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Showing papers in "Journal of Surgical Research in 1974"




Journal ArticleDOI
TL;DR: The results suggest that the Ca 2+ current contribution to the normal action potential is depressed in a similar fashion to that of the catecholamine- or methylxanthine-induced responses, suggesting that the production and/or maintenance of Ca 2- channels are energy dependent.

106 citations


Journal ArticleDOI
TL;DR: It is suggested that systemic antibiotics have no role in attempting to decrease the bacterial count in a granulating wound and the fibrin base of a granulation wound may prevent adequate antibiotic penetration into the wound.

97 citations


Journal ArticleDOI
TL;DR: Tumor response to chemotherapy was not abolished, surgical morbidity and mortality were minimized, and the undesirable side effects of radiotherapy and chemotherapy were reduced.

81 citations


Journal ArticleDOI
TL;DR: It is demonstrated that ureteral reflux from ileal conduits produces histologic evidence of pyelonephritis, and colonic conduits, by preventing reflux of infected urine, reduce the frequency of Pyel onephritis and offer definite advantages for long-term urinary diversion.

80 citations


Journal ArticleDOI
TL;DR: The present studies demonstrate the feasibility of an approach designed for the large scale isolation and transplantation of islets in man, and reveal a significant purification of islet from acinar tissue.

77 citations


Journal ArticleDOI
TL;DR: Mongrel dogs were subjected to two experimental forms of hepatic damage, 2,4-dimethylnitrosamine ingestion, and end-to-side portacaval shunt and gave an amino acid pattern much more similar to that found in man.

73 citations


Journal ArticleDOI
TL;DR: Substantial evidence supporting the use of mannitol as a preventive measure in the clinical setting where infrarenal aortic occlusion must be employed is presented.

63 citations


Journal ArticleDOI
E.F. Hirsch1, T. Nakajima1, G. Oshima1, E.G. Erdös1, C.M. Herman1 
TL;DR: The results suggest the liberation of bradykinin in septic shock, and the level or activity of plasma kallikrein, kininase I (carboxypeptidase N), trypsin and kall Kikrein inhibitors.

60 citations




Journal ArticleDOI
TL;DR: P pH and manometric measurements across the DES were obtained on 159 patients and it was concluded that symptoms are an unreliable guide to the presence or absence of gastroesophageal reflux as determined by the standard acid reflux test (SART).

Journal Article
TL;DR: From the Surgical Laboratory, Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80521, a thesis submitted by the first author in partial fulfillment of the requirements for the M.S. degree in Surgery.

Journal ArticleDOI
TL;DR: Lumb as mentioned in this paper submitted a thesis submitted by the first author in partial fulfillment of the requirements for the M.S. degree in Surgery, which was accepted by the University of Nairobi, Kenya.

Journal ArticleDOI
TL;DR: It is found that intraperitoneal Betadine solution is apparently safe to rats at doses of 2.5 ml/kg or less as regards acute and chronic toxicity.


Journal ArticleDOI
TL;DR: Significant resistance to tumor growth was demonstrated by animals immune to MCA-R and by animalsimmune to second trimester fetal tissue, and immunological similarity between fetal antigen and tumor associated transplantation antigens is suggested.

Journal ArticleDOI
TL;DR: Pluronic F-68 has been previously shown to increase the microcirculation in the mesentery and to increase urinary output in experimental hemorrhagic shock, but these effects are apparently not related to a central, inotropic effect, but to its peripheral rheological properties.

Journal ArticleDOI
TL;DR: Sudden diversion of portal blood from the healthy rat liver causes a transient loss in body weight and specific atrophy of the liver in accord with the decrease in total liver blood flow caused by the shunt, but the liver of an Eck fistula rat clearly retains its potential to regenerate.

Journal ArticleDOI
TL;DR: Thirty-two extremities in 30 patients with various venous disorders were comparatively studied by clinical examination, impedence phlebography, Doppler examination, and 99Tc isotopic venography for the presence of venous thrombosis.

Journal ArticleDOI
TL;DR: The younger animals showed significant enlargement of the adrenal glands and also enlargements of heart and kidneys suggesting work hypertrophy of these organs.

Journal ArticleDOI
TL;DR: It is suggested that persistent abnormal myocardial carbohydrate metabolism and low levels of high energy nucleotides prevent contractile recovery following normothermic anoxic arrest and reperfusion.


Journal ArticleDOI
TL;DR: The results of this experiment indicate that mediolateral plication of the paralyzed diaphragm improves vital capacity and maximum breathing capacity up to 4 wk postoperative.

Journal ArticleDOI
TL;DR: In this paper, animals were subjected to pulmonary contusion and hemorrhage (30 mlg/kg), and blood volume was restored with plasma equal to and three times the blood volume and Ringer's lactate solution in a volume three times of shed blood.

Journal ArticleDOI
TL;DR: Observations that PGE may be involved in the control of cell proliferation in vitro are extended by additional studies using HT-29, a derivative of human adenocarcinoma.

Journal ArticleDOI
TL;DR: It is suggested that arterial damage occurring during organ perfusion prior to transplantation increases significantly the production of obliterative vascular lesions in arteries that are demonstrable with the scanning electron microscope.

Journal ArticleDOI
TL;DR: In this paper, Sutilains (Travase) enzymatic debridement has been evaluated in the noninfected and the Pseudomonas-infected experimental burn wound and the incorporation of Sulfamylon or silver sulfadiazine 1% with sutilains did not protect against burn wound sepsis and death.

Journal ArticleDOI
TL;DR: Early results from excision with the CO2 laser are most encouraging and efforts with this modality of treatment are being expanded.