scispace - formally typeset
Search or ask a question

Showing papers in "Journal of Isfahan Medical School in 2009"



Journal Article
TL;DR: Surfaces bacteria have low potential to spread, but staff hands have many contacts with hospital surfaces, especially with high contact surfaces, therefore it could be a potential source of bacteria transmission from surfaces.
Abstract: Background: Over the past 3 decades of research, it has become apparent that one of the most common surface structures on the archaea and bacteria are monomolecular crystalline arrays of proteinaceous subunits, termed surface layer or S-layer. S-layer protects bacteria to the phagocytosis and prohibits the entry of some biomolecules and adhesion molecules to the matrix proteins which increase the stability of infection and antibiotic resistance in virulence agents. Therefore the spread of bacteria which have S-layer in the hospitals should be avoided. Surfaces can serve as reservoirs of potential pathogen and is important in the chain of infection. Surfaces bacteria have low potential to spread, but staff hands have many contacts with hospital surfaces, especially with high contact surfaces. Therefore it could be a potential source of bacteria transmission from surfaces. Methods: This research was performed between 2005 to 2007, in the Alzahra hospital of Isfahan university of medical sciences. 274 samples were randomly selected (194 sample from surface and 80 sample from staff hand). Environmental samples collected, from high and low contact surface with swab in NB and staff hand. Samples were collected through finger print method and identification of bacteria, were performed with microbiological methods: staining, chemical test, use of differential and selective media. Isolated Bacillus cereus strains, performed with Bacillus cereus Selective Agar, for preparation samples, in first culture Bacteria in TSA, for 16h, then separated surface proteins and finally, specimen's electrophoresis proximally molecular weight marker. S-layer in Bacillus cereus has 97KD molecular weight. Findings: According to the results, the prevalence of Bacillus cereus strains was %9.49. The prevalence of Bacillus cereus strains in environmental and staff hands were respectively %6.7 and %16.25, and of 13 isolated Bacillus cereus from, staff hand 11 strain (84/6%) and from 13 isolated Bacillus cereus from environmental samples 1 strain (7/7%) production S-layer. Conclusion:Result show, high prevalence Bacillus cereus in staff hands and hospital surfaces and frequency surface layer in Bacillus cereus isolated of staff hands into hospital surfaces. Key words: Surface layer, Bacillus cereus, Staff Hands, Hospital Surfaces, Nosocomial Infections.

15 citations


Journal Article
TL;DR: O§USU† U…O·O§U„O¹U‡â€Œ O¨O§ U’¬O³U…US Uˆ O±UˆO§O¯U’s U‚O± O±OˆUS 48 O¹O¨US O¨USU…O¨O± UO’± OaO­u…USU”
Abstract: U…U‚O¯U…U‡: O§O®OaU„O§U„ O¯Uˆ U‚O·O¨US O§O² O§O®OaU„O§U„O§Oa O´O§USO¹ O±UˆO§U†U¾O²O´UƒUS U…US‌O¨O§O´O¯. U‡U…O§U†U†O¯ O¨O³USO§O±US O§O² O¨USU…O§O±US‌U‡O§US O¬O³U…US Uˆ O±UˆO§U†USOŒ O®O§U†UˆO§O¯U‡ O¨USU…O§O±O§U† U…O¨OaU„O§ O¨U‡ O§O®OaU„O§U„ O¯Uˆ U‚O·O¨US UO´O§O±â€ŒU‡O§US O²USO§O¯US O±O§ U…OaO­U…U„ O´O¯U‡OŒ UƒUSUUSOa O²U†O¯U¯US O¢U†O§U† O§UOa U…US‌U†U…O§USO¯.O§USU† U…O·O§U„O¹U‡â€Œ O¨O§ U‡O¯U OaO¹USUSU† O§O«O±O¨O®O´US U…O¯O§O®U„O§Oa O¢U…UˆO²O´US O±UˆO§U†â€ŒO´U†O§O®OaUS O¨O± UO´O§O± OaO­U…USU„US O¨O± O®O§U†UˆO§O¯U‡ Uˆ UƒUSUUSOa O²U†O¯U¯US O®O§U†UˆO§O¯U‡â€ŒU‡O§US O§USU† O¨USU…O§O±O§U† O·O±O§O­US O´O¯U‡ O§O³Oa. O±UˆO´ U‡O§: O§USU† U…O·O§U„O¹U‡â€ŒUŒ UƒO§O±O¢O²U…O§USUS O¨O§U„USU†US O¨O± O±UˆUS 48 O®O§U†UˆO§O¯U‡OŒ O´O§U…U„ U¯O±UˆU‡ U…O¯O§O®U„U‡ Uˆ O´O§U‡O¯ O¯O§O±O§US O¨USU…O§O± U…O¨OaU„O§ O¨U‡ O§O®OaU„O§U„ O¯Uˆ U‚O·O¨US U†UˆO¹ UŒU© O§U†O¬O§U… U¯O±UOa. O¨O±O§US USUƒ O¹O¶Uˆ O®O§U†UˆO§O¯U‡ UƒU‡ U†U‚O´ UƒU„USO¯US O¯O± O®O§U†UˆO§O¯U‡ O¯O§O´OaOŒ U¾O±O³O´U†O§U…U‡â€ŒUŒ UO´O§O± OaO­U…USU„US O¨O± O®O§U†UˆO§O¯U‡ Uˆ UƒUSUUSOa O²U†O¯U¯US O¯O± O²U…O§U†â€ŒU‡O§US O¨O¯Uˆ UˆO±UˆO¯OŒ 3 U…O§U‡ Uˆ 6 U…O§U‡ OaUƒU…USU„ U¯O±O¯USO¯. U…OaOoUSO±â€ŒU‡O§US O¯U…Uˆâ€ŒU¯O±O§UUSUƒ U…O´OaU…U„ O¨O± O³U†OŒ O¬U†O³OŒ U†O³O¨Oa O¨O§ O¨USU…O§O±OŒ OaO¹O¯O§O¯ O³O§O¹O§Oa OaU…O§O³ UO±O¯ O¨O§ O¨USU…O§O± Uˆ U…O¯Oa O´O±UˆO¹ O¨USU…O§O±US O¬U…O¹â€ŒO¢UˆO±US O´O¯. UŒO§UOaU‡ U‡O§: O¯O± O§UŒU† U…O·O§U„O¹U‡OŒ 30 O²U† Uˆ 18 U…O±O¯ O§O² O¨O³OaU¯O§U† O§UO±O§O¯ U…O¨OaU„O§ O¨U‡ O§O®OaU„O§U„O§Oa O¯Uˆ U‚O·O¨UŒ U†UˆO¹ USUƒ O¨O±O±O³UŒ O´O¯U†O¯. O¨USO´OaO±USU† OaO¹O¯O§O¯ O¨O³OaU¯O§U† O¨USU…O§O± O±O§ U‡U…O³O±O§U† Uˆ U…O§O¯O±O§U† O¢U†O§U† O´O§U…U„ U…US‌O´O¯. U…USO§U†U¯USU† O³U†US O´O±UƒOa‌UƒU†U†O¯U¯O§U† 72/10 ± 04/42 O¨UˆO¯. U…UŒO§U†U¯UŒU† U†U…O±U‡â€ŒUŒ UO´O§O± OaO­U…UŒU„UŒ O¨O± O®O§U†UˆO§O¯U‡â€ŒUŒ O¯Uˆ U¯O±UˆU‡ O¯O± U‡USU†UƒO¯O§U… O§O² O³U‡ U…U‚O·O¹ O²U…O§U†UŒ O¨O¯Uˆ U…O¯O§O®U„U‡OŒ O³U‡ U…O§U‡ U¾O³ O§O² O´O±UˆO¹ U…O¯O§O®U„U‡ Uˆ O´O´ U…O§U‡ U¾O³ O§O² O´O±UˆO¹ U…O¯O§O®U„U‡ OaUO§UˆOa U…O¹U†US‌O¯O§O±US U†O¯O§O´Oa. O§U…O§ U©UŒUUŒOa O²U†O¯U¯UŒ O¯O± U¯O±UˆU‡ U…UˆO±O¯ U…O¯O§O®U„U‡ O¯O± O´O´ U…O§U‡ U¾O³ O§O² O´O±UˆO¹ U…O¯O§O®U„U‡â€ŒUŒ O¢U…UˆO²O´UŒ O¨U‡â€ŒO·UˆO± U…O¹U†US‌O¯O§O±US O§UO²O§UŒO´ UŒO§UOaU‡ O¨UˆO¯. U†OaUŒO¬U‡ U¯UŒO±UŒ: U…O¯O§O®U„U‡â€ŒUŒ O¢U…UˆO²O´US O¹O§U…U„US OaO£O«UŒO±â€ŒU¯O°O§O± O¯O± U©USUUSOa O²U†O¯U¯US O¨O± O®O§U†UˆO§O¯U‡ O¨UˆO¯ Uˆ U…US‌OaUˆO§U† O§O² O¢U† O¨U‡â€ŒO¹U†UˆO§U† O§O¨O²O§O±US O¬U‡Oa O¨U‡O¨UˆO¯ UˆO¶O¹USOa O±UˆO§U†US O®O§U†UˆO§O¯U‡â€ŒUŒ O¨USU…O§O±O§U† O±UˆO§U†US O¨U‡O±U‡ U¯O±UOa. UˆO§U˜U¯O§U† U©U„UŒO¯UŒ: U©UŒUUŒOa O²U†O¯U¯UŒOŒ U…O¯O§O®U„O§Oa O¢U…UˆO²O´UŒOŒ O±UˆO§U†â€ŒO´U†O§O®OaUŒOŒ UO´O§O± OaO­U…UŒU„UŒ O¨O± O®O§U†UˆO§O¯U‡

