Showing papers in "Journal of Drug Delivery Science and Technology in 2020"

TL;DR: In this article, an ecofriendly, easy, one-step, non-toxic and inexpensive approach is used, where aqueous plant extract acts as a reducing as well as stabilizing agent of Silver Nanoparticles.

TL;DR: Polyvinylpyrrolidone (PVP) is a water-soluble polymer obtained by polymerization of monomer N-vinyl pyrrolide as discussed by the authors, which can be used as a brace component for gene delivery, orthopedic implants, and tissue engineering applications.

TL;DR: In the last one-decade numbers of review and research, articles have been published on niosomes as discussed by the authors, which shows the interest of researchers in Niosomes because of the advantages offered by them over other vesicular carrier systems.

TL;DR: Alginate/chitosan hydrogels loaded with 10% of hesperidin can be used to treat skin injuries in humans according to their morphology, swelling properties, release, weight loss, hemo- and cytocompatibility, antibacterial and toxicity properties.

TL;DR: In this review biopolymeric nanocomposites provide a closer structural support approximation to native bone architecture for the cells and regulate cell proliferation, differentiation, and migration, which results in bone regeneration.

TL;DR: This review gives an insight to advances in ligand targeted liposomes, stimuli-triggeredliposomes and liposome mediated autophagy modulation, and theranostic liposomal products for the diagnosis and treatment of cancer.

TL;DR: The practical potential of non-conjugated polymeric luminogens as intrinsically luminescent carriers for drug delivery is highlighted, and the opportunities and challenges of using them in theranostics are revisited.

TL;DR: In this article, different types of microneedles such as solid, hollow, dissolving and coated are discussed and various degradable and non-degradable materials used for fabrication are discussed.

TL;DR: In this article, the authors used Aloe socotrina (As) leaf extract and characterized by UV, FTIR, XRD, SEM, and TEM images of the zinc oxide nanoparticles (ZnO NPs) to combat bacterial infection.

TL;DR: The nanomaterials showed promising results and able to support cells adhesion, proliferation and promote neuronal cell differentiation and enhance regeneration of neuron and progress towards neural tissue engineering applications is discussed.

TL;DR: Insight is provided towards novel biopolymers, such as tree gum, wheat protein, soy protein, zein along with their application in drug delivery along with various manufacturing variables that affect the morphology of nanofibers and other processing parameters have been discussed.

TL;DR: A trouble-free, environmentally benign approach for the biogenic synthesis of gold nanoparticles (Au NPs) using the Jasminum auriculatum leaf extract, which acts as a stabilising and reducing agents is reported.

TL;DR: The review aims to provide novel concepts for the design of nanocarriers for the delivery of anti-breast cancer drugs and the application of nano-drug delivery systems in breast cancer therapy.

TL;DR: The dual drug-loaded NFs showed an excellent capacity to inhibit T47D breast cancer cells in vitro than the single drug-encapsulated NFs and may achieve a safe and suitable application for breast cancer relapse rate after surgery.

TL;DR: This review attempts to discuss the recent work on gellan gum hydrogels for the delivery of drug and cell delivery to rejuvenate the tissue.

TL;DR: In this article, a stable antibacterial nanofibrous mat with controlled curcumin release capability through a facile way was fabricated through electrospinning process, where the nanofiber mat was crosslinked through heat treatment at different temperatures and UV exposure for different times with the aim of stabilizing and controlling the release of cur cumin from the mat.

TL;DR: This review discusses about various biomedical applications of phytonanoparticles which are synthesized using plant parts such as shoots, leaves, fruits and roots of different plant species.

TL;DR: The novel PAAm-g-PLN electrically-responsive copolymer is an efficient biomaterial for transdermal delivery of drugs actuated by an electric stimulus and the skin histopathology evaluation suggested a reversible alteration in skin structure when electric stimulation was applied.

TL;DR: The effects of SLN and NLC encapsulating on stability, cellular toxicity, tumor inhibitory effects, oral bioavailability, and biodistribution of synthetic and herbal anticancer medicines are discussed.

TL;DR: The fabricated SA/PVA hydrogel containing drug-loaded CS nanoparticles depicted a great potential as the delivery system for the controlled release of the Rosuvastatin drug.

TL;DR: The niosomal formulation of Span 60, Tween 60, and cholesterol were used to formulate doxycycline-loaded niosomes as a promising drug carrier system as either antibacterial or anticancer formulation, and showed great storage stability for up to 2 weeks and enhanced chemotherapy effect against prostate cancer cells.

TL;DR: The in vivo results showed that wounded rats treated with curcumin loaded LNPs exhibited enhanced dermal wound closure compared with the untreated control, and the results highlight the advantages of using lignin as a nanocarrier to accelerate wound healing.

TL;DR: In this article, the curcumin nanoemulsion was optimized by low-energy emulsification method and converted into nano-emulgel using crosslinked polyacrylic acid (carbopol 934) as a gelling agent.

TL;DR: In this paper, the gold nanoparticles were optimized using concentration of Gum acacia (GA) from (0.25% − 3% w/v) containing 10 mM of Gold (III) chloride trihydrate (HAuCl4·3H2O) with optimum temperature of 80 − 1 ǫ c and reaction time of 30 min.

TL;DR: An insight into the target strategies that can be employed to surpass each barrier of anterior and posterior segment of the eye separately, exploiting its unique nature can aid in the improvement of transport of therapeutic agents across the barriers, achieve optimum drug levels in the targeted tissues and provide sustained/prolong release of drugs with minimal/no side effects.

TL;DR: The present review focusses on various types of CNTs, their modifications, applications, and challenges in cancer therapy.

TL;DR: Ex vivo gut permeation study revealed a good enhancement in penetration of bilosomes compared to ACV solution and marketed formulation which was further confirmed by confocal laser scanning microscopy which showed high penetration of Bilosomes owing to vesicle stability against intestinal bile salts.

TL;DR: Inhalable liposomes for pulmonary delivery present unique advantages as they are formulated from phospholipids similar to endogenous pulmonary surfactant, and their physicochemical properties, aerosolization performance and in-vivo aerodynamic behavior are summarized.

TL;DR: A review of nanotechnology based-therapeutic approaches increasingly acceptable to improve therapeutic efficacy and reduce unwanted effects associated with anticancer payload in breast cancer highlighted the potential of folate-conjugated nanotherapeutics for treatment of breast cancer and challenges pertaining to anticancer therapy.

TL;DR: Carosilane dendrimers display good biocompatibility and can be used for anti-HIV, anti-viral, and anti-inflammatory applications, as well as for delivery of nucleic acids forAnti-cancer therapy.