Showing papers in "Journal of Heterocyclic Chemistry in 1994"

TL;DR: In this article, a general method was developed for the synthesis of unsymmetrically 3,5-disubstituted 4H-1,2,4-triazoles with allyl or benzyl groups in the 4-ring position.

TL;DR: In this article, alternative methods for the synthesis of 1,3,3-trinitroazetidine (TNAZ) from epichlorohydrin, and benzhydrylamine have been developed.

TL;DR: In this paper, two different methods for the preparation of azacannabinoidal 5H[1]benzopyrano[4,3-b]pyridin-5-ones 24-27, 38, and 39 containing typical structural requirements for ZNS activity were described.

TL;DR: In this paper, the 2-Aryl derivatives were synthesized and their uv and ir spectra were studied and correlation between σ-Hammett constants of aryl substituents and the differences in absorption maxima (Δv = v1-v2 in kK) of the electronic spectra of the deprotonated species were also evaluated.

TL;DR: In this paper, the synthesis of 4-mono and 2,4-disubstituted pyrrolo- [2,1-f][1,2,4]triazines is described.

TL;DR: For the first time fluoropyrimidines were successfully lithiated as mentioned in this paper, and the resulting lithio derivatives were reacted with various electrophiles for the synthesis of new pyrimidine derivatives.

TL;DR: In this paper, the reaction of benzylisonitrile with the hydrochloride salt of diaminomaleonitrile and from reaction of ethyl (Z)-N-(2-amino-1,2-dicyanovinyl)formimidate with benzylamine has been described.

TL;DR: In this article, 2-chloroformylhydrazones of aromatic aldehydes or ketones with various hydrazines were converted to monocarbonohydrazone derivatives and/or tetrahydro-1,2,4,5-tetrazin-3(2H)-one derivatives.

TL;DR: In this article, tryptamines 1a-c were reacted with aldehydes 2a & b and α-keto acids 2c & d to form 1,2,3,4-tetrahydro-β-carbolines (THBCs) 4d-1, and other products, in a buffered solution at 37° and pH 7.4.

TL;DR: A comparison of phenyltrimethyltin vs. phenylboronic acid in the palladium-catalyzed arylation of brominated 5-methyl-1(phenylmethyl)imidazoles is described in this paper.

TL;DR: In this paper, a method of synthesis of unsymmetrical 2,5-diarylthiophenes is described using β-chloroacroleins, prepared from acetophenones, and their condensation with sodium sulfide and various benzyl bromides.

TL;DR: In this article, cyclocondensation reactions of the pyrazol-5-amine 1 and the 1-aryl-3-phenyl-2-propen-1-ones 2a-d yield the 6,7-dihydropyrazolo[1,5-a]pyrimidines 7a-c can be isolated in pure state, 7d is subjected to a spontaneous oxidation.

TL;DR: In this article, 6-Arylthio and 6-arylselenoacyclonucleosides were synthesized and tested for the ability to inhibit replication of HIV-1.

TL;DR: In this paper, a metal-free phthalocyanine with a nitro group as an acceptor substituent and three t-butyl groups as donor groups was synthesized for the first time by mixed condensation of two corresponding diiminoisoindolines.

TL;DR: In this paper, the reaction of 1-(2-nitrophenyl)-5-aminopyrazoles under basic conditions has been reinvestigated and the structures of the obtained pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides confirmed by spectroscopic means.

TL;DR: In this article, 4-Azido-2(1H)-quinolones were thermolyzed in the presence of carboxylic acids and polyphosphoric acid to yield oxazolo[4,5-c]quinolone.

TL;DR: In this article, the reaction of 4,5-diamino-1,6-dihydropyrimidin-6-ones with one equivalent of the chalcones leads in an acidic medium to the formation of the 2,4-diaryl-2,3,6,7-tetrahydro-1H-pyrimido[4,5b][1,4]diazepin- 6-ones 3a-m.

TL;DR: The reaction of 2-styrylbenzoic acids with N-phenylselenosuccinimide (N-PSS) affords 3phenyl-iso-coumarin derivatives via selenolactonization as discussed by the authors.

TL;DR: In this article, the synthesis of methyl 4-oxobutanoate with nitroethane in the presence of 4-dimethylaminopyridine, followed by treatment with acetic anhydride, afforded a nitroacetoxyester 10b.

TL;DR: In this paper, a series of quinoxaline derivatives were obtained through chemical modifications of the 2-cyano and 3-amino groups, and they were tested as cytotoxic agents both in oxic and in hypoxic cells.

TL;DR: In this paper, the authors provide rationalization for the observed regioselectivities and support a mechanism in which the electrophilic trifluoromethyl radicals interact with the aromatic ring at the sites with the greatest electron density of the HOMO orbitals.

TL;DR: In this paper, a new method of synthesis of 1,5-benzodiazepine-2-ones, from 4-hydroxycoumarin and substituted 1,2-phenylenediamines by heating in xylene or acetic acid-ethanol, was reported.

TL;DR: In this article, two chiral dimethyl-substituted phenandhrolino-18crown-6 diester ligands (S,S)-3 and (S-S)-4) were prepared through the reactions of 1,10-phenanthroline-2,9-dicarboxylyl dichloride with 1,S-dimethyl-saturated triethylene glycol and 1 S -dimethylsaturated glycol, respectively.

TL;DR: Based on the Schmidt reaction and an iodolactone ring expansion reaction, two different synthetic routes to substituted 2,3,4,5-tetrahydro-1H-2benzazepines were developed.

TL;DR: In this article, a one-pot synthesis using 5-aminopyrazole derivatives with EMMN, ECA, or diethyl ethoxymethylenemalonate (DEMM) gave pyrazolo-[1,5-a]pyrimidine compounds.

TL;DR: In this paper, the selective bromination with copper(II) bromide of the pyrrole ring in 2-(2'-hydroxybenzoyl)pyrrole (II) in the heterogeneous phase is described, giving in almost quantitative yield the 4,5-dibromo derivative (VI).