11 citations


Journal Article
TL;DR: Early trachostomy is associated with shorter lengths of stay in ICU and hospital, and need to ventilation support and lower nosocomial pneumonia than in late tracheostomy among patients with severe head injury.
Abstract: BAckground: This study was designed to compare the length of ICU and hospital stay, need to ventilation support, and nosocomial pneumonia, in sever head injury patients, between early and late tracheostomy. Methods: A randomized clinical trial was done. In a period of 2 years, tracheostomy (20 early and 20 late) was did in 40 patients with sever head injury(GCS ≤ 8), without lung disease or severe chest injuries, which was hospitalized in Al-Zahra or Ayatollah Kashani hospitals of Isfahan city. Tracheostomy was defined as early if performed in 4th day of reception. The length of ICU and hospital stay, need to ventilation support, and occurrence of pneumonia was registered. P value < 0.05 considered to indicate statistical significance. Findings: The mean duration of ICU stay in early and late tracheostomy groups was respectively 20.58 and 28.15 days (P = 0.015), and for hospital stay was respectively 30.25 and 36.55 days (P = 0.042). The mean duration need to ventilation support was respectively 8.90 and 12.25 days (P = 0.049). The pneumonia was occurred in early and late tracheostomy in 8 and 19 cases, respectively (P < 0.001). The sex, age, and patient’s GCS in time of reception to ICU or release of it was not associated with kind of tracheostomy. Conclusion: Early tracheostomy is associated with shorter lengths of stay in ICU and hospital, and need to ventilation support and lower nosocomial pneumonia than in late tracheostomy among patients with severe head injury. Key words:Early tracheostomy, Late tracheostomy, Sever head injury, Nosocomial pneumonia, ICU.

10 citations


Journal Article
TL;DR: U…U‚O¯U…u‡: U¾UŒUˆU†O¯ U©O¨O¯ O¨U‡â€Œ U’¤O«O± Uˆ U‚ O§OµU„O§O­ U…O±OaO· O¨O’± U….O±U©O² U… o¨OŒ O¨
Abstract: U…U‚O¯U…U‡: U¾UŒUˆU†O¯ U©O¨O¯ O¨U‡â€Œ O¹U†UˆO§U† OaU†U‡O§ O±O§U‡ O¯O±U…O§U† O¨UŒU…O§O±O§U† U…O¨OaU„O§ O¨U‡ U†O§O±O³O§UŒUŒ U¾UŒO´O±UOaU‡â€ŒUŒ U©O¨O¯ O§O³Oa. U…O±U©O² U¾UŒUˆU†O¯ O´UŒO±O§O² OaU†U‡O§ U…O±U©O² U¾UŒUˆU†O¯ U©O¨O¯ O§UŒO±O§U† O§O³Oa Uˆ OaO¹UŒUŒU† O¨U‚O§UŒ O¨UŒU…O§O±O§U† Uˆ OaO¹UŒUŒU† O§U„U¯UˆU‡O§UŒ U…O¤O«O± Uˆ U‚O§O¨U„ O§OµU„O§O­ U…O±OaO¨O· O¨U‡ O¯U‡U†O¯U‡ Uˆ U¯UŒO±U†O¯U‡ Uˆ UO±O¢UŒU†O¯ U¾UŒUˆU†O¯ U©U‡ O¯O± O¨U‚O§UŒ O§UŒU† O¨UŒU…O§O±O§U† U…O¤O«O±U†O¯OŒ U…UŒâ€ŒOaUˆO§U†O¯ O¨U‡ O¨O±U†O§U…U‡â€ŒO±UŒO²UŒ O¨O§U„UŒU†UŒ O¯O± O¬U‡Oa O§UO²O§UŒO´ O¨U‚O§UŒ O¨UŒU…O§O±O§U† U¾O³ O§O² U¾UŒUˆU†O¯ U©O¨O¯ U…U†O¬O± O´UˆO¯. O±UˆO´ U‡O§: O¯O± O§UŒU† U…O·O§U„O¹U‡â€ŒUŒ U‡U…‌U¯O±UˆU‡UŒOŒ OaU…O§U…UŒ O¨UŒU…O§O±O§U†UŒ U©U‡ O¯O± O³O§U„‌U‡O§UŒ 1380 OaO§ 1387 O¯O± U…O±U©O² U¾UŒUˆU†O¯ O¨UŒU…O§O±O³OaO§U† U†U…O§O²UŒ O´UŒO±O§O²OŒ U¾UŒUˆU†O¯ U©O¨O¯ O§O² O¬O³O¯ O¨O±O§UŒ O¢U†U‡O§ O§U†O¬O§U… O´O¯U‡ O¨UˆO¯OŒ U…UˆO±O¯ O¨O±O±O³UŒ U‚O±O§O± U¯O±UOaU†O¯. O¯O± O§UŒU† O¨O±O±O³UŒ O¨U‚O§UŒ UŒU© O³O§U„U‡OŒ O³U‡ O³O§U„U‡ Uˆ U¾U†O¬ Uˆ O´O´ O³O§U„U‡â€ŒUŒ O¨UŒU…O§O±O§U† U…O­O§O³O¨U‡ U¯O±O¯UŒO¯. U‡U…U†U†UŒU† O§O«O± UO§U©OaUˆO±U‡O§UŒ U…O±OaO¨O· O¨O§ U¯UŒO±U†O¯U‡OŒ O¯U‡U†O¯U‡ Uˆ UO±O¢UŒU†O¯ O¹U…U„ Uˆ O§O±OaO¨O§O· O¢U† O¨O§ O¨U‚O§UŒ O¨UŒU…O§O±O§U† O¨O±O±O³UŒ O´O¯. UŒO§UOaU‡ U‡O§: O¯O± O§UŒU† U…O·O§U„O¹U‡OŒ O¨U‚O§UŒ UŒU© ‌O³O§U„U‡â€ŒUŒ O¨UŒU…O§O±O§U† 84 O¯O±OµO¯ Uˆ O¨U‚O§UŒ O³U‡ O³O§U„U‡ Uˆ O´O´ O³O§U„U‡ 82 O¯O±OµO¯ O¨UˆO¯. O¯O± U…O¯U„ O¨U‚O§UŒ OaU© U…OaOoUŒO±U‡OŒ O§O² O¨UŒU† U…OaOoUŒO±U‡O§UŒ O²U…O§U† O¹U…U„ O·UˆU„O§U†UŒOŒ O³U† O¯U‡U†O¯U‡â€ŒUŒ U¾UŒUˆU†O¯OŒ U†U…O±U‡â€ŒUŒ O¨O§U„O§OaO± MELDOŒ U†UŒO§O² O¨U‡ O¹U…U„ U…O¬O¯O¯ Uˆ UˆO²U† U©U…OaO± O§O² 60 U©UŒU„Uˆ U¯O±U… O¨UŒU…O§O±OŒ O§O±OaO¨O§O· O¨UŒO´OaO±UŒ O¨O§ U©O§U‡O´ O¨U‚O§UŒ O¨UŒU…O§O±O§U† O¯O§O´OaU†O¯. O¯O± U…O¯U„ Cox OaU†U‡O§ O³U† O¯U‡U†O¯U‡â€ŒUŒ U¾UŒUˆU†O¯ O²UŒO±40 O³O§U„ Uˆ O¨O§U„O§UŒ20 O³O§U„ O§O«O± U…O­O§UO¸OaUŒ O¯O± U…O¯U„ U†O´O§U† O¯O§O¯. U†OaUŒO¬U‡ U¯UŒO±UŒ: U…U‚O§UŒO³U‡â€ŒUŒ O¨U‚O§UŒ O¨UŒU…O§O±O§U† U¾UŒUˆU†O¯ O´O¯U‡ O¯O± U…O±U©O² U¾UŒUˆU†O¯ O¨UŒU…O§O±O³OaO§U† U†U…O§O²UŒ U‚O§O¨U„ U…U‚O§UŒO³U‡ O¨O§ U…O±O§U©O² O¨O§ O³O§O¨U‚U‡â€ŒUŒ O¯U†UŒO§ O§O³Oa. O¶U…U† O§UŒU† U©U‡ O¨U‚O§UŒ O¨UŒU…O§O±O§U† O¯O± O³O§U„‌U‡O§UŒ O¢O®O± O¨U‡OaO± O¨O±O±O³UŒ O´O¯U‡ O§O³Oa. UˆO§U˜U¯O§U† U©U„UŒO¯UŒ: U¾UŒUˆU†O¯ U©O¨O¯OŒ O¨U‚O§OŒ UO§U©OaUˆO±U‡O§UŒ U…O±OaO¨O· O¨O§ U¯UŒO±U†O¯U‡â€ŒUŒ U¾UŒUˆU†O¯OŒ O§UŒO±O§U†

