Journal•ISSN: 0022-1139
Journal of Fluorine Chemistry
Elsevier BV
About: Journal of Fluorine Chemistry is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Trifluoromethyl & Catalysis. It has an ISSN identifier of 0022-1139. Over the lifetime, 9248 publications have been published receiving 139045 citations.
Topics: Trifluoromethyl, Catalysis, Fluoride, Nucleophile, Yield (chemistry)
Papers published on a yearly basis
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TL;DR: The influence of fluorination on acidity, hydrogen-bonding, and lipophilicity that affect compound absorption and distribution is discussed in this paper, and the current perspectives on fluorine steric interactions and the controversial role of hydrogen bonding involving the CF bond are discussed.
1,245 citations
TL;DR: In this paper, a review of fluorinated compounds which have found a role as anti-cancer agents is presented, highlighting the important drugs but also highlighting the latest developments on emerging compounds.
933 citations
TL;DR: Fluorinated drugs for treatment of diseases of the central nervous system, various cardiovascular diseases and obesity, antibacterial agents, and antifungal therapy are reviewed.
779 citations
TL;DR: In this article, the preparation, physical and chemical properties, and application of ionic liquids at ambient conditions are reviewed focusing on the salts of alkylimidazolium cations and fluoroanions.
775 citations
TL;DR: The top 10 fluorine containing pharmaceuticals (by US Sales in 2008) are highlighted in this article, where the structures and modes of action of these important drugs compounds are reviewed and representative synthetic routes are highlighted.
663 citations