Showing papers in "Journal of the American College of Cardiology in 2003"

TL;DR: This work suggests that studies of endothelial function could be used in the care of patients and as a surrogate marker for the evaluation of new therapeutic strategies, and a growing number of interventions known to reduce cardiovascular risk have been shown to improve endothelialfunction.

TL;DR: There are extensive revisions, especially of the sections on ischemic heart disease; congestive heart failure, cardiomyopathy, and assessment of left ventricular (LV) function; and screening and echocardiography in the critically ill.

TL;DR: The American College of Cardiology/AHA Task Force on Practice Guidelines regularly reviews existing guidelines to determine when an update or full revision is needed.

TL;DR: In this paper, the authors present a general approach for the natural history and clinical course of clinical diagnostics in the context of vascular flow outflow and genetic and molecular diagnostics.

TL;DR: Sports activity in adolescents and young adults was associated with an increased risk of SD, both in males and females, and was strongly related to underlying cardiovascular diseases such as congenital coronary artery anomaly, arrhythmogenic right ventricular cardiomyopathy, and premature coronary artery disease.

TL;DR: These preliminary data suggest the feasibility and safety of autologous skeletal myoblast transplantation in severe ischemic cardiomyopathy, with the caveat of an arrhythmogenic potential, and new-onset contraction of akinetic and nonviable segments suggests a functional efficacy that requires confirmation by randomized studies.

TL;DR: This study demonstrates the natural history of aspirin resistance in a stable population, documenting a greater than threefold increase in the risk of major adverse events associated with aspirin resistance.

TL;DR: In this paper, the authors compared two treatment strategies in patients with atrial fibrillation (AF): rhythm control (restoration and maintenance of sinus rhythm) and rate control (pharmacologic or invasive rate-control and anticoagulation).

TL;DR: The level of GFR is an independent risk factor for ASCVD and de novo ASCVD in the ARIC study, and a nonlinear model did not fit the data better than a linear model.

TL;DR: This document was approved by the American College of Cardiology Foundation Board of Trustees in May 2003, byThe American Heart Association Science Advisory and Coordinating Committee in May2003, and by theAmerican Society of Echocardiography Board of Directors in May 2002.

TL;DR: Pulmonary vein ablation improves mortality, morbidity, and QoL as compared with medical therapy, paving the way for randomized trials to prospect a wider application of ablation therapy for AF.

TL;DR: Cardiologists and other providers routinely caring for older patients with CHF may improve outcomes in this high-risk population by better recognizing non-CHF conditions, which may complicate traditional CHF management strategies.

TL;DR: Gadolinium CMR reveals myocardial hyperenhancement in HCM and is associated with progressive ventricular dilation and markers of sudden death.

TL;DR: Impaired brachial-artery endothelial function independently predicts long-term cardiovascular events in patients with peripheral arterial disease, and noninvasive assessment of endothelium-dependent flow-mediated dilation (FMD) may serve as a surrogate end point for cardiovascular risk.

TL;DR: The CRT improved functional status in patients indicated for an ICD who also have symptomatic HF and intraventricular conduction delay and a subgroup of patients with advanced HF consistently demonstrated improvement across all functional status end points.

TL;DR: Findings suggested that neither abnormalities in the coronary circulation nor acute myocarditis was related to the etiology of transient left ventricular (LV) apical ballooning.

TL;DR: Polymerase chain reaction identified adenovirus as the most common virus in the myocardium of children and adults with myocarditis and DCM, and enteroviruses are also found in these patients.

TL;DR: These data suggest that beneficial effects may occur during early phases of treatment with beraprost in WHO functional class II or III patients but that this effect attenuates with time.

TL;DR: In this paper, the authors present a set of guidelines for the diagnosis and management of supraventricular arrhythmias, which are intended to assist physicians in clinical decision-making by describing a range of generally acceptable approaches.

TL;DR: Survival analysis showed that clinical profiles predict outcomes in HF and may be used to guide therapy and identify populations for future investigation.

TL;DR: Mortality and quality of life in patients with NIDCM and NSVT treated with amiodarone or an ICD are not statistically different and there is a trend towards a more beneficial cost profile and improved arrhythmia-free survival with amioarone therapy.

TL;DR: This pilot study is the first to demonstrate the potential and feasibility of percutaneous skeletal myoblast delivery as a stand-alone procedure for myocardial repair in patients with post-infarction HF.

TL;DR: Exercise training significantly reduced the local expression of TNF-alpha, IL-1-beta,IL-6, and iNOS in the skeletal muscle of CHF patients, suggesting that the local anti-inflammatory effects of exercise may attenuate the catabolic wasting process associated with the progression ofCHF.

TL;DR: The increase in NADPH oxidase activity in the failing heart may be important in the pathophysiology of cardiac dysfunction by contributing to increased oxidative stress.

TL;DR: Whether the ratio of peak tricuspid regurgitant velocity to the right ventricular outflow tract time-velocity integral obtained by Doppler echocardiography (TRV/TVI(RVOT)) provides a clinically reliable method to determine pulmonary vascular resistance (PVR) is tested.

TL;DR: A simple technique of measuring LAV is described, methods for indexing LAV are examined, and its normal range in a large, healthy reference cohort is described.

TL;DR: The low vitamin D status can explain alterations in mineral metabolism as well as myocardial dysfunction in the CHF patients, and it may therefore be a contributing factor in the pathogenesis of CHF.

TL;DR: Reducing the lipid component and inflammation in atherosclerotic plaques may help reduce the risk of plaque rupture, and may account for the clinical benefit of risk-factor reduction gained from changes in lifestyle and from drug therapy.

TL;DR: E/e' is a powerful predictor of survival after acute MI and an E/e’ ratio >15 is superior, in this respect, to other clinical or echocardiographic features.

TL;DR: Functional mitral regurgitation is reduced by CRT in patients with HF and LBBB and the hypothesis that an increase in TMP, mediated by a rise in LV+dP/dt(max) due to more coordinated LV contraction, may facilitate effective mitral valve closure is supported.