, according to most residents who participated.

Journal ArticleDOI
TL;DR: Attending physicians, residents, and nurses perceive the recipients of their care, and the system within which they provide this care, to be the major source of barriers to communication regarding end-of-life care, which may impact on the effectiveness of quality-improvement initiatives in end- of- life care.

Journal ArticleDOI
TL;DR: Patients with living wills understand poorly "life-sustaining therapies" and the implications of their advance directives and a significant number of those without living wills have end-of-life wishes that could be addressed by and appear open to the idea of creating advance directives.

Journal ArticleDOI
TL;DR: The history and physical examination for DVT are not useful in detecting lower limb DVT in the ICU, and patients are allocated to low, moderate, and high risk strata for DVt.

Journal ArticleDOI
TL;DR: An assessment of the incidence and prevalence of venous thromboembolic outcome of interest, which includes deep vein thrombosis (DVT) and pulmonary embolism (PE), in medicalsurgical intensive care unit (ICU) patients is based on 3 premises.

Journal ArticleDOI
TL;DR: The use of UG during CP is infrequent despite the demonstrated benefits of this technology, and multiple knowledge and attitudinal barriers to the greater use of EMT during CP must be addressed in the design of an effective UG implementation strategy.

Journal ArticleDOI
TL;DR: The incidence of ARDS is higher than reported a decade ago and is especially elevated in the elderly, especially in elderly patients, and the mortality remains high.

Journal ArticleDOI
TL;DR: Most RNs and RTs were comfortable with decision making and the process of life support withdrawal, but they suggested several ways to improve end-of-life care.

Journal ArticleDOI
TL;DR: Pentaglobin is a promising adjuvant therapy both clinically and economically for treatment of adults with severe sepsis and septic shock and its comparator standard therapy from the hospital perspective in Germany.

Journal ArticleDOI
TL;DR: Analytic hierarchy process, a multiple-attribute decision-making technique, is used in this study to evolve a model for the global performance measurement of intensive care units (ICUs) and to apply that model to compare the services for quality improvement.

Journal ArticleDOI
TL;DR: The Culture, Organization, and Management in Intensive Care questionnaire enables staff and managers to assess the organizational performance of their intensive care unit.

Journal ArticleDOI
TL;DR: A brief history of safety science as it pertains to patient care is reviewed, reviewing remote and recent publications that have guided the maturation of this field that has particular relevance to the complex structure of systems, personnel, and therapies involved in caring for the critically ill.

Journal ArticleDOI
TL;DR: Arterial thromboembolic events are frequent complications of PICU, particularly affecting neonates, and mostly associated with catheters, so studies to determine safe and effective prophylactic and treatment modalities of ATEs in children are required.

Journal ArticleDOI
TL;DR: Community-acquired pneumonia needing mechanical ventilation is not a disease associated with higher mortality, and the main determinants of patient outcome were initial severity of illness and the development of shock and/or acute renal failure.

Journal ArticleDOI
TL;DR: The critical components of sample size calculation, including the selection of a primary outcome, specification of the acceptable types I and II error rates, identification of the minimal clinically important difference, and estimation of the error associated with measuring the primary outcome are reviewed.

Journal ArticleDOI
TL;DR: An overview of the topic is provided and the key components to evaluating and performing research in critical care using administrative data, including how to evaluate the quality of administrative data itself, and also how to evaluates thequality of studies that employ administrative data are reviewed.