Showing papers in "Journal of Endocrinology in 1958"

Capacitation of rabbit spermatozoa

Abstract: IT was first reported by Chang1 for the rabbit and by Austin2 for the rat that, even when fertilizable tubal ova were surrounded by active spermatozoa, the latter did not penetrate the zona pellucida unless they had been in the female tract for some hours. Chang3 showed that this delay was associated with a physiological change in the spermatozoa themselves, since he found that if the spermatozoa had been previously kept in the uterus of another female for about 6 hr., fertilization proceeded immediately when the ‘Capacitated’ spermatozoa and ova were brought together. In the rat, ‘capacitation’ takes 2–4 hr.4–6. The following experiments show that the site of ‘capacitation’ is not specific, and that spermatozoa can acquire fertilizing capacity in the spayed female, in the intact male, and in organs quite unrelated to the genital system.

The acute effects of cortisone and cortisol upon renal function in man.

Abstract: were observed regularly both in the course of and without a phosphate infusion. Glomerular filtration rate and renal plasma flow were sometimes markedly elevated, sometimes unaltered. When phosphate was infused in amounts sufficient to saturate tubular reabsorptive capacity, phosphate tubular maximum was often depressed by the hormones, but sometimes unaltered. At normal plasma concentrations the usual relationship between phosphate excretion and plasma concentration or filtered load was undisturbed.

The production of exophthalmos by androgens in two species of teleost fish.

Abstract: Exophthalmos was produced by the androgens methyl testosterone and testosterone phenylacetate, but not by oestradiol dipropionate, in two species of teleost fish, Sparisoma squalidum and Scarus croicensis. Marked exophthalmos was produced by l-thyroxine and 3,5,3\\m='\\-triiodothyronine in the above two species and also in Bathystoma aurolineatum. The thyroidal origin of exophthalmia in fish is discussed.