Showing papers in "Journal of the American College of Cardiology in 2007"

TL;DR: The best available evidence suggests that people with MetSyn are at increased risk of cardiovascular events and should fuel research of other preventive interventions.

TL;DR: Five-year outcome after deferral of PCI of an intermediate coronary stenosis based on FFR >/=0.75 is excellent and the risk of cardiac death or myocardial infarction related to this stenosis is <1% per year and not decreased by stenting.

TL;DR: The 2007 Guidelines on Perioperative Cardiovascular Evaluation for Non-Cardiac Surgery (e159-e242) as discussed by the authors were developed by the American College of ACC/AHA Task Force on Practice Guidelines Care for Noncardiac Surgery.

TL;DR: WRITING COMMITTEE MEMBERS Lee A. Fleisher, MD, FACC, FAHA, Chair; Joshua A. Beckman,MD, F ACC¶; Kenneth A. Kasper, MD; Judy R. Kersten,MD; Barbara Riegel, DNSc, RN,FAHA.

TL;DR: The molecular, cellular, and vascular processes supporting the role of low ESS in the natural history of coronary atherosclerosis and vascular remodeling are explored and likely mechanisms concerning the different natural history trajectories of individual coronary lesions are indicated.

TL;DR: The CAC Measurement Method helps clarify the role of risk assessment in Cardiovascular Medicine and current approaches to Global Risk Assessment and to match the intensity of intervention with the severity of risk.

TL;DR: This large observational data series shows that CAC provides independent incremental information in addition to traditional risk factors in the prediction of all-cause mortality.

TL;DR: Aortic stiffening is the principal cause of cardiovascular disease with age in persons who escape atherosclerotic complications, and the principal target is the smooth muscle in distributing arteries, whose relaxation has little effect on peripheral resistance but causes substantial reduction in the magnitude of wave reflection.

TL;DR: Treatment of severe aortic valve stenosis in high-risk patients with percutaneous implantation of the CoreValve prosthesis is feasible and associated with a lower mortality rate than predicted by risk algorithms.

TL;DR: It seems desirable to maintain resting HR substantially below the traditionally defined tachycardia threshold of 90 or 100 beats/min, which may be difficult to define an optimal HR for a given individual.

TL;DR: Obesity and the magnitude of nocturnal oxygen desaturation, which is an important pathophysiological consequence of OSA, are independent risk factors for incident AF in individuals <65 years of age.

TL;DR: In decompensated HF, ultrafiltration safely produces greater weight and fluid loss than intravenous diuretics, reduces 90-day resource utilization for HF, and is an effective alternative therapy.

TL;DR: The CT characteristics of plaques associated with ACS include positive vascular remodeling, low plaque density, and spotty calcification, and it is logical to presume that plaques vulnerable to rupture harbor similar characteristics.

TL;DR: In this article, the impact of individual response variability to clopidogrel on clinical outcomes and current and future directions for its management is reviewed. But, despite the use of clopidine, a considerable number of patients continue to have cardiovascular events.

TL;DR: In patients with chest pain, CCTA identifies increased risk for all-cause death and a negative C CTA portends an extremely low risk for death.

TL;DR: Data from the OPTIMIZE-HF registry reveal a high prevalence of HF with PSF, and these patients have a similar post-discharge mortality risk and equally high rates of rehospitalization as patients with HF and LVSD.

TL;DR: Red cell distribution width was found to be a very strong independent predictor of morbidity and mortality in 2 large contemporary heart failure populations and may provide novel insights into heart failure pathophysiology.

TL;DR: The burden of CVD on women and the global economy will continue to increase as life expectancy continues to increase and economies become more industrialized.

TL;DR: Optical coherence tomography is a feasible imaging modality in patients with AMI and allows us to identify not only plaque rupture, but also fibrous cap erosion, intracoronary thrombus, and TCFA in vivo more frequently compared with conventional imaging techniques.

TL;DR: In this article, a logistic regression was used to determine predictors of 30-day major bleeding and mortality in patients with acute coronary syndromes (ACS) undergoing an early invasive strategy and showed that major bleeding rates in patients treated with heparin plus glycoprotein IIb/IIIa inhibition were higher versus bivalirudin monotherapy.

TL;DR: In this analysis of the CHARISMA trial, the large number of patients with documented prior MI, ischemic stroke, or symptomatic PAD appeared to derive significant benefit from dual antiplatelet therapy with clopidogrel plus aspirin.

TL;DR: Nonresponsiveness to clopidogrel is a strong independent predictor of stent thrombosis in patients receiving sirolimus- or paclitaxel-eluting stents.

TL;DR: Cure of CDI is achievable in the large majority of patients treated with an aggressive approach of combined antimicrobial treatment and complete device removal, and proposed management guidelines ofCDI are submitted.

TL;DR: In optimally treated CHF patients, a BNP-guided strategy reduced the risk of CHF-related death or hospital stay for CHF, mainly through an increase in ACEI and beta-blocker dosages.

TL;DR: This statement examines the relation of the resting ECG to its technology to establish standards that will improve the accuracy and usefulness of the ECG in practice and to recommend recommendations for ECG standards.

TL;DR: Multi-slice computed tomographic coronary angiography can definitively establish or exclude coronary disease as the cause of chest pain and inability to determine the physiological significance of intermediate severity coronary lesions and cases with inadequate image quality are present limitations.

TL;DR: 6 areas of controversy regarding hsCRP are resolvable with a consensus position that focuses in primary prevention on selective use among individuals with 5% to 20% 10-year risk as estimated by Adult Treatment Panel III, and focuses in secondary prevention on high-risk patients being treated with statin therapy.

TL;DR: This statement examines the relation of the resting ECG to its technology to establish standards that will improve the accuracy and usefulness of the ECG in practice and to recommend recommendations for ECG standards.

TL;DR: The mortality rates for CHD among younger adults may serve as a sentinel event and unfavorable trends in several risk factors forCHD provide a likely explanation for the observed mortality rates.