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Showing papers in "Journal of the American College of Cardiology in 1992"


Journal ArticleDOI
TL;DR: Common clinical and ECG features define a distinct syndrome in this group of patients with recurrent episodes of aborted sudden death unexplainable by currently known diseases, not explainable by electrolyte disturbances, ischemia or structural heart disease.

3,075 citations


Journal ArticleDOI
TL;DR: Normalizations of left ventricular mass for height or body surface area introduce artifactual relations of indexed ventricularmass to body size and errors in estimating the impact of overweight, which are avoided and variability among normal subjects is reduced.

1,673 citations


Journal ArticleDOI
TL;DR: Correspondence of left ventricular mass in concentric remodeling appeared to reflect offsetting by volume "underload" of the effects of pressure overload, whereas eccentric hypertrophy was associated with concomitant pressure and volume overload.

1,519 citations


Journal ArticleDOI
TL;DR: The severity of vessel injury strongly correlated with neointimal thickness and percent diameter stenosis and Neointimal proliferation resulting from a given wire was related to injury severity in adjacent wires, suggesting an interaction among effects at injured sites.

1,202 citations


Journal ArticleDOI
TL;DR: Observations support the formulation of a neurohormonal hypothesis of heart failure and provide the basis for the development of novel therapeutic strategies in the next decade.

1,008 citations


Journal ArticleDOI
TL;DR: Congestive heart failure is a common problem in the U.S., with significant prevalence and mortality, both of which increase with advancing age, and estimates suggest that between 1 and 2 million adults are affected.

836 citations


Journal ArticleDOI
TL;DR: In this paper, the authors found that younger patients with an isolated coronary artery anomaly are significantly more likely than older patients (≥ 30 years old) to die suddenly (62% vs. 12%, p = 0.0001) or during exercise.

765 citations


Journal ArticleDOI
TL;DR: The data suggest that in patients with atrial fibrillation and a history of congestive heart failure, the risk of antiarrhythmic drug therapy may outweigh the potential benefit of maintaining sinus rhythm.

618 citations


Journal ArticleDOI
TL;DR: An alternative hypothesis for restenosis is based on observations in the porcine coronary injury model, which assumes thrombus assumes a major role in restonosis by providing an absorbable matrix into which smooth muscle cells proliferate.

582 citations


Journal ArticleDOI
TL;DR: Positron emission tomographic myocardial viability imaging appears to identify patients at increased risk of having an adverse cardiac event or death, and patients with impaired left ventricular function and positron emissiontomographic evidence for jeopardized myocardium appear to have the most benefit from a revascularization procedure.

505 citations


Journal ArticleDOI
TL;DR: A history of peripheral or cerebrovascular disease, presence of aortic calcification, cardiac risk factors, age and duration of cardiopulmonary bypass did not predict stroke, and patients with protruding atheromas with mobile components were at highest risk.

Journal ArticleDOI
TL;DR: The velocity of flow propagation during early filling seems to be highly dependent on the left ventricular relaxation rate and could be an important tool in studying diastolic function.

Journal ArticleDOI
TL;DR: In this paper, the local vascular response to intraarterial infusions of graded concentrations of acetylcholine and nitroglycerin was studied in the superficial femoral artery of 19 patients with congestive heart failure (New York Heart Association classes I to IV) and 6 age-matched normal control subjects.

Journal ArticleDOI
TL;DR: There is a high prevalence of aortic root enlargement in patients with a bicuspid aorti valve that occurs irrespective of altered hemodynamics or age, and these findings support the hypothesis that bic Suspid aORTic valve and aortIC root dilation may reflect a common developmental defect.

Journal ArticleDOI
TL;DR: Patients with pulmonary hypertension at risk of developing fatal right heart failure after heart transplantation are screened by measuring rest right heart pressures and the response to nitroprusside, and the influence of pretransplantation right heart catheterization data on outcome after transplantation was analyzed.

Journal ArticleDOI
TL;DR: Improved performance of the voltage-duration products for the detection of left ventricular hypertrophy was independent of test partition selection and may approach or exceed the performance of more complex multiple regression analyses.

Journal ArticleDOI
TL;DR: Data indicate that transformation of left ventricular shape (increased chamber sphericity) is the most likely substrate for the development of functional mitral regurgitation in patients with chronic heart failure.

Journal ArticleDOI
TL;DR: Estrogen affects endothelium-dependent coronary dilation within 20 min of administration and may have rapid direct effects on the vascular endothelia.

Journal ArticleDOI
TL;DR: Cor coronary artery injury in swine with either balloon inflation or stenting leads to intimal smooth muscle cell proliferation similar to that seen in human restenosis, which appears to be greater after stenting than after balloon injury.

Journal ArticleDOI
TL;DR: Prophylactic anticoagulation is pivotal in patients undergoing elective direct current cardioversion for atrial fibrillation, even those with atrialfibrillation of less than 1 week's duration.

Journal ArticleDOI
TL;DR: Measurement of noninvasive impedance by this technique provides an accurate and repeatable assessment of mean and pulsatile cardiac load.

Journal ArticleDOI
TL;DR: Examination of post-treadmill stress echocardiograms in 150 consecutive patients who also underwent cardiac catheterization and in 29 normal persons at low risk for coronary artery disease found that age, gender, body weight and image quality did not significantly influence the accuracy of exercise eChocardiography.

Journal ArticleDOI
TL;DR: Dobutamine stress echocardiography has high sensitivity and specificity for the detection and localization of coronary artery disease and detection of stenosis in individual coronary arteries is improved in those lesions with a minimal lumen diameter less than 1 mm.

Journal ArticleDOI
TL;DR: Although prolonged balloon inflations and intracoronary stents may improve outcome after abrupt vessel closure, the cumulative risk of morbidity or mortality remains significant and mandates investigation into improved strategies for its prevention and treatment.

Journal ArticleDOI
TL;DR: Stepwise discriminant analysis indicates that smoking, hypertension, decreased apolipoprotein A-I, increased apoliprotein B, increased Lp(a) and diabetes are all significant factors in descending order of importance in distinguishing patients with coronary artery disease from normal control subjects.

Journal ArticleDOI
TL;DR: Alteplase resulted in a greater and faster improvement of the angiographic and hemodynamic variables compared with heparin, and the high frequency of bleeding observed with altePlase in this trial suggests that patients should be carefully selected before thrombolytic therapy is given.

Journal ArticleDOI
TL;DR: It is proposed that these are therapeutic goals that may reduce cardiovascular morbidity and mortality and the primary goal of therapy should be to preserve or restore tissue structure and function.

Journal ArticleDOI
TL;DR: The detection of coronary calcification by ultrafast computed tomographic scanning is highly predictive of the presence of histopathologic coronary disease, but the use of this technique to define the extent of coronary disease may be limited.

Journal ArticleDOI
TL;DR: It is concluded that a catheter ablation procedure using radiofrequency energy can be performed on accessory pathways in all locations and can be considered as an alternative to lifelong medical therapy in any patient with symptomatic accessory pathway-mediated tachycardia.

Journal ArticleDOI
TL;DR: Automatic boundary detection based on quantitative assessment of tissue acoustic properties permits on-line quantitation of ventricular cavity areas and indexes of function and more than 70% of patients could be studied adequately with the approach developed.