Journal•ISSN: 1567-7249
Mitochondrion
Elsevier BV
About: Mitochondrion is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Mitochondrion & Mitochondrial DNA. It has an ISSN identifier of 1567-7249. Over the lifetime, 1896 publications have been published receiving 62572 citations. The journal is also known as: mitochondria & GO:0005739.
Topics: Mitochondrion, Mitochondrial DNA, Mitochondrial disease, Gene, Medicine
Papers published on a yearly basis
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TL;DR: There is accumulating evidence that mitochondrial dysfunction (more particularly respiratory chain deficiency) plays a key role in the physiopathology of NASH whatever its initial cause and that several drugs can prevent or even reverse NASH.
661 citations
TL;DR: The notion of functional compartmentalization of mitochondria is presented as a means by which ATP may be differentially supplied and localized within the cytoplasm by virtue of stage-specific changes in mitochondrial density and potential.
471 citations
TL;DR: The clinical phenotypes of bioenergetic diseases are strikingly similar to those observed in epigenetic diseases (Angelman, Rett, Fragile X Syndromes, the laminopathies, cancer, etc.), and an increasing number of epigenetics diseases are being associated with mitochondrial dysfunction.
461 citations
TL;DR: CoQ biosynthesis is influenced by nuclear receptors which may give the possibility, in the future, by using agonists or antagonists, of reestablishing the normal level in deficiencies caused by genetic mutations, aging or cardiomyopathy.
454 citations
TL;DR: It is suggested that more ROS are generated from mitochondria in ETC-inhibited and mtDNA-damaged cells, which have impaired ETC.
440 citations