9 citations




Journal Article
TL;DR: In this article, the authors proposed a method to improve the performance of U.S. UAVs by reducing the number of UAV-based UAV relays, which they called UAV this article.
Abstract: lU…U‚O¯U…U‡: O¨O§ UˆO¬UˆO¯ O§UŒU†â€Œ U©U‡ U†U¯O±O§U†UŒâ€ŒU‡O§UŒ O²UŒO§O¯UŒ O¯O±O¨O§O±U‡â€ŒUŒ U…OµO±U O§O³UŒO¯U‡O§UŒ U†O±O¨ OaO±O§U†O³ O¨U‡â€ŒO¹U„Oa O§O«O±O§Oa O²UŒO§U†â€ŒO¨O§O± O¢U†â€ŒU‡O§ O¨O± O³U„O§U…OaOŒ O¨U‡â€ŒUˆUŒU˜U‡ O¨UŒU…O§O±UŒâ€ŒU‡O§UŒ U‚U„O¨UŒ- O¹O±UˆU‚UŒ UˆO¬UˆO¯ O¯O§O±O¯OŒ O§O·U„O§O¹O§Oa U…O­O¯UˆO¯UŒ O¯O± U…UˆO±O¯ U…O­OaUˆO§UŒ O§O³UŒO¯U‡O§UŒ U†O±O¨ OaO±O§U†O³ OoO°O§U‡O§UŒ O§UŒO±O§U†UŒ O´O§U…U„ OoO°O§U‡O§US O¢U…O§O¯U‡ O¯O± O¯O³Oa U…UŒâ€ŒO¨O§O´O¯. O¯O± O§UŒU† U…O·O§U„O¹U‡ U…UŒO²O§U† O§O³UŒO¯U‡O§UŒ U†O±O¨ U…O¹U…UˆU„ U…UˆO¬UˆO¯ O¯O± U†U†O¯ U†U…UˆU†U‡ O§O² OoO°O§U‡O§UŒ O¢U…O§O¯U‡â€ŒUŒ O§UŒO±O§U†UŒ O¨O§ OaO£U©UŒO¯ UˆUŒU˜U‡ O¨O± O§O³UŒO¯U‡O§UŒ U†O±O¨ OaO±O§U†O³ U…O´O®Oµ U¯O±O¯UŒO¯U‡ O§O³Oa. O±UˆO´ U‡O§: U†U†O¯ U†UˆO¹ O§O² U¾O±U…OµO±Uâ€ŒOaO±USU† OoO°O§U‡O§US O¢U…O§O¯U‡ O´O§U…U„ O§U†UˆO§O¹ O³UˆO³UŒO³OŒ U©O§U„O¨O§O³OŒ U‡U…O¨O±U¯O± Uˆ U¾UŒOaO²O§ U‡O± UŒU© U‡UOa U…O±OaO¨U‡ O§O² O³UˆU¾O±U…O§O±U©Oa‌U‡O§ Uˆ O±O³OaUˆO±O§U†â€ŒU‡O§ OaU‡USU‡ U¯O±O¯USO¯. 10 U¯O±U… O§O² U‡O± U†U…UˆU†U‡ O¬U‡Oa OaO¹UŒUŒU† U†O±O¨UŒ U©U„ Uˆ O¢U†O§U„USO² O§O³USO¯U‡O§US U†O±O¨ U…UˆO¬UˆO¯ O¯O± U†U…UˆU†U‡â€ŒU‡O§ OaUˆO³O· O¯O³OaU¯O§U‡ U¯O§O²UƒO±UˆU…O§OaUˆU¯O±O§UUS (GC)OŒ O¨O§ O³OaUˆU† U…UˆUŒUŒU†U‡â€ŒUŒ 60 U…OaO±UŒ Uˆ O¯OaU©OaUˆO± UŒUˆU†UŒ O´O¹U„U‡â€ŒO§UŒ O§O³OaUO§O¯U‡ U¯O±O¯USO¯. UŒO§UOaU‡ U‡O§: O¨UŒO´OaO±UŒU† U…UŒO²O§U† O§O³UŒO¯U‡O§UŒ U†O±O¨ O§O´O¨O§O¹ O¯O± OoO°O§U‡O§UŒ O¢U…O§O¯U‡â€ŒUŒ O§UŒO±O§U†UŒOŒ O§O³OaO¦O§O±UŒU© O§O³UŒO¯ (C18:0) U…UŒâ€ŒO¨O§O´O¯ U©U‡ U…UŒO²O§U† O¢U† O§O² 14 OaO§ 9/20 O¯O±OµO¯ U…UŒâ€ŒO¨O§O´O¯. U…UŒO²O§U† O§O³UŒO¯U‡O§UŒ U†O±O¨ O§O´O¨O§O¹ O¯O± U©O§U„O¨O§O³â€ŒU‡O§ U†O³O¨Oa O¨U‡ O³O§UŒO± U¯O±UˆU‡â€ŒU‡O§ O¨U‡â€Œ O·UˆO± U…O¹U†UŒâ€ŒO¯O§O±UŒ O¨O§U„O§OaO± U…UŒâ€ŒO¨O§O´O¯. O§O³UŒO¯U‡O§UŒ U†O±O¨ OaO±O§U†O³ U†O²O¯UŒU© O¨U‡ 6/23 OaO§ 6/30 O¯O±OµO¯ O§O² U©U„ O§O³UŒO¯U‡O§UŒ U†O±O¨ OoO°O§U‡O§US O¢U…O§O¯U‡ O±O§ OaO´U©UŒU„ U…UŒâ€ŒO¯U‡U†O¯. O¨UŒO´OaO±UŒU† O§O³UŒO¯ U†O±O¨ OaO±O§U†O³ U…UˆO¬UˆO¯ O¯O± O§UŒU† U…O­OµUˆU„O§Oa O§U„O§O¦UŒO¯UŒU© O§O³UŒO¯ (trans C18:1, 9) U…UŒâ€ŒO¨O§O´O¯. U…O­OaUˆO§UŒ O§O³UŒO¯U‡O§UŒ U†O±O¨ OoUŒO± O§O´O¨O§O¹ OoO°O§U‡O§US O¢U…O§O¯U‡ 3/25 OaO§ 8/46 O¯O±OµO¯ U…UŒâ€ŒO¨O§O´O¯ Uˆ O§UˆU„O¦UŒU© O§O³UŒO¯ (C18:1, 9cis) Uˆ O³U¾O³ U„UŒU†UˆU„O¦UŒU© O§O³UŒO¯ (C18:2) O¨UŒO´OaO±UŒU† O§O³UŒO¯U‡O§UŒ U†O±O¨ OoUŒO±O§O´O¨O§O¹ U…UˆO¬UˆO¯ O¯O± O§UŒU† U…O­OµUˆU„O§Oa O±O§ OaO´U©UŒU„ U…UŒâ€ŒO¯U‡U†O¯. U†OaUŒO¬U‡ U¯UŒO±UŒ: U†OaO§UŒO¬ O§UŒU† U…O·O§U„O¹U‡ U†O´O§U† U…UŒâ€ŒO¯U‡O¯ U©U‡ U…O­OaUˆO§UŒ O§O³UŒO¯U‡O§UŒ U†O±O¨ OaO±O§U†O³ U…UˆO¬UˆO¯ O¯O± OoO°O§U‡O§UŒ O¢U…O§O¯U‡â€ŒUŒ O§UŒO±O§U†UŒ O¨O³UŒO§O± O¨O§U„O§OaO± O§O² U…UŒO²O§U† U…O¬O§O² (O­O¯O§U©O«O± 2%) U…UŒâ€ŒO¨O§O´O¯. O¨O§ OaUˆO¬U‡ O¨U‡ O§O«O±O§Oa O³UˆOi O§O³UŒO¯U‡O§UŒ U†O±O¨ OaO±O§U†O³ O¨O± O³U„O§U…OaUŒOŒ O­O¶UˆO± O¨O±U†O³O¨â€ŒU‡O§UŒ OoO°O§UŒUŒ U©U‡ U…O´O®Oµâ€ŒU©U†U†O¯U‡â€ŒUŒ U‡U…U‡â€ŒUŒ O§U†UˆO§O¹ O§O³UŒO¯U‡O§UŒ U†O±O¨OŒ O¨U‡ UˆUŒU˜U‡ O§O³UŒO¯U‡O§UŒ U†O±O¨ OaO±O§U†O³ O¨O§O´O¯OŒ U¾UŒO´U†U‡O§O¯ U…UŒâ€ŒU¯O±O¯O¯. UˆO§U˜U¯O§U† U©U„UŒO¯UŒ: O§O³UŒO¯U‡O§UŒ U†O±O¨OŒ O§O³UŒO¯U‡O§UŒ U†O±O¨ OaO±O§U†O³OŒ OoO°O§U‡O§UŒ O¢U…O§O¯U‡OŒ U¯O§O² U©O±UˆU…O§OaUˆU¯O±O§UUŒ

