Showing papers in "Journal of Heterocyclic Chemistry in 2006"

TL;DR: In this article, a three component coupling of one pot reaction which servers as the most convenient route to the synthesis of benzopyran derivatives using the TiCl4 catalyst (10 mol %) under solvent free conditions is described.

TL;DR: A series of 2-alkyl/aryl benzothiazoles has been synthesized on the basis of the potent and selective in vitro anti-tumor properties of 2-(3,4-diethoxyphenyl)-5-fluorobenzothiazole.

TL;DR: A series of new benzoylquinoxaline derivatives was synthesized and evaluated for antitumor activity against a panel of 60 human cell lines at the NCI of Bethesda and compound 23 exhibited the best profile and growth inhibition activity at 100 - 10 μM.

TL;DR: In this article, a new macrocyclic ligand, L was synthesized using the high dilution condition with condensation of triethylene glycol diamine and terephtalaldehyde in ethanol.

TL;DR: In this article, the condensation of aldehydes with 1,2-phenylenediamine gave the benzimidazole derivatives under mild conditions in good yields.

TL;DR: In this article, the authors showed that the H-10, H-12 E tautomer can be converted into the analogous semicarbazides upon treatment with mesitylnitrile oxide wherein all structures were present in solution as the H10 tautomers with Z conformation about the C13-N14 bond.

TL;DR: In this article, unsymmetrical covariance processing has been applied to HSQC and HMBC spectral data to afford long-range carbon-carbon correlation information equivalent to that obtained from n, 1-, 1, n- and m,n-ADEQUATE spectra.

TL;DR: In this paper, 4.4-Amino-5-bromo-2,4-dichloro-6-methylpyrimidine derivatives were obtained from the newly prepared 5-Bromo 2,4,4 dichlorosimide by sequential treatment with ethanolic ammonia and secondary amines.

TL;DR: Friedlander condensation of 5-aminopyrazole-4-carbaldehydes with formamide 2a or benzamide 2b gave pyrazolo[3,4-d]pyrimidine derivatives as mentioned in this paper.

TL;DR: In this article, a microwave-assisted method for the synthesis of thiazolidine-2,4-dione motif under solvent phase conditions is developed, and a comparative study between the developed microwave methods and the conventional methods is described.

TL;DR: In this article, a tandem reduction-lactamization of dibenz[b,f][1,4]oxazepin-11(10H)-one, 5,10-dihydro-11H-dibenzo [b,e][1 4]-diazepin 11(1]-one and 5,11-Dihydroid-6H-Dibenz-6-one are described.

TL;DR: In this article, the reaction between 3-amino-2,3-dihydro-7,9-dimethyl-2-thioxo-pyrido[3′,2′:4,5]thieno[3,2-d]-pyrimidin-4(1H)-one 4 or its 2-methylthio derivative 5 with hydrazonoyl halides 6 in dioxane in the presence of triethylamine under reflux has followed heterocyclization reaction to yield pyrido

TL;DR: In this article, a simple and convenient method for the synthesis of 1-dialkylaminocarbothioic acid S-[(2,3-epithio)propyl] ester was developed by the reaction of a 1-LDKLDA with 1-chloro-2, 3-epoxypropane in water-methanol mixture at room temperature.

TL;DR: In this article, the reaction of 6-aminopyrimidin-4-ones with benzaldehydes 2 and β-aminocrotononitrile 3 or benzoylacetonitrile 4 under microwave irradiation in dry media yields the 6-cyano-5,8-dihydropyrido[2,3-d]-pyrimidine derivatives.

TL;DR: In this article, the results obtained when five aromatic or heteroaromatic hydrazines react with six β-diketones bearing trifluoromethyl and aryl substituents were reported.

TL;DR: In this article, the authors proposed a single step reaction of N,N′- substituted/-unsubstituted barbituric acids with various alkyl dihalides under phase transfer catalytic conditions using DMF-K2CO3 (base), TBAHSO4 (catalyst) and Br2 (branch).

TL;DR: In this article, a method for Lewis acid catalyzed Nenitzescu indole synthesized 5-hydroxyindoles bearing different substituents in positions 1 )Alk, Bn, Ar), 2 )Me, Et, Ph), and 3 )COOEt, COMe, CONHPh) as well as tricyclic derivatives are reported.

TL;DR: In this paper, a new synthetic route to the total synthesis of (±)-20- epidasycarpidone (1b) is described, which involves acid catalyzed ring closure and the formation of the intermediate 13 in the key step.

TL;DR: In this article, a facile and rapid synthesis of the title compounds via one-pot reaction of 2-aminobenzonitrile, orthoesters and ammonium acetate under solvent-free and microwave condition is described.

TL;DR: In this paper, the one-pot direct synthesis of 2-aminobenzothiazoles from phenyl isothiocyanate and amines using a new reagent of 1-butyl-3-methylimidazolium tribromide ([Bmim]Br3] in ionic liquid 1butyl 3methyloridazolate tetraflouoroborate (BF4) is described.

TL;DR: In this paper, the synthesis of 2-amino-s-triazino[1,2-a] from 2-guanidinobenzimidazoles was successfully carried out by a ring annelation reaction.

TL;DR: In this article, a concise and efficient synthetic approach to 3-arylaminopyrroline-2-ones from anilines and β,γ-unsaturated α-ketoesters in boiling dichloromethane has been developed.

TL;DR: In this article, four-component cyclocondensation of aromatic aldehydes, malononitrile, dimedone and ammonium acetate proceeds under microwave irradiation in solvent free conditions to give highly functionalized hexahydroquinolines.

TL;DR: In this article, the surface active properties such as surface and interfacial tensions, cloud point, foaming height, wetting time, and emulsification power were determined, and the antimicrobial and biodegradability were also screened.

TL;DR: In this paper, the mon-, di-, and triarylation of the pyrimidine ring is described, and a study of solvent and catalyst requirements is conducted, with a specific order of position 4, second in position 6, followed by position 2.

TL;DR: In this article, 1-Acetyl-, 1-propionyl- and 1-phenyl-3,5-diaryl-2-pyrazolines have been synthesized by the reaction of the appropriate α,β-unsaturated ketones with hydrazine or phenylhydrazine in hot acetic acid or propionic acid.

TL;DR: In this paper, a variety of azridine-2-carboxylates have been described and the stereochemistry of these compounds has been determined by spectroscopic methods.

TL;DR: In this paper, the synthesis of new azonia derivatives of thia[6]helicene (1) and thia [7] helicenes (2) is described.

TL;DR: In this paper, the palladium-mediated nucleometalation / methoxycarbonylation of β,γ-unsaturated oximes was used for 3,5-disubstituted Δ2-isoxazolines.

TL;DR: In this paper, the experimental regioselectivity of 1,3-dipolar cycloadditions was established by spectroscopic techniques as well as single crystal X-ray analysis.