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JournalISSN: 0165-5728

Journal of Neuroimmunology 

Elsevier BV
About: Journal of Neuroimmunology is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Multiple sclerosis & Experimental autoimmune encephalomyelitis. It has an ISSN identifier of 0165-5728. Over the lifetime, 8844 publications have been published receiving 327030 citations. The journal is also known as: JNI.


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Journal ArticleDOI
TL;DR: The role of specific cell types including leukocytes, endothelium, glia, microglia, the extracellular matrix and neurons, and mediators produced by inflammatory cells such as cytokines, chemokines, reactive oxygen species and arachidonic acid metabolites are reviewed.

1,096 citations

Journal ArticleDOI
TL;DR: Since BV-2 cells retain most of the morphological, phenotypical and functional properties described for freshly isolated microglial cells, it can be concluded that J2 virus infection has resulted in the immortalization of active microglia cells.

952 citations

Journal ArticleDOI
TL;DR: Electron microscopy data suggest that amyloid deposition may precede the activation of microglia and that HLA-DR-positive reactivemicroglia embedded in their core may be in intimate contact with amyloids fibrils.

915 citations

Journal ArticleDOI
TL;DR: While inflammation has been thought to arise secondary to degeneration, recent experiments demonstrated that inflammatory mediators may stimulate APP processing by upregulation of beta secretase 1 and therefore are able to establish a vicious cycle.

895 citations

Journal ArticleDOI
TL;DR: The glial fibrillary acidic protein (GFA protein or GFAP) is the major protein constituent of glial intermediate filaments in differentiated fibrous and protoplasmic astrocytes of the central nervous system.

690 citations

Performance
Metrics
No. of papers from the Journal in previous years
YearPapers
202393
2022188
2021240
2020232
2019190
2018182