Showing papers in "Journal of Heterocyclic Chemistry in 2009"

TL;DR: This review intends to explore synthetic methodologies for the preparation of 2H-chromenes and their analog chromanes through ortho-quinone methide (o-QM) intermediates associated with inter and intramolecular hetero-Diels-Alder and electrocyclization reactions.

TL;DR: In this article, the authors focus on the use of dimethylformamide dimethyl acetal in the preparation of heterocyclic compounds via formylation of active methylene groups, methyl groups to give enamines, and amino groups to giving amidines.

TL;DR: In this article, halogen-free acyclic task-specific ionic liquids (TSILs) were synthesized as novel and recyclable catalysts for the synthesis of 5-oxo-5,6,7,8-tetrahydro-4H-benzo[b]pyrans by one-pot three-component condensation of aromatic aldehyde, malononitrile (or ethyl cyanoacetate), and dimedone (or 1,3-cyclohexanedione) in water.

TL;DR: In this paper, the microwave-assisted Cadogan reaction is modified by using microwave radiation as the source of heat instead of the conventional heating by reflux in a nitrogen atmosphere for several hours.

TL;DR: In this paper, a simple, efficient, and cost-effective method for the synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione derivatives by a one-pot, three-component condensation reaction of phthalazide, dimedone, or 1,3-cyclohexanedione and aromatic aldehydes under CH3CN/DMF (8:2) media at 80°C for 30-60 min in the presence of trimethylsilyl chloride (

TL;DR: In this paper, 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) efficiently catalyzes three-component one-pot condensations of aldehyde, malononitrile and thiophenol to produce highly functionalized pyridines in excellent yield in aqueous ethanol.

TL;DR: In this article, 2, 3 and 4-Chloroquinolines were selectively lithiated at low temperature by lithium diisopropylamide at the more acidic C-3, C-4 and C-5 positions respectively.

TL;DR: A nucleophilic displacement of chloride in 4substituted 2- chloropyrimidines or 2-chloroquinazolines by treatment with 4-methylpiperazine provides compounds that are antagonists of the serotonin 5-HT2A receptor.

TL;DR: In this paper, a high-yielding synthesis of 2,3-dichloroquinoxalines from 2, 3-dihydroxyquinoxaline derivatives is described.

TL;DR: In contrast with the parent compounds, these triazolyl derivatives had no appreciable activity against human immunodeficiency virus (HIV-1) as mentioned in this paper, while the parent compound had a 1,2,3 triazol-1-yl substituent in the 3′ position.

TL;DR: Phenothiazine (10H-dibenzo-1,4-thiazine, I) was obtained for the first time by Bernthsen in 1883 in the thionation of diphenylamine as mentioned in this paper.

TL;DR: In this article, the reactivity of 3,4-diamino-1,2,5-oxadiazole and 3,6-bis-dimethylpyrazol-1yl)-1.2,4,5,5tetrazine was studied.

TL;DR: The results showed that compounds 79 and 80, having pyridine at the position C-2, of benzimidazoles exhibited the greatest activity with MIC values of 6.25–3.12 μg/mL, while indole analogues 108-110 have no inhibitory activity.

TL;DR: 2-Amino-2-chromenes 是异种周期的班团队是的可观的兴趣颜�’，潜在的农业化肥并且是许多自然产品的主要成分。