Showing papers in "Natural Product Research in 2006"

TL;DR: Anti-inflammatory sesquiterpene furanodiene and furanodienone suppressed the TPA-induced inflammation of mouse ears by 75% and 53%, respectively, at a dose of 1.0 µmol and their activities are comparable to that of indomethacin, the normally used anti-inflammatory agent.

TL;DR: Ethyl acetate extract of sumac may have interest in the treatment and prevention of hyperglycaemia, diabetes and obesity, with an IC50 value of 28.7 µg mL−1.

TL;DR: Interestingly, the cytotoxicity induced by compound 1 against Hep cell line is more important than that induced by adriamycin used as a positive control.

TL;DR: All the crude extracts when screened for their larvicidal activities indicated very good toxicity against the larvae of Aedes aegypti.

TL;DR: The Millefolii herba grown in Estonia conforms to the European Pharmacopoeia (EP) standards in the aspect of the essential oil contents and contains high amounts of monoterpenes and chamazulene.

TL;DR: The essential oil extracted by supercritical CO2 extraction and hydrodistillation exhibited antifungal activity against Botrytis cinerea and Alternaria alternate, two common storage pathogens of fruits and vegetables.

TL;DR: Both enantiomers of usnic acid are non-genotoxic shown by the absence of micronucleus induction in human lymphocytes and have significant cytotoxic and apoptotic effects to induce cell killing in culturedhuman lymphocytes, V79 and A549 cell lines.

TL;DR: The antimicrobial potentiality of the methanolic extract of Phyllanthus amarus was studied against some drug resistant pathogenic bacterial strains by disc diffusion and agar dilution method and showed significant concentration-dependent antibacterial activity particularly against gram-negative microbes.

TL;DR: Sixteen extracts, obtained from eight Brazilian plants of Annonaceae family, were screened for their antibacterial activity and a phytochemical screening showed the presence of anonaceus acetogenins in some active extracts.

TL;DR: The efficacy of the plant as a strong biocontrol agent of the larval anopheline mosquito was evaluated in the laboratory and bioactive ingredients were characterized by thin layer chromatography (TLC) and infrared (IR) analysis.

TL;DR: Three new acylated quercetin rhamnosides have been isolated from the leaves and stem of Calliandra haematocephala Hassk and exhibited lethal effect towards brine shrimp Artemia salina.

TL;DR: Two new lanostanoids were isolated from a lipophilic extract of the fruiting body of Ganoderma lucidum and both exhibited inhibitory activities against the HMG-CoA reductase and acyl CoA acyltransferase.

TL;DR: An ethanolic extract of the leaves of Annona muricata was shown to be toxic to adult forms of the snail Biomphalaria glabrata and to larvae of the brine shrimp Artemia salina.

TL;DR: Two biflavonoids, ginkgetin and sciadopitysin, were isolated from the MeOH extract of the young branches of Taxus cuspidata, which inhibited phosphatase of regenerating liver-3 (PRL-3) with IC50 values of 25.8 and 46.2 μM, respectively.

TL;DR: Conclusively, exclusive honey feeding (50% concentration) significantly modifies and ameliorates biochemical and hematological changes obtained after CCl4 injection.

TL;DR: The chemical composition of the essential oil from the aerial parts of Chromolaena odorata, collected from Phitsanulok, Thailand was analyzed by means of GC-(FID) and GC-MS as discussed by the authors.

TL;DR: A phytochemical study of the petroleum ether and ethyl acetate extracts of the entire plant of Arbutus unedo led to the isolation of a new sterol, 7β-hydroxystigmast-4-en-3-one, and nine known compounds of the flavan, steroid, and terpenoid types.

TL;DR: Three compounds are isolated and screened and only polycarpol and 3-O-acetyl aleuritolic acid exhibited significant inhibitory activities on the vitality of adult male worms of O. gutturosa using Amocarzine as positive control compound.

TL;DR: The reversed-phase preparative HPLC analysis of the methanol extract of the rhizomes of Eremostachys glabra (Lamiaceae) led to the isolation of two furanolabdane diterpene glycosides, phlomisoside II, and β-D-glucopyranosyl-(1→2)-β-D

TL;DR: Tithoniamarin (1), a new isocoumarin dimer and a new ceramide, named tith oniamide (2a), have been isolated from Tithonia diversifolia and the structures were elucidated on the basis of spectroscopic and chemical evidence.

TL;DR: Phytochemical investigation of the gum resin of Ferula assafoetida resulted in the isolation and characterization of a new sesquiterpenoid coumarin, Saradaferin named as Decahydro-(3-α-hydroxy-4,4,10-trimethyl-8-methylene-9-naphthenyl)-α-Hydroxymethyl ether of umbelliferone.

TL;DR: The anticancer activity of the three isolated compounds and of a synthetic sample of osthol was evaluated on L1210 mouse leukemia and on human prostatic cancer hormonosensitive LNCaP and hormonoindependent PC3 and DU145 cell lines.

TL;DR: In this article, the brine shrimp lethality test (BSLT) was used to direct the fractionation and isolation of active components of Jordanian Colchicum species, and five and four known colchicinoids were isolated and characterized from C. tunicatum and C. hierosolymitanum.

TL;DR: Fractionation of the aerial parts of Chromolaena odorata afforded a new flavonoids, 5,7-dihydroxy-6,4′-dimethoxyflavanone, in addition to 14 known flavonoid compounds, six of which had not been isolated previously from this plant.

TL;DR: This study purified bactericidal antibiotic from the ethyl acetate extract of the cells of P. aeruginosa and analyzed its chemical structure, which is proposed to be 1-methyl-1,4 dihydroquinoline and is active against methicillin-resistant Staphylococcus aureus (MRSA) and other pathogens.

TL;DR: Due to their antifungal and antioxidant properties, the essential oil and the methanolic extract of T. sauvagei may be of use as natural preservative ingredients in food and/or pharmaceutical industries.

TL;DR: This plant is a new source of linalyl acetate, a valuable perfumery compound, and nine and six volatile constituents respectively were identified by GCMS.

TL;DR: It is proposed that these glycoglycerolipids can be used as markers for monitoring the thermal mud colonisation process and show a marked presence of polyunsaturated fatty acids.

TL;DR: Bioguided fractionation of Cyrtocarpa procera Kunth extracts led to the isolation of β-sitosterol and the identification of 1,3-propyl-dipentadecanoate and 2,6,10-trimethyltetradecane by GC–MS.

TL;DR: The volatile constituents of Annona squamosa L. bark were identified from the essential oil obtained by steam distillation and studied by GC/MS, which exhibited a significant antimicrobial activity against Bacillus subtilis and Staphylococcus aureus.