Showing papers in "Journal of Critical Care in 2021"

TL;DR: In this article, a systematic review and meta-analysis was performed to determine performance of ROX index as a predictor of high flow nasal cannula (HFNC) failure in COVID-19 patients with acute hypoxemic respiratory failure (AHRF).

TL;DR: This work used rapid review methodology to quickly identify and synthesize studies examining the effect of awake prone positioning on patients with hypoxemic respiratory failure (including those with ARDS and/or COVID-19), and selected studies met the following criteria.

TL;DR: A summary of equipotent ratios for common vasopressors used in clinical practice has been provided and a formula to incorporate into study designs is provided to calculate norepinephrine equivalents (NE) for studies in the intensive care unit.

TL;DR: Sublingual microcirculation in COVID-19 patients showed an altered tissue perfusion, characterized by decreases in the proportion of perfused vessel and flow velocity along with high vascular densities, related to enhanced angiogenesis or hypoxia-induced capillary recruitment.

TL;DR: Wang et al. as mentioned in this paper investigated the severity of burnout and its associated factors among doctors and nurses in ICUs in mainland China and found that people working in the general ICU were most likely to be burnout.

TL;DR: In the aftermath of the 2020 COVID-19 crisis, the prevalence of burnout among intensivists was found to be raised, however this is still low in international comparisons.

TL;DR: Late intubation, Pafi <100, older age, and previous ACE inhibitors use were associated with increased ICU mortality in patients with COVID-19 on mechanical ventilation due to respiratory insufficiency.

TL;DR: This study is the first to explore physicians' moral distress in end-of-life decisions in intensive care via a narrative inquiry approach using case studies, relevant in the Covid 19 pandemic.

TL;DR: A machine learning model can be used to predict future risk of intubation based on clinical data which is routinely collected and available in clinical setting and may facilitate identification of high-risk patients to assist in clinical care.

TL;DR: The decrease in SOFA score associated with survival suggests multi-organ failure involvement during mechanical ventilation in patients with SARS-CoV-2, and surviving women appeared to improve faster than surviving men.

TL;DR: In this paper, a review was conducted to analyze mortality and intubation rates in COVID-19 patients treated with NIV/CPAP, which showed that NIV and CPAP were equally and frequently applied in patients with COVID19 pneumonia, but associated with high mortality.

TL;DR: This study demonstrates that midline catheters are a safe alternative to CVCs, for the safe and efficacious administration of vasopressors for prolonged periods of time.

TL;DR: There is insufficient evidence thatVA-ECMO treatment improves short-term survival of acute PE patients, and low quality evidence suggest that VA-EC MO patients aged ≤60 years or who received SE have higher survival rates.

TL;DR: In this article, the authors conducted a systematic review and meta-analysis to investigate the association between systolic wave (s') obtained with Tissue Doppler Imaging (TDI) and mortality in septic patients.

TL;DR: It is argued that analysing longitudinal data obtained from time-limited trials in intensive care can provide a more robust approach to individual prognostication.

TL;DR: In this paper, the ability of mid-regional proadrenomedullin (MR-proADM) and C-terminal proendothelin-1 (CT-proET-1) to predict 28-day mortality in critically ill patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia was assessed.

TL;DR: In this article, the authors compared the 28-day mortality of 70 patients treated with hemoadsorption adjunctive to renal replacement therapy with the predicted mortality of 73.3%, while the observed mortality was significantly lower.

TL;DR: Patients with LEP are at risk of experiencing suboptimal communication with the healthcare team in the ICU and there are several educational and quality improvement strategies that ICUs and institutions can take to mitigate these issues.

TL;DR: In this article, a systematic review of echocardiographic findings in hospitalized COVID-19 patients was presented. But the authors focused on the negative effects of COVID19 on the cardiovascular system.

TL;DR: Ethical and legal aspects pertinent to triage of this resource-intensive, but potentially life-saving, therapy in the setting of the COVID-19 pandemic are reviewed here.

TL;DR: Metformin use may be associated with reduced risk-adjusted mortality in patients with AKI and T2DM and further randomized controlled trials are needed to clarify this association.

TL;DR: In this article, a case-control study was conducted to determine whether the Macklin effect (a linear collection of air contiguous to the bronchovascular sheath) on baseline CT imaging is an accurate predictor for subsequent pneumomediastinum (PMD)/pneumothorax (PNX) development in invasively ventilated patients with acute respiratory distress syndrome (ARDS).

TL;DR: The ICU Diary is useful to family members as a stress reduction, information management, and communication tool and the design of ICU diary implementations must address system factors to assure family members receive benefits from diary use.

TL;DR: Remote control of life-support systems for COVID-19 patients decreases the frequency of unnecessary interventions and reduces the risk of exposure for both patients and healthcare personnel.

TL;DR: Age remains an important sepsis risk factor, but other conditions correlated more closely with sepsi-associated death than previously thought.

TL;DR: In this paper, the effects of ondansetron use on AKI patient outcomes were investigated using the MIMIC-IV database and the multivariable Cox regression model.

TL;DR: A propensity score overlap weighting analysis was performed to assess the association between spontaneous breathing prone position (SBPP) and intubation in COVID-19 patients with mild to moderate respiratory failure.

TL;DR: Ghana has a significant shortage of critical care beds that are inequitably distributed across the country and a shortfall of intensivists to staff ICUs, and a holistic approach that focuses on the key bottlenecks to quality improvement would be required to improve the capacity and quality ofcritical care delivery.

TL;DR: NMES attenuated the loss of muscle mass, but not of strength, in critically ill patients, and was more likely in patients receiving opioids, patients with a minimal muscle contraction during NMES and patients more prone to lose muscle mass.

TL;DR: A significant association between hypocalcemia, hyponatremia and, of lesser degree, hypomagnesemia on admission and HE or worse outcome in ICH is suggested.