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JournalISSN: 0022-2836

Journal of Molecular Biology 

Elsevier BV
About: Journal of Molecular Biology is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): DNA & Protein structure. It has an ISSN identifier of 0022-2836. Over the lifetime, 33148 publications have been published receiving 2829194 citations. The journal is also known as: J Mol Biol & J. Mol. Biol..
Topics: DNA, Protein structure, RNA, Gene, Binding site


Papers
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Journal ArticleDOI
TL;DR: A new approach to rapid sequence comparison, basic local alignment search tool (BLAST), directly approximates alignments that optimize a measure of local similarity, the maximal segment pair (MSP) score.

88,255 citations

Journal ArticleDOI
TL;DR: This paper describes a method of transferring fragments of DNA from agarose gels to cellulose nitrate filters that can be hybridized to radioactive RNA and hybrids detected by radioautography or fluorography.

30,291 citations

Journal ArticleDOI
TL;DR: A computer program that progressively evaluates the hydrophilicity and hydrophobicity of a protein along its amino acid sequence has been devised and its simplicity and its graphic nature make it a very useful tool for the evaluation of protein structures.

21,921 citations

Journal ArticleDOI
TL;DR: A comparative protein modelling method designed to find the most probable structure for a sequence given its alignment with related structures, which is automated and illustrated by the modelling of trypsin from two other serine proteinases.

12,386 citations

Journal ArticleDOI
TL;DR: A computer adaptable method for finding similarities in the amino acid sequences of two proteins has been developed and it is possible to determine whether significant homology exists between the proteins to trace their possible evolutionary development.

11,844 citations

Performance
Metrics
No. of papers from the Journal in previous years
YearPapers
2023201
2022498
2021438
2020424
2019346
2018355