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Showing papers in "Journal of the American College of Cardiology in 2001"


Journal ArticleDOI
TL;DR: The findings suggest that the currently used equation for predicting maximal heart rate in older adults underestimates HRmax, which would have the effect of underestimating the true level of physical stress imposed during exercise testing and the appropriate intensity of prescribed exercise programs.

2,924 citations



Journal ArticleDOI
TL;DR: The American College of Cardiology (ACC) and the American Heart Association (AHA) first published guidelines for the evaluation and management of heart failure (HF) in 1995, and since that time, a great deal of progress has been made in the development of both pharmacological and nonpharmacological approaches to treatment for this common, costly, disabling, and generally fatal disorder.

1,829 citations


Journal ArticleDOI
TL;DR: A novel cardiomyopathy with transient apical ballooning, but without coronary artery stenosis, that mimics acute myocardial infarction was reported, and one died suddenly during follow-up.

1,551 citations



Journal ArticleDOI
TL;DR: The extraordinary advances in cardiac surgery, intensive care, and noninvasive diagnosis over the last 50 years have led to an enormous growth in the U.S. and throughout the world in the number of adults with congenital heart disease.

1,266 citations


Journal ArticleDOI
TL;DR: It was found that RVEF was preserved in some patients with pulmonary hypertension, and that the prognosis of these patients was similar to that of the patients with normal PAP, which emphasize the necessity of combining the right heart hemodynamic variables with a functional evaluation of the RV when trying to define the individual risk of patients with heart failure.

1,200 citations


Journal ArticleDOI
TL;DR: When two stents with different design are compared, the stent with thinner struts elicits less angiographic and clinical restenosis than the thicker-strut stent.

925 citations


Journal ArticleDOI
TL;DR: B-type natriuretic peptide blood concentration measurement appears to be a sensitive and specific test to diagnose CHF in urgent-care settings.

796 citations


Journal ArticleDOI
TL;DR: In a large cohort of patients with advanced HF of multiple etiologies, obesity is not associated with increased mortality and may confer a more favorable prognosis, and weight loss promotion in medically optimized patients with HF is a worthwhile therapeutic goal.

775 citations


Journal ArticleDOI
TL;DR: The origin, clinical relevance and treatment of pulse pressure is reviewed, and a distributed compliance model of the arterial circulation provides a framework for understanding the causes, effects and potential treatment of elevations in PP.

Journal ArticleDOI
TL;DR: An understanding of the epidemiology and natural history of AF is crucial to the future allocation of resources and the utilization of an expanding range of therapies aimed at reducing the impact of this disease on a changing patient population.

Journal ArticleDOI
TL;DR: In this article, the authors evaluated the accuracy in determining coronary lesion configuration by multislice computed tomography (MSCT) and compared with the findings of intracoronary ultrasound (ICUS).

Journal ArticleDOI
TL;DR: This document reflects the opinion of the third ACC/AHA committee charged with revising the guidelines for PTCA to include the broader group of technologies now termed PCI, and is to be viewed as broad recommendations to aid in the appropriate application of PCI.

Journal ArticleDOI
TL;DR: Lower GFR and hematocrit were associated with a higher prevalence of traditional cardiovascular risk factors and decreased kidney function and anemia are risk factors for all-cause mortality in patients with LV dysfunction.

Journal ArticleDOI
TL;DR: In patients admitted with decompensated CHF, changes in BNP levels during treatment are strong predictors for mortality and early readmission, and the results suggest that B NP levels might be used successfully to guide treatment of patients admitted for decompensation CHF.

Journal ArticleDOI
TL;DR: When anemia in CHF is treated with EPO and IV iron, a marked improvement in cardiac and patient function is seen, associated with less hospitalization and renal impairment and less need for diuretics.


Journal ArticleDOI
TL;DR: A successfully revascularized CTO confers a significant 10-year survival advantage compared with failed revascularization and success rates have continued to improve without an accompanying increase in MACE rates.

Journal ArticleDOI
TL;DR: Echocardiographic findings suggestive of subclinical contractile dysfunction and diastolic filling abnormalities are both predictive of subsequent CHF.

Journal ArticleDOI
TL;DR: There was a strong and graded association between the severity of depressive symptoms at baseline and the rate of the combined end point of either functional decline or death at six months.

Journal ArticleDOI
TL;DR: Left ventricular relaxation, minimal pressure and preload determine Ea while late diastolic velocity determinants include LA dP/dt, LA relaxation and LV end-diastolic pressure.

Journal ArticleDOI
TL;DR: The E(es) can be reliably estimated from simple noninvasive measurements and should broaden the clinical applicability of this useful parameter for assessing systolic function, therapeutic response and ventricular-arterial interaction.

Journal ArticleDOI
TL;DR: Bone marrow cells secrete angiogenic factors that induce endothelial cell proliferation and, when injected transendocardially, augment collateral perfusion and myocardial function in ischemic myocardium.

Journal ArticleDOI
TL;DR: Metformin treatment improved both insulin resistance and endothelial function, with a strong statistical link between these variables, and supports the concept of the central role of insulin resistance in the pathogenesis of endothelial dysfunction in type 2 diabetes mellitus.

Journal ArticleDOI
TL;DR: If endothelial dysfunction is an integral component of the pathogenesis of vascular disease, as currently believed, this study supports the value of an exercise program in the management of type 2 diabetes.

Journal ArticleDOI
TL;DR: Heart rate at 1 or 2 min of recovery has been validated as a prognostic measurement and should be recorded as part of all treadmill tests and should not replace, but is supplemental to, established scores.

Journal ArticleDOI
TL;DR: Nuclear factor kappa-B may be a new therapeutic target for myocardial protection and a possible role of NFkappaB in the development of atherosclerosis and unstable coronary syndromes is discussed.

Journal ArticleDOI
TL;DR: In this article, the electron beam computed tomographic (EBCT) calcium scores with the results of coronary angiography in symptomatic patients in order to assess its value to predict or exclude significant coronary artery disease (CAD).

Journal ArticleDOI
TL;DR: Measurement of plasma BNP concentrations might provide a useful and cost-effective screening tool that helps reduce the need and frequency for more expensive cardiac tests.