Showing papers in "Journal of the American College of Cardiology in 1999"
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2,115 citations
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TL;DR: Although CHF cases with normal LV systolic function have a lower mortality risk than cases with reduced LVEF, they have a fourfold mortality risk compared with control subjects who are free of CHF.
1,370 citations
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TL;DR: The approaches described in this statement can be used for guidance at several levels of primary prevention; however, the statement does not attempt to specifically link risk assessment to treatment guidelines for particular risk factors, but provides critical background information that could be used in the development of new treatment guidelines.
1,276 citations
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TL;DR: Coronary Angiography: A Treatise on Morbidity and Mortality 1757-1764.
1,036 citations
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TL;DR: Ventricular pacing causes a threefold difference in myofiber work within the left ventricular (LV) wall, which appears large enough to regard local myocardial function as an important determinant for abnormalities in perfusion, metabolism, structure and pump function during asynchronous electrical activation.
694 citations
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TL;DR: In Japanese children, INVM can be found by screening examinations at asymptomatic stage, and it might have a longer dinical course with gradually depressed left ventricular function and restrictive hemodynamics, implying that INVM is a distinctive clinical entity with a heterogeneous genetic background.
682 citations
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TL;DR: Hyperglycemia in response to oral glucose loading rapidly suppresses endothelium-dependent vasodilation, probably through increased production of oxygen-derived free radicals, and these findings strongly suggest that prolonged and repeated post-prandial hyper glycemia may play an important role in the development and progression of atherosclerosis.
672 citations
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TL;DR: It is important that the medical profession play a significant role in critically evaluating the use of diagnostic procedures and therapies in the management or prevention of disease states.
667 citations
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TL;DR: In this article, a coronary heart disease is the leading cause of death in the industrialized world and new treatments focus on death as a primary end point, which is intuitively appealing to attempt to better understand the association.
578 citations
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TL;DR: The AMISTAD trial as discussed by the authors was designed to test the hypothesis that adenosine as an adjunct to thrombolysis would reduce myocardial infarct, and the results showed that the hypothesis was true.
546 citations
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TL;DR: This review deals with the clinical, basic and genetic aspects of a recently highlighted form of idiopathic ventricular fibrillation known as the Brugada syndrome and attempts to correlate the electrocardiographic manifestations with cellular and ionic heterogeneity known to exist within the heart under normal and pathophysiologic conditions so as to identify the cellular basis and thus potential diagnostic and therapeutic approaches.
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TL;DR: Enhanced external counterpulsation reduces angina and extends time to exercise-induced ischemia in patients with symptomatic CAD and was relatively well tolerated and free of limiting side effects in most patients.
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TL;DR: First epidemiologic evidence that endotoxemia constitutes a strong risk factor of early atherogenesis in subjects with chronic or recurrent bacterial infections and a link in the association between cigarette smoking and atherosclerotic disease is yielded.
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TL;DR: Dual-chamber pacing with rate-drop response reduces the likelihood of syncope in patients with recurrent vasovagal syncope and fulfilled the prespecified criteria for early termination of the study.
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TL;DR: The endothelium plays a key role in vascular homeostasis through the release of a variety of autocrine and paracrine substances and is antiatherogenic because of effects that include inhibition of platelet aggregation and adhesion, smooth and hardening.
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TL;DR: There is a close dependency between warfarin dosage and fetal complications in patients with mechanical heart valves requiring long-term anticoagulant therapy.
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TL;DR: In this article, the safety and effectiveness of laser-assisted pacemaker lead extraction with the excimer sheath in comparison to non-laser lead extraction was evaluated in 301 patients with 465 chronically implanted pacemaker leads.
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TL;DR: Tailored thrombolytic regimens compatible with subsequent interventions lead to more frequent early recanalization (before cath arrival), which facilitates greater LV function preservation with no augmentation of adverse events.
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TL;DR: The effects of albuterol on IP(DVP) are mediated in part through the nitric oxide pathway and are impaired in patients with type II diabetes.
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TL;DR: Measurement of suitable markers of thrombogenesis might prove to be valuable in identifying "high risk" patients and in determining the nature, duration and intensity of such treatment, and further information is needed on the predictive value of various markers of hypercoagulability in patients with heart failure.
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TL;DR: Preprocedural CRP level, an easily measurable marker of acute phase response, is a powerful predictor of both early and late outcome in patients undergoing single vessel PTCA, suggesting that early complications and clinical restenosis are markedly influenced by the preprocesural degree of inflammatory cell activation.
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TL;DR: F Forced diuresis with intravenous crystalloid, furosemide, and mannitol if hemodynamics permit, beginning at the start of angiography provides a modest benefit against contrast-induced nephropathy provided a high urine flow rate can be achieved.
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TL;DR: Intravenous nicorandil in conjunction with coronary angioplasty is associated with better functional and clinical outcomes compared to angiopLasty alone in patients with an anterior AMI, and myocardial contrast echocardiography findings imply that an improvement in microvascular function with nicor andil may be attributable to this better outcome.
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TL;DR: This study indicates that digoxin and diltiazem, as single agents at the doses tested, are least effective for controlling ventricular rate in atrial fibrillation during daily activity.
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TL;DR: Patients with substantial viability on DSE demonstrated improvement in LVEF and NYHA functional class after revascularization; viability was also associated with a favorable prognosis afterRevascularization.
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TL;DR: Observational assessments reveal that stable chest pain patients who undergo a more aggressive diagnostic strategy have higher diagnostic costs and greater rates of intervention and follow-up costs.
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TL;DR: Clinical benefits with PRA not explained by LDL reductions may be the result of an independent action of PRA on eNOS activation, but SIM is much less effective.
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TL;DR: A distinct cardiac disorder linked to chromosome 1q42-q43 causes exercise-induced polymorphic ventricular tachycardia in structurally normal hearts and is highly malignant.