6 citations



Journal Article
TL;DR: U…U‚O¯U…u‡: O¨O§ OaUˆO¬U‡ U…OaUO§ Uˆ O¹U˂O§U… U’O¤O«O± O¨ O± O¢U† O¯O± U…U†O§O·U“ U… O·O§u„O¹ U‚
Abstract: U…U‚O¯U…U‡: O¨O§ OaUˆO¬U‡ O¨U‡ U…OaUO§UˆOa O¨UˆO¯U† O³U† O´O±UˆO¹ U‚O§O¹O¯U¯US Uˆ O¹UˆO§U…U„ U…O¤O«O± O¨O± O¢U† O¯O± U…U†O§O·U‚ U…O®OaU„UOŒ O§USU† U…O·O§U„O¹U‡ O¬U‡Oa O¨O±O±O³US U…UŒO§U†U¯UŒU† O³U† O´O±UˆO¹ U‚O§O¹O¯U¯UŒ Uˆ O¹UˆO§U…U„ U…O¤O«O± O¨O± O¢U† O¯O± O´U‡O±U©O±O¯ O§U†O¬O§U… O´O¯. O±UˆO´ U‡O§: O¯O± O§UŒU† U…O·O§U„O¹U‡â€ŒUŒ OaUˆOµUŒUUŒ - U…U‚O·O¹UŒOŒ O§O² U©U„UŒU‡â€ŒUŒ O¯O®OaO±O§U† O¯O§U†O´â€ŒO¢U…UˆO² 18-11 O³O§U„U‡â€ŒUŒ U…U‚O§O·O¹ O±O§U‡U†U…O§UŒUŒ Uˆ O¯O¨UŒO±O³OaO§U† O´U‡O±O³OaO§U† O´U‡O±U©O±O¯ (8163 U†U…UˆU†U‡) O¨U‡ OµUˆO±Oa O®UˆO´U‡â€ŒO§UŒ 778 U†UO± O§U†OaO®O§O¨ O´O¯U†O¯. O³U¾O³ O¨O±O§US U‡O± USUƒ U¾O±O³O´U†O§U…U‡â€ŒO§UŒ O´O§U…U„ U…O´O®OµO§Oa O¯U…UˆU¯O±O§UUŒU©U€OŒOŒ O³U† O´O±UˆO¹ U‚O§O¹O¯U¯UŒOŒ O´OoU„ U¾O¯O± Uˆ U…O§O¯O±OŒ UˆO²U† U…UˆU‚O¹ OaUˆU„O¯ Uˆ OaO¹O¯O§O¯ O§UO±O§O¯ O®O§U†UˆO§O¯U‡ OaU©U…UŒU„ U¯O±O¯UŒO¯. UŒO§UOaU‡ U‡O§: O§O² 778 U†U…UˆU†U‡â€ŒUŒ O¨O±O±O³US O´O¯U‡OŒ 351 U†UO± (12/45 O¯O±OµO¯) O³O§O¨U‚U‡â€ŒUŒ O­O¯O§U‚U„ USUƒ ‌O¨O§O± U‚O§O¹O¯U¯UŒ O¯O§O´OaU†O¯. U…UŒO§U†U¯UŒU† O³U† O§UˆU„UŒU† U‚O§O¹O¯U¯UŒ O¯O± O´U‡O±O³OaO§U† O´U‡O±U©O±O¯ 15/1 ± 7/12 O³O§U„OŒ U©U…OaO±UŒU† O³U† U‚O§O¹O¯U¯UŒ 8 O³O§U„ Uˆ2 U…O§U‡ Uˆ O¨UŒO´OaO±UŒU† O³U† U‚O§O¹O¯U¯UŒ 15O³O§U„ Uˆ 10 U…O§U‡ O¨UˆO¯. O³U† O´O±UˆO¹ U‚O§O¹O¯U¯US O¯UŒO±O±O³ 15 O³O§U„ (5/4 O¯O±OµO¯) Uˆ O´O±UˆO¹ U‚O§O¹O¯U¯US O²UˆO¯O±O³ 10O³O§U„ Uˆ 5 U…O§U‡ (99/1 O¯O±OµO¯) O¨UˆO¯. O¨UŒU† O³U† O§UˆU„UŒU† U‚O§O¹O¯U¯UŒ Uˆ UˆO²U† U…UˆU‚O¹ OaUˆU„O¯ O±O§O¨O·U‡â€ŒO§US UˆO¬UˆO¯ U†O¯O§O´Oa UˆU„UŒ O§UŒU† O³U† O¨O§ O´OoU„ U…O§O¯O±OŒ UˆO¶O¹UŒOa O§U‚OaOµO§O¯UŒ - O§O¬OaU…O§O¹UŒ Uˆ O¨O¹O¯ O®O§U†UˆO§O± O±O§O¨O·U‡â€ŒUŒ U…O¹U†UŒâ€ŒO¯O§O±UŒ O¯O§O´Oa. U†OaUŒO¬U‡ U¯UŒO±UŒ: U…UŒO§U†U¯UŒU† O³U† O´O±UˆO¹ U‚O§O¹O¯U¯UŒ O¯O± O´U‡O±U©O±O¯ U‡U…O§U†U†O¯ O³O§UŒO± U…U†O§O·U‚ U©O´UˆO± O±UˆU†O¯ O±Uˆ O¨U‡ U©O§U‡O´UŒ O¯O§O´OaU‡ O§O³Oa U©U‡ O¨U‡ O¹U„Oa O§O±OaU‚O§UŒ UˆO¶O¹UŒOa O§U‚OaOµO§O¯UŒ – O§O¬OaU…O§O¹US - O¨U‡O¯O§O´OaUŒ Uˆ O¨U‡O¨UˆO¯ UˆO¶O¹UŒOa OaOoO°UŒU‡ U…US‌O¨O§O´O¯. O¯O³OaO§UˆO±O¯U‡O§US O§UŒU† U…O·O§U„O¹U‡ U…UŒâ€ŒOaUˆO§U†O¯ O¨U‡ O¹U†UˆO§U† U…O¨U†O§UŒUŒ O¬U‡Oa O¨O±O±O³UŒ O±UˆU†O¯ OaOoUŒUŒO±O§Oa O§UŒU† O´O§O®Oµ O¯O± U…O·O§U„O¹O§Oa O¢USU†O¯U‡ O¨U‡ U©O§O± O±UˆO¯. UˆO§U˜U¯O§U† U©U„UŒO¯UŒ :O³U† O´O±UˆO¹ U‚O§O¹O¯U¯UŒOŒ O¯O®OaO±O§U† O¯O§U†O´â€ŒO¢U…UˆO²OŒ O´U‡O±U©O±O¯OŒ U…UŒO§U†U¯UŒU†

5 citations



Journal Article
TL;DR: It is revealed that one exposure to MAMP particularly at the high dose can change the proliferation/apoptosis ratio of spermatogonia in rat testis, which would adversely affect the normal sperMatogenesis process and could lead to disturbances in male fertility.
Abstract: Background: Methamphetamine (MAMP) is a central nervous system stimulant that is increasingly abused by teenagers and young adults. The MAMP effects on the male reproductive system are not clear. In this experimental study, we evaluated the effects of single injection of three different doses of MAMP on the proliferation and apoptosis of the sperm germ cells in the mature rat. Methods: A single dose of MAMP in different doses (1, 5 or 15 mg/kg) or normal saline was administered intraperitoneally in four groups of mature male rats. The right and left tissue sections were immunostained with immunohistochemical methods for proliferation and apoptosis, respectively. Indexes were calculated for proliferating and apoptotic cells. Findings: Cell proliferation decreased significantly in the group which treated with the highest dose. The ratio of proliferation to apoptosis decreased significantly in two groups with the highest doses. Conversely, apoptosis occurrence was increased in these groups. In the control group, more than 95% of spermatogonia were proliferating cells; however, 15mg/kg of MAMP caused an 85% reduction in the number of proliferating spermatogonia. On the contrary, the number of apoptotic cells at least doubled in some tubules of these groups. There were significant differences between the lower dose group and the higher doses groups. Therefore, the observed differences were relatively dose-dependent. Conclusion: This study revealed that one exposure to MAMP particularly at the high dose can change the proliferation/apoptosis ratio of spermatogonia in rat testis. Therefore, this would adversely affect the normal spermatogenesis process and could lead to disturbances in male fertility. Key words: Methamphetamine, Cell proliferation, Apoptosis, Sperm germ cells, Rat.

Journal Article
TL;DR: U…u‚O¯U…U‡: O´U†O§O®Oa O¹UˆO§U…O’·O·O± O¢O³U… U†U‚ o´ U…UŒ O¯O± U¾ UŒO´U¯U ŒO±OŒ o§O² O§O¹O‡ O¨O±
Abstract: U…U‚O¯U…U‡: O´U†O§O®Oa O¹UˆO§U…U„ O®O·O± O¢O³U… U†U‚O´ U…U‡U…UŒ O¯O± U¾UŒO´U¯UŒO±UŒ O§O² O§UŒO¬O§O¯ Uˆ U©O§U‡O´ O¹U„O§UŒU… O¢U† O¯O± U©UˆO¯U©O§U† O§UŒUO§ U…UŒâ€ŒU©U†O¯. U‡O¯U O§UŒU† U…O·O§U„O¹U‡ O¨O±O±O³UŒ O§O±OaO¨O§O· O´O§O®Oµ OaUˆO¯U‡â€ŒUŒ O¨O¯U†UŒ Uˆ O¢O³U… O¯O± U©UˆO¯U©O§U† O¨UˆO¯. O±UˆO´ U‡O§: O¯O± O§UŒU† U…O·O§U„O¹U‡â€ŒUŒ U…UˆO±O¯ - O´O§U‡O¯UŒOŒ 138 U©UˆO¯U© U…O¨OaU„O§ O¨U‡ O¢O³U… (U¯O±UˆU‡ U…UˆO±O¯) Uˆ 138 U©UˆO¯U© OoUŒO± U…O¨OaU„O§ O¨U‡ O¢O³U… (U¯O±UˆU‡ O´O§U‡O¯) O¯O± UŒU© O¯UˆO±U‡â€ŒUŒ 8 U…O§U‡U‡ (1384 O§U„UŒ 1385) O¨O±O±O³UŒ O´O¯U†O¯. U†U…UˆU†U‡â€ŒU¯UŒO±UŒ O¬U‡Oa U¯O±UˆU‡ U…UˆO±O¯ O¨U‡ O±UˆO´ O¢O³O§U† Uˆ U…OaUˆO§U„UŒ O§O² O¨UŒU† U©UˆO¯U©O§U† 5 OaO§ 15 O³O§U„U‡â€ŒUŒ U…O¨OaU„O§ O¨U‡ O¢O³U…OŒ U…O±O§O¬O¹U‡ U©U†U†O¯U‡ O¨U‡ O¯O±U…O§U†U¯O§U‡ O±UŒU‡â€ŒUŒ O¨UŒU…O§O±O³OaO§U† O§U„O²U‡O±O§ (O³) (O§OµUU‡O§U†) Uˆ U†U…UˆU†U‡â€ŒU¯UŒO±UŒ O¬U‡Oa U¯O±UˆU‡ O´O§U‡O¯ O¨U‡ O±UˆO´ OaOµO§O¯UUŒ O§O² O¨UŒU† U©UˆO¯U©O§U† 5 OaO§ 15 O³O§U„U‡ OoUŒO± U…O¨OaU„O§ O¨U‡ O¢O³U… U…O±O§O¬O¹U‡ U©U†U†O¯U‡ O¨U‡ U…O±U©O² O¨U‡O¯O§O´OaUŒ - O¯O±U…O§U†UŒ O§O¨U† O³UŒU†O§ (O§OµUU‡O§U†) U©U‡ O´U©O§UŒOaUŒ O§O² O¹U„O§UŒU… OaU†UO³UŒ U†O¯O§O´OaU†O¯OŒ O§U†O¬O§U… O´O¯. UˆO²U† Uˆ U‚O¯ U©UˆO¯U©O§U† O§U†O¯O§O²U‡â€ŒU¯UŒO±UŒ Uˆ O´O§O®Oµ OaUˆO¯U‡â€ŒUŒ O¨O¯U†UŒ (Body Mass Index UŒO§ BMI) O¨O§ O¬O¯O§UˆU„ O§O³OaO§U†O¯O§O±O¯ O¢U† O¨O±O§UŒ O³U† Uˆ O¬U†O³ OaO·O¨UŒU‚ O¯O§O¯U‡ O´O¯. UŒO§UOaU‡ U‡O§: O¨UŒU† O¯Uˆ U¯O±UˆU‡ O¯O± O³U† Uˆ O¬U†O³ OaUO§UˆOa U…O¹U†UŒâ€ŒO¯O§O±UŒ U…O´O§U‡O¯U‡ U†O´O¯ (05/0 P >). U…UŒO§U†U¯UŒU† UˆO²U† O¯O± U©UˆO¯U©O§U† U…O¨OaU„O§ O¨U‡ O¢O³U… (13 ± 6/38 U©UŒU„UˆU¯O±U…) O¨U‡ O·UˆO± U…O¹U†UŒâ€ŒO¯O§O±UŒ U©U…OaO± O§O² U©UˆO¯U©O§U† OoUŒO± U…O¨OaU„O§ (2/15 ± 2/53 U©UŒU„UˆU¯O±U…) O¨UˆO¯ (001/0 P ). U†OaUŒO¬U‡ U¯UŒO±UŒ: O¨O± O®U„O§U O¨UŒO´OaO± U…O·O§U„O¹O§Oa U¯O°O´OaU‡OŒ O¯O± O¬O§U…O¹U‡â€ŒUŒ U…UˆO±O¯ O¨O±O±O³UŒ U…O§ O§O±OaO¨O§O·UŒ O¨UŒU† O´O¯Oa O¢O³U… O¨O§ O´O§O®Oµ OaUˆO¯U‡â€ŒUŒ O¨O¯U†UŒ UŒO§UOa U†O´O¯. O§U†O¬O§U… U…O·O§U„O¹O§Oa O¢UŒU†O¯U‡ U†U¯O± Uˆ U‡U…U†U†UŒU† O¨O±O±O³UŒ O§O«O± O¨O®O´UŒ U…O¯O§O®U„O§Oa U¾UŒO´U¯UŒO±O§U†U‡ O¯O± O§UŒU† O²U…UŒU†U‡ U¾UŒO´U†U‡O§O¯ U…UŒâ€ŒO´UˆO¯. UˆO§U˜U¯O§U† U©U„UŒO¯UŒ: O¢O³U…OŒ O¢U„O±U˜UŒOŒ U†O§U‚UŒOŒ O´O§O®Oµ OaUˆO¯U‡â€ŒUŒ O¨O¯U†UŒOŒ U©UˆO¯U©O§U†


