Showing papers in "Journal of Heterocyclic Chemistry in 2000"
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TL;DR: A growing number of products, including many heterocycles, can be prepared by the one-pot MultiComponent Reactions (MCRs) just by mixing three or more educts, and in many cases practically quantitative yields of pure products can be obtained as mentioned in this paper.
252 citations
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TL;DR: The synthesis of block and alternating thiophene/phenylene co-oligomers that is based either on the Suzuki coupling reaction or on the Grignard reaction was reported in this article.
148 citations
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TL;DR: In this article, the synthesis of phenyl-capped oligothiophenes via improved synthetic schemes was reported. These schemes are based on the Grignard coupling reaction and enable them to obtain the target compounds at high yields.
110 citations
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53 citations
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TL;DR: In this article, the 4-trifluoromethyl substituted compound has a significantly greater Stokes shift than the comparable compound lacking this group, but both the new coumarins have low fluorescence quantum yields (ϕf).
52 citations
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TL;DR: In this paper, a series of 1,4,5,6,7,8-hexahydroquinolines (9a-j) has been synthesized and their structural features studied by X-ray analysis and theoretical calculations at semi-empirical and ab initio levels.
37 citations
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TL;DR: In this paper, 1.3-dipolar cycloadditions of 1-propargyl-benzotriazol-1-ylmethyl moiety was further elaborated by sequential lithiation and reaction with aldehydes, alkyl halides and Michael acceptors.
36 citations
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TL;DR: In this paper, a set of new N-heterocyclic compounds which are derivatives of 1,10-phenanthroline were described, which could function as tri-, tetra- or hexadentate ligands with transition metal ions.
34 citations
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TL;DR: In this article, 8 new 2-methyl-4(3H)-quinazolinones with one or two chlorine atoms in the benzene ring and a 5-methyl 1,3-thiazol-2-yl substituent in position 3 of the heterocyclic ring were synthesized.
33 citations
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TL;DR: In this article, a semi-synthetic method of (S)-7-(2-isopropylamino)ethylcamptothecin hydrochloride has been developed, based on the Mannich reaction.
32 citations
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TL;DR: In this article, a new method for preparation of quindoline 2 and its O and S analogs was presented, which represents a new way of preparation of the quinoline.
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TL;DR: 2,7-Diazapyrene was synthesized in three high-yield steps from commercially available 1,4,5,8-naphthalene tetracarboxylic diimide.
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TL;DR: In this article, a series of m-and p-substituted 1-phenyl, 1-benzyl and 1-(2-phenylethyl) pyrroles was prepared and their 1H and 13C nmr spectroscopic characteristics were examined.
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TL;DR: In this paper, the synthesis and reactions of 2-hetero-4H-3,1-benzoxazin-4-ones which include oxygen, sulfur and nitrogen substituents are reviewed.
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TL;DR: An improved synthesis for the preparation of 3-oxo-1,2,5-thiadiazolidine 1,1-dioxides has been developed and results in excellent yields of products.
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TL;DR: In this article, the reactions of 4-bromoacetyl-3-methoxy-3methoxyl-6,6-diphenyl-4-[3-(5-alkyl[1,2,4]triazolo[3,4-b]-2,3-dihydro-6H-[1,3, 4]thiadiazinyl)]-1, 2-dioxane in moderate yields (43-46%) were reported.
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TL;DR: In this article, a study of the regiochemistry of cyclo-condensation reaction of s-alkoxyvinyl trihalomethyl ketones with an unsymmetric dinucleophile N-methyl thiourea is presented.
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TL;DR: The rationalization of the synthesis of substituted analogs of megazol, a biologically active 5-nitroimidazole at position 4 of the imidazoles ring, had led to the study of intermediate steps, which revealed that hard nucleophiles on this compound 2 react only with the halogen at the 2 position.
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TL;DR: Condensation of 1-arylhydrazono-1-benzotriazol-1yl 2-propanones (5a-c) with DMF DMA afforded 1-yl-1,4-dihydropyridazine-4-ones as mentioned in this paper.
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TL;DR: The intramolecular Knoevenagel condensation of N-cyclohexyl 3-aryl-2-(2-nitrophenyl)acetoxy-3-oxopropionamides as discussed by the authors obtained from arylglyoxals 2 and cyclohexynyl isocyanide (3) afforded N-Cyclehexyl (Z)-3-aryl -2-hydroxy-3-(2,3-dihydro-2-oxoindol-3 -ylidene)propionamide 8 probably via
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TL;DR: A review of studies toward the enantioselective total synthesis of ircinal A, manzamine A and related compounds is presented in detail in this paper, where a review of their work is presented.
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TL;DR: In this article, the molecular geometries and the torsional potentials about the inter-ring C-C bond in α-oligothiophenes (α-nTh, n=2-4) have been calculated by means of conventional ab initio and density functional theory (DFT) calculations employing the hybrid B3LYP and BH&HLYP functionals.
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TL;DR: In this paper, the mechanism of thiadiazoles formation from both starting classes of compounds, thiobenzamides and N-substituted thiourea, is collected and discussed.
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TL;DR: In this paper, the ring system pyrrolo[3,4-e][1,2,3] triazolo[1,5-a]pyrimidine 6 was obtained in one step by reaction of 3-azidopyrrole 3 and substituted acetonitriles.
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TL;DR: In this article, the authors introduce the concept of recyclization tandems: mesoionic system may be easily transformed to highly reactive oxazolo[3,2-a]pyridinium cation which, in turn, undergoes variety of ring opening/transformation reactions leading to novel classes and subclasses of heterocyclic compounds.
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TL;DR: In this article, the condensation of α,β-unsaturated ketones with substituted o-aminothiophenols, obtained by reductive cleavage of the corresponding disulfides in the presence of triphenylphosphine, is an effective method for the synthesis of 2,4-diaryl-2,3-dihydro-1,5-benzothiazepines under neutral conditions.