Journal of Dalian Medical University
About: Journal of Dalian Medical University is an academic journal. The journal publishes majorly in the area(s): Genotype & Lung cancer. It has an ISSN identifier of 1671-7295. Over the lifetime, 164 publication(s) have been published receiving 240 citation(s).
Topics: Genotype, Lung cancer, Myocardial infarction, Apoptosis, Survival rate
Papers published on a yearly basis
TL;DR: In this article, a new method for the simultaneous determination of genooposide and genipin in Gardenia jasminoides Eills by reversed-phase high perfomance liquid chromatography was studied.
Abstract: A new method for the simultaneous determination of genooposide and genipin in Gardenia jasminoides Eills by reversed-phase high perfomance liquid chromatography was studied.The method used a YWG-C 18 column,0 05 mol/L di-sodium hydrogen phosphate-methanol(72∶28)as the mobile phase at a flow rate of 1 0 ml/min with detection wavelengty at 240 nm.Retention times and recovery rates for geniposide and genipin were 6 33,9 49 min,and 99 10%,98 28%,respectively.The RSD of the results was 1 05% for geniposide,1 21% for genipin.The method was proved to be simple and reliable.
TL;DR: Transdermal fentanyl combined with Clodine could provide excellent pain relief for the patients with acute herpes zoster and decrease the incidence of complications and PHN.
Abstract: [Objective] To observe the therapeutic effect of transdermal fentanyl in patients with acute Herpes Zoster and the incidence of Postherpetic Neuralgia(PHN).[Methods] Sixty patients were devided randomly into transdermal fentanyl group(F group,n=31) and transdermal fentanyl combined with Clodine group(C group,n=29),both groups were treated with transdermal fentanyl initially(25 μg/ h),a higher dose(50 μg/ h) was given only when the pain of patients was not cont rolled well.Clodine(20 mg,bid,po) was given beside fentanyl patch in C group.The analgesic effect,and the side effects and incidence of PHN were observed.[Results] Compared with F group,highly effective,total effective rate of C group is significantly higher(P0.05);complications and incidence of PHN significantly decreased in C group.[Conclusion] Transdermal fentanyl combined with Clodine could provide excellent pain relief for the patients with acute herpes zoster and decrease the incidence of complications and PHN.
TL;DR: Dauricine can reverse MDR of K562/ADM to some extent and enhance accumulation of adriamycin and daunorubicin, but cause no change in the expression of P-170.
Abstract: Object: To find effective herb medicine having the potency of reversing multidrug resistance (MDR) Method:Dauricine, one kind of herd medicine,has been selected to study its reversal effect to K562/ADM cell line comparing with verapamil as positive control Results:Dauricine can reduce the value of IC50 of adrimycin and incristine against MDR cell line K562/ADM at non-cytotoxic concentration and enhance accumulation of adriamycin and daunorubicin, but cause no change in the expression of P-170Conclusion:Dauricine can reverse MDR of K562/ADM to some extent
TL;DR: In laboratory where it is impossible for HCV RNA measurement by using RT-PCR, HCV-cAg assay in serum will be very useful for the clinical diagnosis of hepatitis C and the detection of HCV.
Abstract: [Objective]To investigate the significance of serum total HCV core antigen(HCV-cAg) in the HCV infection and treatment.[Methods]One hundred and seventy-three serum specimens of HCV infection patients were examined for HCV cAg and anti-HCV antibody with ELISA,for HCV RNA with real-time RT-PCR.[Results]In 173 anti-HCV positive specimens,the positive rate of HCV RNA was 49.7%(86/173) and the positive rate of HCV-cAg was 36.4%(63/173).The positive rate of HCV RNA was higher than that of HCV-cAg(P0.05).In 86 HCV RNA positive specimens,the positive rate of HCV-cAg was 69.8%(60/86),the negative rate was 30.2%(26/86).The control was negative.[Conclusions]In laboratory where it is impossible for HCV RNA measurement by using RT-PCR,HCV-cAg assay in serum will be very useful for the clinical diagnosis of hepatitis C and the detection of HCV.
TL;DR: The RFA is an effective and safe method in the treatment of liver tumor and shows local necrosis and some air bubbles in the lesion post-RFA.
Abstract: [Objective]To investigate the clinical efficacy of radio-frequency ablation in the treatment of liver tumor.[Methods] In all the 215 cases of liver tumor(155 primary hepatic tumor,52 hepatic metastases,1 hepatic adenoma,7 hepatic hemangioma) which were confirmed by biopsy were treated by RFA guiding with CT.All the maximal diameter of lesion were less than 5 cm.And the level of AFP and CEA,the CTA or MRI of liver were all used for investigation(pre and post RFA).[Results]All the malignant liver tumor(207 cases) showed local necrosis and some air bubbles in the lesion post-RFA.And the follow-up study showed 189 cases no tumor manifestation in CT or MRI,also in the level of AFP and CEA.The benign tumor also had the same manifestations in the imaging.18 cases showed local recurrence.[Conclusion] The RFA is an effective and safe method in the treatment of liver tumor.
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