Journal Article
TL;DR: Both obese and nonobse PCOS patients show different presentations and it is necessary to do more studies to compare clinical features of PCOS in obese andNonobese patients for early diagnosis and management.
Abstract: Background: Considering the heterogenicity of polycystic ovary syndrome (PCOS), the diagnosis is difficult. The aim of present study was to compare ovarian morphology, pattern of menstrual cycles and testosterone level in obese and non obese polycystic ovary syndromepatients. Methods: Clinical characteristics, hormonal profile and ovarian morphology were evaluated in 54 women with polycystic ovary syndrome, aged 21-48 years. They were devided in 2 groups regarding Body Mass Index; obese (BMI ≥ 25) and nonobese (BMI < 25). Fidings were statistically analyzed. Findings: Mean BMI was 28.5 ± 3.2 in obese group and 21 ± 2.6 kg/m2 in nonobese group. Menstrual cycles were regular in 11 patients (20.4%) and irregular in 43 patients (79.6%). BMI was 23.6 ± 3.6 in patients with regular cycles and 25 ± 5 in those with irregular cycles (P = 0.36). Mean testosterone level was 7.1 ± 1.7 in obese and 5.6 ± 2.9 ng/ml in nonobese group (P = 0.69). In obese group, ovarian morphology was normal in only 8 patients (29.6%) and abnormal in 19 patients (70.4%) (P = 0.039) and in nonobese group 12 patients (44.4%) had normal morphology and 15 patients (55/6%) had abnormal morphology. (P = 0.039). Conclusion: Our study suggests that there is significant correlation between BMI and ovarian morphology but there is no significant difference between BMI and menstrual cycle or BMI and testosterone level. Thus both obese and nonobse PCOS patients show different presentations and it is necessary to do more studies to compare clinical features of PCOS in obese and nonobese patients for early diagnosis and management. Key words: Polycystic ovary syndrome, Body Mass Index, Ovarian morphology, Testosterone.

Book ChapterDOI
TL;DR: Two physicochemical parameters, oxygen tension and pH, was changed to measure the lactate production after 1, 2 and 3 days culture and GAG(glycosaminoglycan) production after 3, 7 and 14 days culture of chondrocytes on DegraPol®, as a biodegradable polyurethane scaffold (BPUS), and alginate scaffolds and the results showed that physic biochemical parameters could change cell metabolism.
Abstract: There are some different methods in the literatures that used for healing and repairing of cartilage. One of the methods for increasing of regeneration and metabolism in cartilage, is stimulating physicochemical parameters on cellpolymer systems, as cartilage based cells. In this research, two physicochemical parameters, oxygen tension and pH, was changed to measure the lactate production after 1, 2 and 3 days culture and GAG(glycosaminoglycan) production after 3, 7 and 14 days culture of chondrocytes on DegraPol®, as a biodegradable polyurethane scaffold (BPUS), and alginate scaffolds. The results finally were compared on both scaffolds. The results showed that physicochemical parameters like oxygen tension and pH could change cell metabolism. In fact, the physicochemical parameters could affect lactate production and GAG content of chondrocyte cells and it does not depend on the type of scaffold. The best condition of the articular chondrocytes metabolism was for 5% O2 and pH=7.4(p<0.001). The comparison between BPUS and alginate scaffold is showing that the results are better for alginate beads (p<0.001). In fact, hydrophilicity of alginate causes better cell distribution and nutrition than BPUS; because the cells are able to transfer the ions and the products through the medium easily.

