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Showing papers in "Journal of Trace Elements in Medicine and Biology in 2006"


Journal ArticleDOI
TL;DR: A multidisciplinary approach will most likely result in success in the pharmacology of zinc compounds as a promising area for translational research, and the current assumed range between safe and unsafe intakes of zinc is relatively narrow.

920 citations


Journal ArticleDOI
TL;DR: The trace elements Ag, As, Au, B, Ba, Be, Bi, Cd, Ce, Co, Cs, Cu, Ga, Hf, Hg, In, La, Mn, Mo, Ni, Pb, Pd, Rb, Rh, Ru, Sb, Se, Sn, Sr, Te, Th, Tl, U, V, W, Y and Zr were determined in 130 human blood samples from occupationally non-exp

236 citations


Journal ArticleDOI
TL;DR: Structural and functional changes induced in pollen grains and stigma of Zn deficient plants and associated decrease in seed setting of lentil indicate a critical requirement of ZN for pollen function and fertilisation that can be partially met by supplementing Zn at the onset of the reproductive phase.

155 citations


Journal ArticleDOI
TL;DR: The results suggest that the high Cd sensitivity of Hamidiye is related to enhanced production and oxidative damage of ROS, and in response to increasing Cd supply particular increases in antioxidative mechanisms in the Cd-sensitive barley cultivar hamidiye are suggested.

154 citations


Journal ArticleDOI
TL;DR: It was concluded that the inhibitory effect of phytate on the absorption of zinc and the retention of calcium was dose dependent.

136 citations


Journal ArticleDOI
TL;DR: In the fermented mushroom of C. comatus, vanadium at lower doses in combination with C.Comatus rich in vanadium, induced significant decreases of the blood glucose and HbA1c levels in hyperglycemic mice.

66 citations


Journal ArticleDOI
TL;DR: Concomitant administration of zinc with arsenic showed remarkable protection against blood delta-aminolevulinic acid dehydratase (ALAD) activity as well as providing protection to hepatic biochemical variables indicative of oxidative stress and tissue injury.

63 citations


Journal ArticleDOI
TL;DR: The results show that the effect of aging on the intestinal mineral absorption and status differ largely according to the mineral considered, and further studies are required under different nutritional conditions to explore the underlying mechanisms during aging and to adjust a better nutrition of the elderly.

59 citations


Journal ArticleDOI
Xiuan Zhan1, Min Wang1, Zirong Xu1, Wei Fen Li1, Jian Xin Li1 
TL;DR: F fluoride causes a decrease in Cu/Zn SOD mRNA and the reduced activities of antioxidant enzymes, leads to the declined ability of scavenging free radicals with excessive production of LPO, which seriously damages the hepatic structure and function.

53 citations


Journal ArticleDOI
TL;DR: Measures of trace metals status appear to be associated with the risk of atherosclerosis in a Saudi male population.

50 citations


Journal ArticleDOI
TL;DR: Melatonin co-treatment brought about a dose-dependent decrease in the renal, hepatic and intestinal Cd concentrations, and the renal and hepatic metallothionein levels followed a pattern similar to that of the Cd accumulation.

Journal ArticleDOI
TL;DR: The present investigation suggests that T. chebula extract could be used as therapeutic agent for cancer prevention as evident from this study where it blocks or suppresses the events associated with chemical carcinogenesis.

Journal ArticleDOI
TL;DR: Metal levels in patients who had undergone metal-on-metal hybrid surface arthroplasties on the supposition that a release of metals would occur due to the large head size of this type of implant showed a significant difference between patients and control subjects in mean levels of Co and Cr in serum and urine.

Journal ArticleDOI
TL;DR: The results suggest the existence of a chemical-hormesis phenomenon that might be subjected to sexual-genre variability and the possible causes for this double inhibition are briefly discussed.

Journal ArticleDOI
TL;DR: The maximum leachate concentrations of Cd, Ni, Pb, Cu and Zn were all below drinking water quality guidance limits set by Florida Department of Environmental Protection and World Health Organization, suggesting that the application of DPR fertilizers may not pose a threat to water quality by leaching.

Journal ArticleDOI
TL;DR: Lead levels within follicular fluid were found to be significantly higher in non-pregnant patients compared to pregnant patients suggesting that elevated concentrations of the environmental toxicant lead adversely affect female reproduction.

Journal ArticleDOI
TL;DR: Interestingly, the combined effect of SMF and Cd decreased the GPx and CAT activities in liver compared to cadmium treated group, however, the association between SMFs failed to alter transaminases, MDA and 8-oxodGuo concentration.

Journal ArticleDOI
TL;DR: The low cellular Al uptake as well as some inherent insensitivity related to the cell type might be contributory factors for the small effect of Al on kidney cells and markers of oxidative damage.

Journal ArticleDOI
TL;DR: The results reveal an extensive interspecies variation in yolk Se (across a 6-fold range) for eggs collected from the wild and the effect of phylogenetic relatedness among these species is so significant that it removes any effect of geographical location.

Journal ArticleDOI
TL;DR: Content of Cd and Pb in kidneys of fetuses and newborns was extremely low, however, it was significantly increased in adjacent-normal tissues of kidneys with carcinomas, and significantly higher compared to kidneys of individuals that died of non-neoplastic diseases.

Journal ArticleDOI
TL;DR: CRC454 showed significant reduction of hyperglycemia under insulin-deficient conditions and improvement of body weight gains and blood levels of CK, AST and ALT seems to be less dependent on the type of chromium compound under these experimental conditions.

Journal ArticleDOI
TL;DR: When mineral uptakes from raw, traditionally cooked, and ready- to-eat lentils were compared, the highest uptake values corresponded to the ready-to-eat product, which could be attributed to the combined effect of EDTA soaking, the cooking under pressure process, and citric and ascorbic acid addition.

Journal ArticleDOI
TL;DR: The results indicate that more than 90% of Mo contained in a routine dietary menu is absorbed, most of Mo absorbed is excreted in urine, and Mo balance is in equilibrium in the general Japanese population.

Journal ArticleDOI
TL;DR: It could be shown that in most cases bioactive trace elements like Fe can be found in rock salt in the form of almost insoluble compounds and are therefore not significantly bioavailable, whereas thorium, for example, was partly bioavailable in two cases.

Journal ArticleDOI
TL;DR: A numerical model for water flow and trace element transport has been developed based on analyzing the characteristics of migration and transformation of trace elements leached from coal mine spoil and provides theoretical evidence for quantitative assessment soil-water quality of trace element Transport on environment pollution.


Journal ArticleDOI
TL;DR: The urinary levels of seven trace elements were determined by atomic spectrometric methods (ICP-MS and GFAAS) in 100 urine samples of the Viennese population to establish reference concentrations of metals.

Journal ArticleDOI
TL;DR: The serum molybdenum concentrations in 70 Japanese adults not receiving any medical care or treatment were determined by inductively coupled plasma-mass spectrometry, and activities of aspartate aminotransferase and alanine aminotsferase showed significant associations with serum Mo.

Journal ArticleDOI
TL;DR: The study results indicate an improvement of iron status indicators in mice when they were fed sourdough bread as compared to baking yeast bread and bread with no starters.

Journal ArticleDOI
TL;DR: In Inuit, liver Rb content appears to decrease with age, which is quite similar to the levels found in Danes.