Showing papers in "Journal of Heterocyclic Chemistry in 1981"

TL;DR: In this article, condensation of o-phenylenediamines with carboxylic acids and reaction of bifunctional alkyl halides with bifunctionsal nucleophiles are described.

TL;DR: A series of symmetrically disubstituted compounds, with substituents linked to the ring through a carbon atom, has been prepared from 2,9-dimethyl-1,10-phenanthroline as discussed by the authors.

TL;DR: In this article, the ring transformation occuring in aqueous media of the dihydro intermediates and their salts, respectively appearing during the synthesis of 2-substitutedamino-as-triazino[6,5-c]quinolines, are reported.

TL;DR: In this paper, triethyl orthoformate and formic acid were cyclized with triethyl triazolo[4,3-c]thieno[3,2-e]pyrimidines to give 1.2,4-triazolo [2,3]-triazola[2.3]-pyridines depending on the reaction conditions employed.

TL;DR: In this article, the pyridine ring forming reactions are discussed and the factors determining the formation and regiospecificity of the ring-forming reactions are also discussed, as well as the properties of pyridines.

TL;DR: In this paper, a variety of chelating 1,3-bis(2′-pyridylimino)isoindoline ligands were prepared and characterized including ligands substituted on both the pyridyl and isoindoline ring systems.

TL;DR: In this paper, all isomers of the parent anthra[b]thiophenes and benzo[b]-naphtho[d]thio-phene were synthesized using a new procedure.

TL;DR: The carbocyclic analogs of thymidine, 1- β-ribofuranosylthymine, and 1-β-3′-deoxyribofURanosyl-thymine were synthesized by incorporating modifications into the Shaw method of synthesizing 2,4-(1H,3H)pyrimidinediones via acryloylureas.

TL;DR: In this article, the synthesis of meso-substituted porphyrins was reported, including 5-(R)-10,15,20-tri-p-tolylporphyrins.

TL;DR: In this article, thirty-six methyl carbazoles were prepared, and their synthetic methods were described, including their synthesis methods and their use in the synthesis of synthetic methylcarbazoles.

TL;DR: In this paper, a 3.3 to 1 dominance of the 2S (cis) isomer was shown to epimerize at the C-2 position in neutral, protic solvents, which was manifested by mutarotation concomitant to changes in the ratios of the methine proton resonances in the nmr spectrum.

TL;DR: In this article, a series of 3-oxoalkanoic acid esters with aniline was synthesized for the first time, yielding 2-alkyl-4-methoxyquinolines.

TL;DR: The diquaternary salts 4,4′-(1,3,4-thiadiazole-2,5-diyl)bis(1-methylpyridinium) diiodide and 4, 4′-( 1, 3, 4-oxadiazoles- 2, 5, 5 diyl) bis(1, 5)-bis(2, 5) diide are reduced in aqueous solution in the pH range 5.4-8.0 to radical cations at a potential (Eo) of -0

TL;DR: A series of 6,7-phenanthreno- and 6, 7-acenaphthenopteridines bearing different substituents at positions 2 and 4 are prepared in this article.

TL;DR: The structures of four macrocyclic polyether sulfides have been determined by single crystal x-ray diffraction methods as discussed by the authors, and the compounds studied were 1,4,7-trithia-12-crown-4, 1, 4,dithia 15-c Crown-5, 1.4,ditia 18crown 6, and 1,10-dithias 18c Crown 6.

TL;DR: In this article, the synthesis of all the isomers of pyreno[b]thiophene namely, pyrenono[1,2-b] thiophene, pyrono[2,1-b], pyrenorothiophene and pyrenore[4,5-b].

TL;DR: In this paper, Fischer and Kollmar have been extended to the MNDO SCF-MO method and used in an effort to ascertain the main factors which determine the greater basicity of imidazole and oxazole relative to pyrazole and isoxazole, respectively.

TL;DR: In this article, an improved, general synthesis of 4-aryl-5-pyrimidine carboxylates was reported, which was obtained by using s-triazine with ethyl benzoyl acetate.

TL;DR: In this paper, the synthesis of a number of N-substituted 2-amino-5,8-dimethoxychromones (1) by replacement of the sulphoxide group in 2-ethylsulphinyl-5 8-dimethyloxychromone (5a) with the appropriate amine is described.

TL;DR: In this paper, N-Benzoylthioamides (1) react with hydrazines and hydroxylamine to form 1H-1,2,4-triazoles and 1,2.4-oxadiazoles, respectively.

TL;DR: A series of 3-substituted (chloro, bromo, fluoro or methyl) 7-(3,3-dimethyl-1-triazeno)-10-methylphenothiazines were synthesized as potential antitumor agents.

TL;DR: In this article, the structure of β-deoxy-D-ribonucleoside analogs of biologically active 2-β-Dribofuranosylthiazole-4-carboxamide was determined by X-ray crystallography and 1H nmr.

TL;DR: The reaction of 3,4-dibenzoyl-1-methyl-2,5-diphenylpyrrole (1) and -1-phenylpyrazole (2) with methylamines (3a-c) afforded pyrrolo[3,4c]pyridine (4), and isomeric 2H-pyrazolo[3-4-c]-pyridines (5a-C) and [4,3-c] pyridine (6a- c) respectively

TL;DR: In this paper, methods for the synthesis of substituted diaza-polyoxamacrobicyclic compounds (benzocryptands) are described. And new synthetic routes to cryptand precursors are developed and improvements in eryptand synthesis discussed and employed to prepare some bifunctional cryptands.

TL;DR: A new method for the preparation of 6-(alkyl)amino-3-aryl(alkyl)-1,2,4,5-tetrazines is described, which gives the title compounds in reasonable to excellent yields.

TL;DR: In this article, the cyclization of 2-acetonylthionaphthalene, prepared from 2-mercaptonaphthene (1) and chloro-acetone in the presence of sodium hydroxide, with polyphosphoric acid gave 1-methylnaphtho[2,1-b]thiophene (4) in 64% overall yield from 1.

TL;DR: In this paper, pyridine-Nimine was added to a variety of carboxylic ester dipolarophiles to convert 3-azapyrrocoline esters into acids, amides and hydrazides.

TL;DR: In this article, the phase transfer catalysed alkylation of ambident pyrimidine dianions derived from uracil, thymine, 5-nitrouracil and 5-fluorouracilic, 6-chlorouracili, giving selectively the corresponding N1,N3-dialkyl derivatives in high yield.

TL;DR: In this article, the mutagenic and carcinogenic activity of chryseno and phenanthrothiophene were determined, and the results showed that their mutagenicity can be determined.