Journal Article
TL;DR: U… U‚O¯U U…O·O§U„O¹U‡â€ŒUŒ O­O§O¶O± U…U‚‡O§USO³U’¬US Uˆ O§O±O²USO· O¨O± O¾USO´â€ ŒO¨USU†US O±O®O¯O§
Abstract: U…U‚O¯U…U‡: U‡O¯U U…O·O§U„O¹U‡â€ŒUŒ O­O§O¶O± U…U‚O§USO³U‡â€ŒUŒ U‚O¯O±Oa O´O§O®Oµâ€ŒU‡O§US OaU†â€ŒO³U†O¬US Uˆ O§O±O²USO§O¨US U†U‚O§O· O¨O±O´ O¢U†â€ŒU‡O§ O¯O± U¾USO´â€ŒO¨USU†US O±O®O¯O§O¯ U‚U„O¨US O¹O±UˆU‚US O¯O± O¬U…O¹USOa O§USO±O§U† U…US‌O¨O§O´O¯. O±UˆO´â€ŒU‡O§: O§USU† U…O·O§U„O¹U‡â€ŒUŒ O¢USU†O¯U‡â€ŒU†U¯O± O¬U…O¹USOaUSOŒ O´O§U…U„ 1614 U…O±O¯ Uˆ 2006 O²U† 40 O³O§U„U‡ UŒO§ O¨O§U„O§OaO± O´O±UƒOa‌UƒU†U†O¯U‡ O¯O± U…O·O§U„O¹U‡â€ŒUŒ U‚U†O¯ Uˆ U„USU¾USO¯ OaU‡O±O§U† O¨UˆO¯ UƒU‡ O¯O± U¾O§USU‡ O¨O¯UˆU† O±O®O¯O§O¯ U‚U„O¨US O¹O±UˆU‚US O´U†O§O®OaU‡ O´O¯U†O¯ Uˆ O¨O±O§US U…USO§U†U‡â€ŒUŒ 6/7 O³O§U„ U¾USU¯USO±US O´O¯U†O¯. U†O³O¨Oa‌U‡O§US O®O·O± O´O§O®Oµâ€ŒU‡O§US OaU†â€ŒO³U†O¬US O¨O±O§US U¾USO´â€ŒO¨USU†US O±O®O¯O§O¯ U‚U„O¨US O¹O±UˆU‚USOŒ U¾O³ O§O² OaO¹O¯USU„ O±USO³Uƒ UO§UƒOaUˆO±U‡O§US U‚U„O¨US O¹O±UˆU‚US O¯O± O·US 6/7 O³O§U„ U¾USU¯USO±US U…O­O§O³O¨U‡ O´O¯. UŒO§UOaU‡â€ŒU‡O§: O¯O± O·UˆU„ U…O·O§U„O¹U‡OŒ 333 O±O®O¯O§O¯ U‚U„O¨US O¹O±UˆU‚US U…O´O§U‡O¯U‡ O´O¯. U†O³O¨Oa‌U‡O§US O®O·O± OaO¹O¯USU„ O´O¯U‡ OaU…O§U… O´O§O®Oµâ€ŒU‡O§US OaU†â€ŒO³U†O¬US O¯O± U…O±O¯O§U† Uˆ O´O§O®Oµ U†O³O¨Oa O¯UˆO± UƒU…O± O¨U‡ O¨O§O³U† O¯O± O²U†O§U† O¨O±O§US U¾USO´â€ŒO¨USU†US O±O®O¯O§O¯ U‚U„O¨US- O¹O±UˆU‚US U…O¹U†US‌O¯O§O± O¨UˆO¯ UƒU‡ O¨U‡ ‌OaO±OaUSO¨ 19/1OŒ 24/1OŒ 21/1 Uˆ 24/1 O¨O±O§US U†U…O§USU‡â€ŒUŒ OaUˆO¯U‡â€ŒUŒ O¨O¯U†USOŒ O¯UˆO± UƒU…O±OŒ O¯UˆO± UƒU…O± O¨U‡ O¨O§O³U† Uˆ O¯UˆO± UƒU…O± O¨U‡ U‚O¯ O¯O± U…O±O¯O§U† Uˆ 27/1 O¨O±O§US O¯UˆO± UƒU…O± O¨U‡ O¨O§O³U† O¯O± O²U†O§U† O¨UˆO¯ (05/0 > P). O¢U†O§U„USO² O±O§Uƒ O¨USO´OaO±USU† O³O·O­ O²USO±U…U†O­U†US O±O§ O¨O±O§US O´O§O®Oµâ€ŒU‡O§US U†O³O¨Oa O¯UˆO± UƒU…O± O¨U‡ O¨O§O³U†OŒ O¯UˆO± UƒU…O± O¨U‡ U‚O¯ Uˆ O¯UˆO± UƒU…O± Uˆ O¨U‡ ‌O¯U†O¨O§U„ O¢U†â€ŒU‡O§ U†U…O§USU‡â€ŒUŒ OaUˆO¯U‡â€ŒUŒ O¨O¯U†US O¯O± UƒU„ U…O±O¯O§U† U…O·O§U„O¹U‡ Uˆ O¯O± U‡O± O¯Uˆ O¬U†O³ O²USO± 60 O³O§U„ U†O´O§U† O¯O§O¯. O¯O± O²U†O§U†OŒ U†O³O¨Oa O¯UˆO± UƒU…O± O¨U‡ O¨O§O³U† Uˆ O¯UˆO± UƒU…O± O¨U‡ U‚O¯ O¨USO´OaO±USU† O³O·O­ O²USO± U…U†O­U†US O±O§ O¯O§O´OaU†O¯. U†U‚O§O· O¨O±O´ U…O·U„UˆO¨ O¯O± U¾USO´â€ŒO¨USU†US O¨O±UˆO² O±O®O¯O§O¯ U‚U„O¨US- O¹O±UˆU‚US O¯O± U…O±O¯O§U† Uˆ O²U†O§U† O²USO± 60 O³O§U„ O¨U‡ ‌OaO±OaUSO¨ 95/26 Uˆ 84/29 kg/m2 O¨O±O§US U†U…O§USU‡â€ŒUŒ OaUˆO¯U‡â€ŒUŒ O¨O¯U†USOŒ 4/94 Uˆ 5/90 O³O§U†OaUŒâ€ŒU…OaO± O¨O±O§US O¯UˆO± UƒU…O±OŒ 95/0 Uˆ 89/0 O¨O±O§US O¯UˆO± UƒU…O± O¨U‡ O¨O§O³U† Uˆ 55/0 Uˆ 60/0 O¨O±O§US O¯UˆO± UƒU…O± O¨U‡ U‚O¯ O¨UˆO¯. U†OaUSO¬U‡â€ŒU¯USO±US: O¯O± U…O±O¯O§U†OŒ O´O§O®Oµâ€ŒU‡O§US OaU†â€ŒO³U†O¬US U…O±UƒO²US Uˆ O¹U…UˆU…US OaUO§UˆOaUS O¯O± U¾USO´â€ŒO¨USU†US O±O®O¯O§O¯ U‚U„O¨US- O¹O±UˆU‚US U†O´O§U† U†O¯O§O¯OŒ O­O§U„ O¢U†â€Œ UƒU‡ O¯O± O²U†O§U† U†O³O¨Oa O¯UˆO± UƒU…O± O¨U‡ O¨O§O³U† Uˆ O¯UˆO± UƒU…O± O¨U‡ U‚O¯ U…U†O§O³O¨â€ŒOaO±USU† O´O§O®Oµâ€ŒU‡O§ O¨UˆO¯U†O¯. U†U‚O§O· O¨O±O´ O´O§O®Oµâ€ŒU‡O§US OaU†â€ŒO³U†O¬US O¨O±O§US U¾USO´â€ŒO¨USU†US O±O®O¯O§O¯ U‚U„O¨US- O¹O±UˆU‚US O¯O± O¬U…O¹USOa O§USO±O§U† O¨O§U„O§OaO± O§O² O¯USU¯O± O¬U…O¹USOa‌U‡O§US O¢O³USO§USUS O¨UˆO¯. U‡U…‌U†U†USU† U†U‚O·U‡â€ŒUŒ O¨O±O´ O¯UˆO± UƒU…O± O¯O± O¬U…O¹USOa U…O°UƒUˆO± U…OaO£O«O± O§O² O¬U†O³ USO§UOa U†O´O¯. UˆO§U˜U¯O§U† UƒU„USO¯US: O´O§O®Oµâ€ŒU‡O§US U†O§U‚USOŒ O±O®O¯O§O¯ U‚U„O¨US- O¹O±UˆU‚USOŒ U†O§U‚US U…O±UƒO²US.

Journal Article
TL;DR: Table Normal 0 false false false EN-US X-NONE FA MicrosoftInternetExplorer4 st1\:*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable
Abstract: Normal 0 false false false EN-US X-NONE FA MicrosoftInternetExplorer4 st1\:*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} U†U©UŒO¯U‡ lU…U‚O¯U…U‡: O¯O± O­O§U„ O­O§O¶O± O§U†OaO®O§O¨ O§O³U¾O±U… O¬U‡Oa ICSI O¨O± O§O³O§O³ U…O¹UŒO§O±U‡O§UŒ U…UˆO±UUˆU„UˆU˜US Uˆ OaO­O±U© O§O³Oa. O§U…U‘O§ O§UŒU† U¾O§O±O§U…OaO±U‡O§ UˆO¬UˆO¯ USO§ O¹O¯U… UˆO¬UˆO¯ O§U†UˆO§O¹ U†O§U‡U†O¬O§O±UŒ‌U‡O§US U©O±UˆU…O§OaUŒU† O±O§ U¾UŒO´U¯UˆUŒUŒ U†U…US‌U©U†O¯. O¨U†O§O¨O±O§UŒU† UˆO¬UˆO¯ O±UˆO´‌U‡O§UŒUŒ U©U‡ O¨OaUˆO§U†U†O¯ O¹U„O§UˆU‡ O¨O± O®OµUˆOµUŒO§Oa O¸O§U‡O±UŒOŒ O§O³U¾O±U…‌U‡O§UŒ O¨O§ U©O±UˆU…O§OaUŒU† O·O¨UŒO¹UŒ O±O§ O¬O¯O§ U©U†O¯OŒ O¶O±UˆO±UŒ U…UŒ‌O¨O§O´O¯. O¯O± O§UŒU† OaO­U‚UŒU‚ U©O§O±O¢UŒUŒ O¯Uˆ O±UˆO´ O¬O¯O§O³O§O²UŒ O§O³U¾O±U… HA-binding Uˆ Zeta O¯O± O¬O¯O§O³O§O²UŒ O§O³U¾O±U…‌U‡O§UŒ O¨O§U„Oo O§O² U†O¸O± U…UŒO²O§U† U†O§U‡U†O¬O§O±UŒ‌U‡O§UŒ U…UˆO±UUˆU„UˆU˜UŒOŒ U©U…O¨UˆO¯ U¾O±UˆOaO§U…UŒU† Uˆ UO±O§U¯U…U†OaO§O³UŒUˆU† DNA U…UˆO±O¯ O¨O±O±O³UŒ U‚O±O§O± U¯O±UOa. O±UˆO´ U‡O§: O¯O± O§USU† OaO­U‚USU‚ O§O² U†U…UˆU†U‡ ‌UŒ O³U…U†70 O²UˆO¬ U†O§O¨O§O±UˆO± U…O±O§O¬O¹U‡ UƒU†U†O¯U‡ O¨U‡ U…O±UƒO² O¨O§O±UˆO±US Uˆ U†O§O¨O§O±UˆO±US O§OµUU‡O§U† O§O³OaUO§O¯U‡ O´O¯. O¨O± O±UˆUŒ U†U…UˆU†U‡‌UŒ O³U…U† O¯Uˆ O±UˆO´ O¬O¯O§O³O§O²UŒ HA-binding Uˆ Zeta O§U†O¬O§U… U¯O±UOa Uˆ O¨O± O±UˆUŒ O§O³U¾O±U…‌U‡O§UŒ O­O§OµU„ O§O² O¯Uˆ O±UˆO´ O¬O¯O§O³O§O²UŒOŒ O±U†U¯‌O¢U…UŒO²UŒ U¾O§U¾O§U†UŒU©UˆU„O§O¦Uˆ (O¬U‡Oa O§O±O²UŒO§O¨UŒ U…UˆO±UUˆU„UˆU˜US O§O³U¾O±U…)OŒ O±U†U¯‌O¢U…UŒO²UŒ U©O±UˆU…UˆU…O§UŒO³UŒU† A3 (O¬U‡Oa O§O±O²UŒO§O¨UŒ U©U…O¨UˆO¯ U¾O±UˆOaO§U…UŒU†) Uˆ OaO³Oa SCD (O¬U‡Oa O§O±O²UŒO§O¨UŒ U…UŒO²O§U† UO±O§U¯U…U†OaO§O³UŒUˆU† DNA ) O§U†O¬O§U… O´O¯. U‡U…U†U†UŒU† O¨O± O±UˆUŒ O­O¬U…UŒ O§O² U†U…UˆU†U‡ O¨U‡ O¹U†UˆO§U† U¯O±UˆU‡ O´O§U‡O¯OŒ O±UˆO´‌U‡O§UŒ U…O°U©UˆO± O§U†O¬O§U… U¯O±O¯UŒO¯. UŒO§UOaU‡ U‡O§: O§O³U¾O±U…‌U‡O§UŒ O¬O¯O§ O´O¯U‡ O§O² O·O±UŒU‚ O±UˆO´ HA-binding Uˆ Zeta O¨U‡ O·UˆO± U…O¹U†UŒ‌O¯O§O±UŒ U©O§U‡O´ O¯O± U…UŒO²O§U† U†O§U‡U†O¬O§O±UŒ‌U‡O§UŒ U…UˆO±UUˆU„UˆU˜UŒ Uˆ U©U…O¨UˆO¯ U¾O±UˆOaO§U…UŒU† O±O§ U†O´O§U† O¯O§O¯U†O¯ (05/0 P ). O§U…O§ OaU†U‡O§ O±UˆO´ Zeta U…UŒO²O§U† UO±O§U¯U…U†OaO§O³UŒUˆU† DNA O±O§ O¨U‡ O·UˆO± U…O¹U†UŒ‌O¯O§O±UŒ U©O§U‡O´ O¯O§O¯ (05/0 P ). U†OaUŒO¬U‡ U¯UŒO±UŒ: U‡O± O¯Uˆ O±UˆO´ HA- binding Uˆ Zeta U…UŒ‌OaUˆO§U†U†O¯ O§O³U¾O±U…‌U‡O§UŒ O¨O§ U…UˆO±UUˆU„UˆU˜US O·O¨UŒO¹UŒ Uˆ U…UŒO²O§U† U©U…O¨UˆO¯ U¾O±UˆOaO§U…UŒU† U©U…OaO± O±O§ O¬O¯O§ U©U†U†O¯. UˆU„UŒ U…UŒO²O§U† UO±O§U¯U…U†OaO§O³UŒUˆU† DNA OaU†U‡O§ O¯O± Zeta O¨U‡ O·UˆO± U…O¹U†UŒ‌O¯O§O±UŒ U©O§U‡O´ UŒO§UOaU‡ O§O³Oa. U„O°O§ U…UŒ‌OaUˆO§U† O¯O± O¨UŒU…O§O±O§U†UŒ U©U‡ O¯O§O±O§UŒ UO±O§U¯U…U†OaO§O³UŒUˆU† DNA O¨O§U„O§ U‡O³OaU†O¯OŒ O§O² Zeta O¬U‡Oa O¬O¯O§O³O§O²UŒ O§O³U¾O±U…‌U‡O§ O§O³OaUO§O¯U‡ U©O±O¯. UˆO§U˜U¯O§U† U©U„UŒO¯UŒ: O§O³UŒO¯ U‡USO§U„UˆO±UˆU†USUƒOŒ OaO²O±UŒU‚ O¯O±UˆU† O³USOaUˆU¾U„O§O³U…US O§O³U¾O±U…UŒ ( ICSI )OŒ U…UˆO±UUˆU„UˆU˜US O§O³U¾O±U…OŒ U¾O±UˆOaO§U…UŒU†OŒ UO±O§U¯U…U†OaO§O³UŒUˆU† DNA .

