Showing papers in "Materials Science and Engineering: C in 2017"

TL;DR: It is highlighted that, despite its encouraging results, the clinical approach of Bone Tissue Engineering has not taken place on a large scale yet, due to the need of more in depth studies, its high manufacturing costs and the difficulty to obtain regulatory approval.

TL;DR: This article focuses on biocompatible metals which favorably used as implants such as 316L stainless steel, cobalt-chromium-molybdenum, pure titanium and titanium-based alloys, and the mechanism to improve it.

TL;DR: In this review, several strategies including interpenetrating polymer network (IPN), double network (DN), nanocomposite (NC) and slide ring (SR) hydrogels are discussed in the context of PNIPAM hydrogel.

TL;DR: This paper presents a state-of-the-art overview mainly on manufacturing, topological design, mechanical properties and biocompatibility of cellular Ti-6Al-4V scaffolds via SLM and SEBM methods.

TL;DR: This review focuses on the toolbox of available methods for the preparation of polymeric nanoparticles and highlights some recent examples from the literature that demonstrate the influence of the preparation method on the physicochemical characteristics of the nanoparticles.

TL;DR: An overview of some recent advances of electrospinning-based nanomaterials in biomedical applications such as antibacterial mats, patches for rapid hemostasis, wound dressings, drug delivery systems, as well as tissue engineering are given.

TL;DR: The present review discusses the subject on the miscellaneous hydrogel with regard to their raw materials, methods of fabrication and applications, and summarizes the classification of hydrogels, based on their cross-linking and physical states.

TL;DR: In vitro drug release results showed that the loaded TH could be sustained release from the composite gel dressing by contrast with pure hydrogels and microspheres, and powerful bacteria growth inhibition effects against Escherichia coli and Staphylococcus aureus suggested that the composite dressing has a promising future in treatment of bacterial infection.

TL;DR: The design of electrospun polymer/protein nanofiber membranes was effective for guided bone regeneration and the in vitro osteogenesis characterizations, alizarin red in normal medium and osteogenesis medium, indicated that the nanofibers could promote bone formation.

TL;DR: The cytotoxicity results showed that the CDs exhibit non toxicity within 100μg/mL, indicating that they are promising fluorescent probes for biological imaging and successfully applied for Fe3+ probing in living cells.

TL;DR: The synthesis of high quality ZnO doped TiO2 nanocrystals by chemical method at room temperature (RT), which exhibits antibacterial activity over a broad range of bacterial species and in particular against Stre.

TL;DR: This review paper focuses on LCC strategies including co-delivery of: two chemotherapeutic drugs, chemtherapeutic agent with anti-cancer metals, and chemotherapedic agent with gene agents and ligand-targeted liposome for co-Delivery of chemotherAPEutic agents.

TL;DR: In this review, colorimetric sensors for the detection of biomolecules like protein, DNA, pathogen and chemical compounds like heavy metal ions, toxic gases and organic compounds have been elaborately discussed.

TL;DR: In vitro indirect MTT assay showed that the developed drug-loaded nanofibrous scaffolds have good cytocompatibility, indicating that the investigated scaffold may be used as antibacterial wound dressing for healing promotion.

TL;DR: General recommendations for future pre-clinical studies that allow better standardization of study protocols will allow better comparison and contrast of newly developed bone substitute biomaterials that help further progress in the field of biomaterial science.

TL;DR: Preliminary advantages of the TiZrNbTaMo HEA over the current orthopedic implant metals in mechanical properties and corrosion resistance offer an opportunity to explore new orthopedics-implant alloys based on the Ti ZrN bTaMo concentrated composition.

TL;DR: Efforts are being made to devise a scaffold that is biodegradable, biocompatible, conducting and immunologically inert, and to elicit a combination of biochemical, topographical and electrical cues via various polymers, cells and growth factors, using which nerve regeneration can efficiently occur.

TL;DR: The present review covers research conducted on the fabrication techniques, surface modifications, properties and biological characteristics of Mg alloys based scaffolds and the potential applications, challenges, and future trends are discussed in detail.

TL;DR: This paper provides a guiding strategy for the selection of optimal approaches to the fabrication of nanocarriers that are suitable for medical treatments and to controlling the toxicity within therapeutic safety limits.

TL;DR: In this review, a range of in vitro and in vivo studies have been critically discussed to explore the pharmaceutical significance and therapeutic viability of the advanced delivery systems to improve antioxidant, anti-inflammatory and antimicrobial efficacies of curcumin and its derivatives.

TL;DR: Three ZnAg alloys with Ag content ranging from 2.5 to 7.0wt% are designed and displayed superplasticity over a wide range of strain rates providing the possibility of exploiting forming processes at rapid rates and/or even at lower temperatures.

TL;DR: In this review, the most recent developments of PHB-based toughening materials are discussed with respect to their approaches and strategies, which includes: drawing and thermal treatment, blending with materials from natural sources and synthetic polymers, as well as forming reinforced composites with natural fibers and inorganic fillers.

TL;DR: An overview of the progress made on the graphene oxide nanocomposites as a new generation of antimicrobial agents is given.

TL;DR: The trimetallic and bimetallic nanoparticles are of enormous attention in both technological and scientific view as in these nanoparticles the catalytic properties can be tailored better than that of in the single monometallic catalyst.

TL;DR: The prepared CMC nanocomposite hydrogel containing ZnO impregnated MCM-41, could serve as a kind of promising wound dressing with sustained drug delivery properties with improved tensile strength, swelling, erosion, and gas permeability properties.

TL;DR: Various nano-delivery systems consisting of different covalent linkages to conjugate the therapeutic molecules as well as those that carry the unmodified drug molecules by encapsulating or complexation are summarized, including ester, amide/peptide, disulfide, hydrazone, hypoxia-activated and self-immolative linkages.

TL;DR: The synthesis of PGS-based copolymers with methyl methacrylate might be a promising approach to enhance their processability, and therefore advancing bioscaffold engineering for various TE applications.

TL;DR: The in vitro release of beads exhibited significant behavior on the subject of nanoparticles concentration and alginate content and biocompatibility of the CFO nanoparticles and MCFO/Alg beads are demonstrated through cytotoxicity test via MTT assay on U87 cell lines.

TL;DR: Carboxymethyl chitosans show improved solubility in aqueous media, which makes them an attractive alternative source for producing biomaterials and drug delivery systems as well as for designing nanotechnology based systems.

TL;DR: This article critically reviews the use of the response surface methodologies in pharmaceutical and food microencapsulation research areas and survey of optimization procedures in the literature, in the last few years is presented.