Showing papers in "Journal of Geriatric Oncology in 2016"

TL;DR: The relevance of comorbidities in cancer is discussed, the commonly used tools to measure Comorbidity are examined, and the future direction of comorebidity research is discussed.

TL;DR: Assessment of frailty in colorectal oncology seems important to determine operative risks and benefits and to guide perioperative management because frailty is associated with a greater risk of postoperative adverse outcomes.

TL;DR: Evidence regarding the prevalence and impact of polypharmacy in geriatric oncology patients is summarized and recommendations for assessment and management are provided.

TL;DR: Identified knowledge gaps in GA with management studies for older patients with cancer are summarized, proposed areas for future research are proposed and areas for research priorities are proposed.

TL;DR: Current gaps in research highlighting the lack of clinical studies of CRCi in older adults, the complex mechanisms of CRCI, and the challenges in measuring cognitive impairment in older patients with cancer are discussed.

TL;DR: This review will discuss about the different ICB efficacy data available for older patients, highlight the specific spectrum of immunotherapy toxicities and talk about their management in the context of older adults.

TL;DR: Despite growing focus on providing appropriate end-of-life care, there has not been an improvement in aggressive end- of-life cancer care in the Medicare program, as measured by chemotherapy received within 14 days of death, or hospice enrollment ≤3 days before death.

TL;DR: The assessment of sarcopenia may be useful to predict the postoperative pulmonary complications following esophagectomy, but it does not predict cardiac, infectious, and surgical complications or perioperative function.

TL;DR: Use of formal geriatric assessment tools is a promising direction for stratifying older patients on trials, and Elderly-specific trials, adjustments to the eligibility criteria, modified treatment regimens, and interventions to decrease morbidities in the vulnerable older population should be encouraged.

TL;DR: The Cancer and Aging Research Group convened experts in exercise, aging and cancer to evaluate current scientific evidence and knowledge gaps in geriatric exercise oncology and provides future research directions.

TL;DR: A G8-modified test that is more specific than the G8 to detect frail elderly, while still sensitive and feasible in less than 10 min is developed and validated.

TL;DR: The G8 tool identified twice the number of patients as vulnerable compared to the MDT, and there was a trend towards longer postoperative stay and lower radiotherapy completion rates in patients deemed vulnerable by G8 scores.

TL;DR: Health-related quality of life may be improved in older patients after surgery for colorectal cancer, even in patients who are classified as frail preoperatively.

TL;DR: Diabetes is adversely associated with 30-day survival in older AML patients receiving intensive therapy, and the presence of diabetes increased the odds of 30- day mortality by 4.9 (CI 1.6-15.2) times.

TL;DR: Key strategies to accelerate the uptake and impact of educational initiatives to address this gap include the use of effective educational strategies, broad dissemination of educational material that is freely available, and the integration of geriatric oncology topics into teaching, curriculum, assessments and exams.

TL;DR: The International Society of Geriatric Oncology (SIOG) Nursing and Allied Health (NAH) Interest Group described key issues that nurses and allied health care professionals face when caring for older persons with cancer.

TL;DR: The use of START and STOPP criteria by a clinical pharmacist allows identifying PIMs and changing prescriptions for older patients with cancer in agreement with the oncologist and geriatrician of the team.

TL;DR: What is presently known of the interactions of pre-existing cognitive impairment and delirium with cancer is discussed, identified deficits in the knowledge base are discussed, and ways in which innovative research may address these gaps are proposed.

TL;DR: A home-based aerobic and resistance exercise program, EXCAP, shows promise for improving PP in older men with PC on ADT.

TL;DR: An overview of relevant cancer literature within three common clinical scenarios encountered by oncologists include (1) weight loss during anti-cancer therapy, (2) malnutrition during advanced disease, and (3) obesity during survivorship is provided.

TL;DR: By strategically utilizing pragmatic clinical trials to test therapies and interventions that have previously shown efficacy in younger, fitter patients, these trials represent a potential mechanism to improve the evidence base in geriatric oncology and enhance care for older adults with cancer.

TL;DR: Pat-reported functional limitations are prevalent among cancer survivors, and associate with slower gait speeds and shorter survival, which may provide increased insight on long-term prognosis and inform clinical decision-making by identifying subgroups of cancer survivors who may benefit from rehabilitative intervention.

TL;DR: The Cancer and Aging Research Group (CARG), in partnership with the NIA/NCI, held a U13 conference in May 2015 in part to discuss survivorship care for older adults with cancer, and four themes emerged.

TL;DR: A high rate of postoperative complications in this elderly population of patients aged >75 years was highlighted and three significant postoperative risk factors were identified.

TL;DR: Falling is associated with lower HRQOL scores and are associated with a significant prospective decline inHRQOL in older cancer survivors, according to a cross-sectional analysis and a longitudinal analysis.

TL;DR: The majority of older cancer survivors exhibited physical resilience; this was associated with high baseline health, physical function, self-efficacy, and social support and Assessing and targeting psychosocial factors may be important for interventions seeking to promote physical resilience.

TL;DR: IADL function declined slightly whereas physical function remained stable and QOL improved during chemotherapy, and Vulnerable and non-vulnerable older men with mCRPC appear to tolerate 1st-line chemotherapy fairly well.

TL;DR: It is argued that performance status is a crude measure of vulnerability within this cohort of elderly GBM patients and there is a need for specific geriatric assessment models tailored to the elderly neuro-oncology population in order to facilitate treatment decisions.

TL;DR: The CIRS-G scores and LI-scores had poor agreement, indicating that assessment method affects the registration of comorbidity.

TL;DR: Most patients did not actively seek out a CCT, which may reflect a lack of awareness and a need for better education, and older and younger patients in this study gave similar importance to reasons for and against participation in CCTs.