Journal Article
TL;DR: A diabetic man with sino-orbital mucormycosis whose treatment switched to posaconazole for 8 weeks because of renal failure due to amphotricine B and after clinical and radiological improvement he was discharged but 2 weeks later, he was admitted again because of severe headache and involvement of temporal artery with mucormYcosis established by biopsy.
Abstract: Normal 0 false false false EN-US X-NONE FA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} Abstract Background: Mucormycosis is a life threatening angioinvasive fungal infection that causes thrombosis and tissue necrosis, it often affects diabetic and immune compromised patients. Ophthalmic artery, cavernus sinus and internal carotid artery involvement have been reported. Treatment includes wide surgical debridement and antifungal agents that the newest of witch is posaconazole. Case Report: In this article we report a diabetic man with sino-orbital mucormycosis whose treatment switched to posaconazole for 8 weeks because of renal failure due to amphotricine B and after clinical and radiological improvement he was discharged ; but 2 weeks later, he was admitted again because of severe headache and involvement of temporal artery with mucormycosis established by biopsy. Key words: Mucormycosis, sinusitis, posaconazole, temporal artery, amphotricine B


Journal Article
TL;DR: Table Normal 0 false false false EN-US X-NONE FA MicrosoftInternetExplorer4 /* Style Definitions */ table.Normal
Abstract: Normal 0 false false false EN-US X-NONE FA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} U†U©UŒO¯U‡ U…U‚O¯U…U‡: U…O·O§U„O¹U‡‌UŒ O­O§O¶O± O¬U‡Oa OaO¹UŒUŒU† O¢O«O§O± U©UˆOaO§U‡ U…O¯Oa Uˆ O¨U„U†O¯ U…O¯Oa U…OµO±U O¢O¨ O§U†U¯UˆO± Uˆ O¢O¨ O§U†O§O± O¨O± O¹U…U„U©O±O¯ O§U†O¯UˆOaU„UŒUˆU… O¹O±UˆU‚ O¯O± U†UˆO¬UˆO§U†O§U† U…O¨OaU„O§ O¨U‡ O³U†O¯O±U… U…OaO§O¨UˆU„UŒU© O§U†O¬O§U… O´O¯U‡ O§O³Oa. O±UˆO´ U‡O§: O§UŒU† U…O·O§U„O¹U‡ U©U‡ O§O² U†UˆO¹ U©U†OaO±U„ O´O¯U‡‌UŒ OaOµO§O¯UUŒ O¨O§U„UŒU†UŒ O¨UˆO¯OŒ O¯O± O³O§U„ 2008 O±UˆUŒ 30 U†UˆO¬UˆO§U† 15-12 O³O§U„U‡ U©U‡ U…O¨OaU„O§ O¨U‡ O³U†O¯O±U… U…OaO§O¨UˆU„UŒU© (O·O¨U‚ OaO¹O±UŒU UO¯O±O§O³UŒUˆU† O¨UŒU†‌O§U„U…U„U„UŒ O¯UŒO§O¨Oa) O¨UˆO¯U†O¯ O§U†O¬O§U… O´O¯U‡ O§O³Oa. U¾O³ O§O² O§U†O¬O§U… OaO³Oa‌U‡O§UŒ O§UˆU„UŒU‡ U©UˆO¯U©O§U† O¨U‡ OµUˆO±Oa OaOµO§O¯UUŒ O¨U‡ O¯Uˆ U¯O±UˆU‡ U…O³O§UˆUŒ OaU‚O³UŒU… O´O¯U†O¯OŒ U¯O±UˆU‡ O§UˆU‘U„ O±UˆO²O§U†U‡ cc/kg 18 O¢O¨ O§U†U¯UˆO± Uˆ U¯O±UˆU‡ O¯UˆU… O±UˆO²O§U†U‡ cc 240 O¢O¨ O§U†O§O± O¨U‡ U…O¯Oa UŒU© U…O§U‡ U…OµO±U U©O±O¯U†O¯OŒ UˆO§U©U†O´ O´O±UŒO§U† O¨O§O²UˆUŒUŒ OaUˆO³O· O³UˆU†UˆU¯O±O§UUŒ high-resolution B-mode O§U†O¯O§O²U‡‌U¯UŒO±UŒ O´O¯. O¯O± O­O§U„Oa‌U‡O§UŒ O²UŒO± O³UˆU†UˆU¯O±O§UUŒ O§U†O¬O§U… O´O¯: O¯O± O­O§U„Oa O§O³OaO±O§O­Oa O§U†O¯O§O²U‡‌UŒ U¾O§UŒU‡‌UŒ O´O±UŒO§U† O¨O§O²UˆUŒUŒ ( BBD: Basal Brachial Dimension ) OŒ 90-30 O«O§U†UŒU‡ O¨O¹O¯ O§O² O¨O§O² U©O±O¯U† O¨O§O²UˆO¨U†O¯ O¯O± U¾O§O³O® O¨U‡ U¾O±O®UˆU†UŒ UˆO§U©U†O´UŒOŒ O§OaO³O§O¹ UˆO§O¨O³OaU‡ O¨U‡ O§U†O¯UˆOaU„UŒUˆU… ( EDD: Endothelium -Dependent Dilation ) Uˆ UŒO§ O§OaO³O§O¹ UˆO§O¨O³OaU‡ O¨U‡ O¬O±UŒO§U† ( FMD: Flow Mediated Dilation ) Uˆ O¨O§O± O¯UŒU¯O± O¯O± O­O§U„Oa O§O³OaO±O§O­Oa Uˆ O³U‡ OaO§ U†U‡O§O± O¯U‚UŒU‚U‡ U¾O³ O§O² O¯O±UŒO§UOa 400 U…UŒU©O±Uˆ‌U¯O±U… U†UŒOaO±UˆU¯U„UŒO³UŒO±UŒU† O²UŒO± O²O¨O§U†UŒ ( TNG ) U©U‡ O§OaO³O§O¹ OoUŒO± UˆO§O¨O³OaU‡ O¨U‡ O§U†O¯UˆOaU„UŒUˆU… ( EID: Endothelium Independent Dilation ) O±O§ U†O´O§U† U…UŒ‌O¯U‡O¯. UŒO§UOaU‡ U‡O§: O³UˆU†UˆU¯O±O§UUŒ U‚O¨U„ Uˆ U†U‡O§O± O³O§O¹Oa U¾O³ O§O² U†UˆO´UŒO¯U† O¢O¨ U…UŒUˆU‡ Uˆ UŒU© U…O§U‡ U¾O³ O§O² U†UˆO´UŒO¯U† U…U†O¸U… O¢O¨ U…UŒUˆU‡ O¬U‡Oa O¨O±O±O³UŒ O§O«O± U©UˆOaO§U‡ U…O¯Oa Uˆ O¨U„U†O¯ U…O¯Oa O¢U† O§U†O¬O§U… O´O¯. FMD O¯O± O«O§U†UŒU‡‌U‡O§UŒ 30 Uˆ 90 Uˆ U¾O³ O§O² TNG O¨U‡ O·UˆO± U…O¹U†UŒ‌O¯O§O±UŒ O¨O¹O¯ O§O² U†U‡O§O± O³O§O¹Oa O§O² U…OµO±U O¢O¨ U…UŒUˆU‡ O¯O± U‡O± O¯Uˆ U¯O±UˆU‡ O¨U‡O¨UˆO¯ U¾UŒO¯O§ U©O±O¯. U‡U…U†U†UŒU† FMD O¯O± O«O§U†UŒU‡‌U‡O§UŒ 90-30 Uˆ U¾O³ O§O² TNG Uˆ U†UŒO² O¨O¹O¯ O§O² U…OµO±U UŒU© U…O§U‡U‡ O¢O¨ U…UŒUˆU‡‌U‡O§ U†UŒO² O¨U‡ O·UˆO± U…O¹U†UŒ‌O¯O§O±UŒ O§UO²O§UŒO´ UŒO§UOa UˆU„UŒ BBD UU‚O· U¾O³ O§O² UŒU© U…O§U‡ U†UˆO´UŒO¯U† O¢O¨ O§U†U¯UˆO± O¨U‡ O·UˆO± U…O¹U†UŒ‌O¯O§O±UŒ OaUO§UˆOa O¯O§O´Oa. U†OaUŒO¬U‡ U¯UŒO±UŒ: UŒO§UOaU‡‌U‡O§UŒ U…O§ U¾UŒO´U†U‡O§O¯ U…UŒ‌U©U†O¯ U©U‡ U…OµO±U O±UˆO²O§U†U‡‌UŒ U…UˆO§O¯ OoU†UŒ O§O² O¢U†OaUŒ‌O§U©O³UŒO¯O§U† U…UŒ‌OaUˆO§U†O¯ UˆO¶O¹UŒOa O¹U…U„U©O±O¯ O§U†O¯UˆOaU„UŒO§U„ O±O§ O¯O± U†UˆO¬UˆO§U†O§U† U…O¨OaU„O§ O¨U‡ O³U†O¯O±U… U…OaO§O¨UˆU„UŒU© O¨U‡O¨UˆO¯ O¨O®O´O¯. UˆO§U˜U¯O§U† U©U„UŒO¯UŒ: O³U†O¯O±U… U…OaO§O¨UˆU„UŒU©OŒU©UˆO¯U©O§U†OŒ UˆO§U©U†O´ O¹O±UˆU‚UŒOŒ O¢U†OaUŒ‌O§U©O³UŒO¯O§U†‌‌U‡O§.



