Showing papers in "Journal of Heterocyclic Chemistry in 1972"

TL;DR: In this paper, the synthesis and stereochemistry of various endo2- and exo-2-substituted-7-oxabicyclo[2.2.1]-hept-5-enes and -heptanes are described.

TL;DR: In this article, several compounds were synthesized by cyclization of the requisite fused 2-aminothio-phenene-3-carbonitriles utilizing chloroformamidine hydrochloride in diglyme and three compounds exhibited strong inhibitory effects against Plasmodium berghei in mice and P. falciparum (Uganda I) in vitro.

TL;DR: In this article, the synthesis of 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid derivatives is described, most of which have either an alkoxy or a basic substituent in position 4.

TL;DR: In this paper, the intermediates were not isolated, but cyclized with acid to give isoxazoles or pyrazoles, and they were treated with a variety of nitriles.

TL;DR: The dipole moment in the five-membered heterocyclic rings, furan, thiophene, and pyrrole has the positive pole on the heteroatom as discussed by the authors.

TL;DR: A series of α,α -dimethoxydihydrofurans have been prepared and subjected to various acidic and neutral hydrolysis conditions in attempts to prepare conjugated enediones in a stereospecific manner.

TL;DR: In this paper, the effect of substituents on the chemical shifts of adjacent ring protons is described for a number of new triazole derivatives, which can be used to assign structures to new sym-triazole reaction products.

TL;DR: The structure of 5-diazouracil and several closely related derivatives have been revised on the basis of pmr spectroscopy as mentioned in this paper, and the effect which certain resonance hybrids of the diazo moiety may exert in reactions of the above hetero-cycles and the assignment of S configuration at C-6 for the nucleoside derivatives is also discussed.

TL;DR: In this paper, the reaction of sulfene with 3-dialkylaminomethylene and 4-chromanone gave 1,4-cycloadducts which are derivatives of a new heterocyclic system, i.e., 5H-1,2-oxathiino[5,6-c][1]benzopyran.

TL;DR: Alkylation studies with isopropyl bromide of three 6-(trifluoromethyl)uracils (1, 4, 5) are described in this paper.

TL;DR: In this paper, the 2,5-Dihydro-5-oxo-1,2,4-triazine and some of its alkylated derivatives have been prepared.

TL;DR: In this paper, the structure of 2-β-D-ribofuranosyl-1,2,3-triazole-4-carboxamide from both the corresponding methyl ester and cyano nucleosides is described.

TL;DR: The 3-isochromanone (3) and 3-isoquinolone (4 and 5) derivatives have been investigated and structures assigned to these compounds from spectroscopic studies.

TL;DR: In the presence of base base, thiols react with dichloromaleimides to give 2,3-bis[alkyl(aryl)-mercapto]maleimides as discussed by the authors.

TL;DR: In this paper, the scope of this reaction sequence was determined and several new 3-substituted N-aminopyridinium salts were prepared, including three new 3 substituting N-polymorphic N-Polymorphic Polymorphic Alignant (NPA) chlorides.

TL;DR: In this article, a new synthesis of aromatic methoxy and methylenedioxy substituted 2,3,4,5-tetrahydro-1H-3-benzazepines is described.

TL;DR: The sulfone thieno[2,3-b]pyridine 1,1-oxide (Ib) undergoes Diels-Alder condensation with furan (both exo and endo products formed), anthracene, and naphthacene as mentioned in this paper.

TL;DR: In this article, the preparation of 1-methyl and 1-ethyl-2-nitroimidazole-5-carboxaldehydes (Ia,b) is described.

TL;DR: In this article, the aryl-silicon bond of 2-trimethylsilyl-1-methylimidazole (Ia) was shown to react exothermically at room temperature with four of the five carbonyl reagents, i.e., acid halides, chloroformates, anhydrides and isocyanates.

TL;DR: The N,N-disubstituted dichloroacetamide was the byproduct of the cycloaddition reaction, the formation of which varies according to the substituents on the nitrogen atom as mentioned in this paper, leading to 3-chloro-4-diphenylamino-5,6-tetramethylene-α-pyrone.

TL;DR: An improved 3-step synthesis of 3,4-dihydro-1-methyl-1H-2,1-benzothiazin-4-one 2,2-dioxide has been developed.

TL;DR: The synthesis of β-substituted ethyl sulfates and their reactions with nucleophilic reagents has been studied in this article, where Amines, phenolates, carboxylates, amine oxides, carbanions, and thiophenolates reacted with ethylene sulfate in high yield, with short reaction times, and at low temperatures.