Journal Article
TL;DR: Although neither of the ratios had perfect or high reliability with regard to the subject of the study, it seems that the accuracy of Youm index is higher.
Abstract: IntroductionCarpal height is a radiographic ratio with clinical significance in rheumatologic diseases and Kienbock disease, which is measured with different methods. The purpose of this study is assessment of two popular methods of measurement of this angle with respect to inter- and intraobserver variabilities.Materials and methodsGood-quality photographs were made of 20 radiograms and two experienced orthopedists, in two separate occasions measured the length of third metacarpal, the longest length of capitate, and the distance between the base of third metacarp to the articular surface of the radius. The remainder of the calculations was made by computer.ResultsIntraobserver reliability of the Youm and Nattrass ratios was calculated as high and fair, respectively. With regard to interobserver reliability, the accuracy of both indices was poor. Intra- and interobserver agreement for detection of collapse of the wrist was substantial for Youm ratio and fair to moderate for Nattrass ratio. The ratios had poor agreement with each other with regard to detection of collapse of the wrist joint.ConclusionAlthough neither of the ratios had perfect or high reliability with regard to the subject of the study, it seems that the accuracy of Youm index is higher.

Journal Article
TL;DR: The present results suggest that learning and memory is affected under the condition of morphine addiction, but treadmill running prevents these effects, leading to the possibility that treadmill running is helpful in the prevention and alleviation of the cognitive decline in opioid addiction.
Abstract: Background:Previous studies have shown an association between opioid addiction and impairments in learning and memory. Due to the fact that exercise has positive effects on many physiological systems, including the central nervous system, the present study, evaluated the effects of treadmill running on learning and memory in opioid addicted rats. Method: Forty two male wistar rats (300-350 g) were divided into four groups, the control group, the control-exercise group, the morphine group and the morphine-exercise group. In Morphine-treated groups, Morphine was injected intraperitonealy as follow: first 3 days 10 mg/kg, next 3 days 20 mg/kg and during the last 3 days 40 mg/kg .In exercise groups, the exercise program was treadmill running at 17 meters per minute (m/min) at 7° inclination for 60 minutes per day (min/day), 7 days/week, for 3 months. Passive avoidance learning and memory was investigated by shuttle box in the rats after 3 months of addiction and exercise. Findings: Data showed that learning and memory was impaired significantly in the morphine-rest group with respect to the control group; however, exercise has improved learning and memory in the morphine-exercise group and in the control-exercise group. Results: The present results suggest that learning and memory is affected under the condition of morphine addiction, but treadmill running prevents these effects. The data correspond to the possibility that treadmill running is helpful in the prevention and alleviation of the cognitive decline in opioid addiction. Key words:Treadmill running, Learning and memory, Morphine, Rat.

Journal Article
TL;DR: With respect to successful tracheal intubation of all patients in this trial and the usefulness of disposable laryngoscopes to prevent cross-contamination between patients and regardless of significant difference in lARYngoscopic conditions between disposable and metalic blades, disposable lariesgoscope can be used under normal intubating conditions in pediatrics.
Abstract: Background: Laryngoscopes are the potential cause of cross-contamination between patients. A considerable way to prevent this problem is to use of disposable laryngoscope’s blades. This study was designed to evaluate laryngoscopic conditions in pediatrics with disposable and metalic Macintosh blades. Methods: 152 children scheduled for elective surgery aged 3-12 years were enrolled in this randomized clinical trial. After induction of anesthesia, anesthesiologist intubated the patients with one of two kinds of laryngoscope’s blades (disposable or metalic Macintosh). During laryngoscopy and tracheal intubation, glottic view, brightness of laryngoscopic field, time of intubation and satisfaction degree of anesthesiologist was recorded. Findings: All patients were successfully intubated. There was significant difference between disposable and metalic Macintosh blades with respect to time of intubation and brightness of laryngoscopic field. Grade I of laryngoscopy was more frequent in metalic group compared to disposable group (83% vs. 49%) Anesthesiologist satisfaction was significantly improved during laryngoscopy with metalic Macintosh blade. Conclusion: With respect to successful tracheal intubation of all patients in this trial and the usefulness of disposable laryngoscopes to prevent cross-contamination between patients and regardless of significant difference in laryngoscopic conditions between disposable and metalic blades, disposable laryngoscopes can be used under normal intubating conditions in pediatrics. Key words: Pediatric, Disposable laryngoscope, Anesthesia, Children.



Journal Article
TL;DR: In this article, the relationship between albuminuria and coronary artery disease severity has been assessed with bivariate correlation methods and multivariate analysis, and there was no correlation between urine Pr/Cr ratio and CAD severity.
Abstract: BACKGROUND :Albuminuria is one of the abnormalities which occur in diabetics. Different studies have shown its relationship with cardiovascular diseases but few studies have been performed to show the relationship between albuminoria level and coronary artery disease (CAD) severity. This study was designed to asses the relationship between albuminuria and coronary artery disease severity. METHODS: In this cross-sectional study, the 164 Non-Insulin Dependent Diabetes Mellitus patients with angina pectoris who hospitalized for diagnostic or therapeutic angiography in Isfahan Chamran hospital were included. Urine Pr/Cr ratio has been calculated in all patients, using the first sample of morning urine. The standard angiography video has been assessed by three cardiologists through Seldinger method. CAD score has been given from 0 to 21 based on Extent method. The relationship between CAD severity and urine Pr/Cr ratio has been assessed with bivariate correlation methods and multivariate analysis. RESULTS: In 164 patients (males = 80 & females = 84) morning urine protein mean was 22.77 ± 30.99 and morning urine creatinin mean was 0.07 ± 0.04. Urine Pr/Cr ratio was 760.94 ± 401.56 mg/g and its median was 181.02. The CAD score was equal to 13.34 ± 6.24. There was no correlation between urine Pr/Cr ratio and CAD severity (P = 0.778, r = 0.022). In multivariate analysis , increased urine Pr/Cr ratio led to increased CAD severity by control of the age, FBS, gender, Captopril use, history of HTN and hyperlipidemia variables (P = 0.021). CONCLUSION : The amount of albuminuria which measured based on morning urine sample Pr/Cr ratio may be an independent risk factor for severity of CAD and can predict it. These findings signify the importance of albuminuria diagnosis and treatment. Key words: Severity, Coronary artery disease, Albuminuria, Angiography.

Journal Article
TL;DR: Intratympanic injection of steroid is one effective modality in treatment of sudden sensorineural hearing loss in cases with no response to standard systemic therapy and can improve the hearing level of patients while its complication rate is low.
Abstract: Background: Intratympanic steroid injection is an effective method in treatment of sudden sensorineural hearing loss in cases resisted to systemic therapy. The purpose of this study was to determine the efficacy of intratympanic injection. Methods: This case-series study was carried out on fifteen patients with sudden sensorineural hearing loss that had failed systemic therapy. Audiometric evaluation (PTA) performed before and after treatment and intratympanic dexametasone injection performed and the amount of improvement evaluated. Data Analysis was done using SPSS11. Findings: In male patients, 33.3% partial and 33.3% complete improvement and in female patients, 18.6% partial and 50% complete improvement was reported. In cases with lower degrees of hearing loss, total improvement was 66.7%; also earlier time of treatment had better results. Conclusion: Intratympanic injection of steroid is one effective modality in treatment of sudden sensorineural hearing loss in cases with no response to standard systemic therapy. It can improve the hearing level of patients while its complication rate is low and as degree of hearing loss increases the results decrease earlier treatment have a better results. Key words:Sudden sensorineunal hearing loss, Intratympanic steroid injection.