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Showing papers in "Natural Product Research in 2007"


Journal ArticleDOI
TL;DR: Results show that flavonoids and saponins caused a significant reduction of walking time and coordinated movement ability of mouse, and significantly prolonged its sleeping time and increased the sleeping number of animals at 50 mg kg−1, ip, superthreshold dose induced by coeliac injection of sodium barbital.

192 citations


Journal ArticleDOI
TL;DR: There was a significant linear correlation between antioxidant activity and total phenolic content for aqueous and methanolic extracts, suggesting that phenolic compounds were the predominant antioxidant components in the investigated plant species.

136 citations


Journal ArticleDOI
TL;DR: Five flavonol glycosides characterised as kaempferide 3-O-(2″,3″-diacetylglucoside), Kaempferol 3- o-α-rhamnoside, ka Kempferol, syringic acid, gallic acid and rutin have been isolated from methanolic extract of Moringa oleifera leaves using spectroscopic methods and comparison with data from known compounds.

128 citations


Journal ArticleDOI
TL;DR: The comparatively high concentration of toxic thujones seem to be characteristic to sage leaves cultivated in Estonia, which varied in about the same range as the concentrations of these compounds in the oils of drugs obtained from other countries.

123 citations


Journal ArticleDOI
TL;DR: Two new flavonoids are isolated from Phyllanthus emblica on the basis of extensive spectroscopic studies including 2D-NMR experiments.

111 citations


Journal ArticleDOI
TL;DR: This study was to isolate antibacterial compounds from Gleditsia sinensis Lam through bioassay-guided fractionation (against a Gram-positive bacterium Xanthomonas vesicatoria and a gram-negative bacterium Bacillus subtilis) and showed moderate inhibitory activities against both bacterial species.

92 citations


Journal ArticleDOI
TL;DR: The results show that these oligosaccharides exhibited different activities in various assays, and COs had the highest scavenging superoxide radical and inhibiting erythrocyte hemolysis activity than AOs and FOs at all the tested amounts.

91 citations


Journal ArticleDOI
TL;DR: The results indicate that the mechanism of anti-inflammatory effect of glycyrrhizin most probably does not involve ROS and this major constituent is not responsible for the inhibition effects of liquorice extract on neutrophil functions.

80 citations


Journal ArticleDOI
TL;DR: Of the isolated compounds, syringic acid showed moderate antimalarial, anticandidal, and antimycobacterial activity; while mearnsetin and quercetin exhibited antioxidant activity comparable to ascorbic acid and trolox.

79 citations


Journal ArticleDOI
TL;DR: The isolation and structure elucidation of two previously undetected alkaloids, meridianins F and G, are reported herein.

79 citations


Journal ArticleDOI
TL;DR: In this article, the aerial parts of Cyperus rotundus L. afforded a new steroid glycoside named sitosteryl (6'-hentriacontanoyl)-beta-D-galactopyranoside (4) in addition to three furochromones, khellin (2), visnagin (3) and ammiol (9).

Journal ArticleDOI
TL;DR: Two new iridoids 6-O-[2,3-dimethoxy]-trans-cinnamoyl catalpol and 6- O-meta-methoxy-benzoylCatalpol are reported from Cissus quadrangularis Linn, the first reported occurrence of iridoid picroside 1 and the compounds 3 and 7 are first reported from this plant.

Journal ArticleDOI
Yin Lu1, Yunpeng Zhao1, Zhi can Wang1, Siqin Chen1, Cheng-Xin Fu1 
TL;DR: The results showed that Actinidia macrosperma exhibited a mild antibacterial activity against two Gram-positive bacteria, a significant activity against Gram-negative bacteria, and no activity on Pseudomonas aeruginosa.

Journal ArticleDOI
TL;DR: The honey proved more effective on bacteria than antibiotics, and samples which had highest antibacterial activity against P. aeruginosa, E. coli, and S. aureus.

Journal ArticleDOI
Xiao-Dong Yang1, Jie Zhu1, Rong Yang1, Jingping Liu1, Liang Li1, Hongbin Zhang1 
TL;DR: The HPLC chromatograms of different preparation processes were reported, and structures of nine phenolic compounds, isolated from Gastrodia elata, were assigned, and their structures were elucidated on the basis of spectral analyses, including 2D NMR spectroscopy.

Journal ArticleDOI
TL;DR: Aqueous, ethanol, and ethyl acetate extracts showed significant decrease in leucocytes and eosinophils in the order given while petroleum ether and chloroform extracts were inactive, showing the application of polar constituents of F. bengalensis bark as antistress and antiallergic agents in asthma.

Journal ArticleDOI
Sujun Liu1, Jie Zhang1, Daxu Li1, Wei Liu1, Xun Luo1, Rongxian Zhang1, Li Li1, Jian Zhao1 
TL;DR: Qualitative analysis of flavone by reversed-phase HPLC shows that these two flavones greatly inhibit cancer cell growth.

Journal ArticleDOI
TL;DR: The aryltetralin lignans 6-methoxypodophyllotoxin, 5′-demethoxy-6-mETHoxypicropodophyLLotoxin as well as the corresponding 8′-epimers 6-naphthalene lignan justicid in B and isojusticidin B were isolated from suspension cultures of Linum cariense.

Journal ArticleDOI
TL;DR: Three known sesquiterpene compounds, Isocostic acid, Carabrone and Tomentosin, together with two new compounds isolated from the acetone extract of Inula viscosa (L.) Aiton are studied.

Journal ArticleDOI
TL;DR: Production and optimisation of rosmarinic acid, a phenolic acid and an economically important metabolite, was investigated in the callus cultures established from the mature seeds of Satureja hortensis L. (summer savory) plant and an opposite relationship was determined between the growth and ros marinic acid production.

Journal ArticleDOI
TL;DR: The antioxidant activity of the crude extract and solvent fractions obtained from the leaves of Bauhinia galpinii was evaluated in terms of capacity to scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radicals and three flavonoid glycosides were reported for the first time from this species.

Journal ArticleDOI
TL;DR: Three anthraquinones, Cdc25B phosphatase inhibitors, were isolated from the methanolic extract of the roots of Polygonum multiflorum Thunb and strongly inhibited the growth of human colon cancer cells.

Journal ArticleDOI
TL;DR: Three phenolic compounds cosmosiin, caffeic acid, and p-coumaric acid were isolated for the first time from the leaves of Cupressus sempervirens L. together with cupressuflavone, amentoflavone, rutin, quercitrin, quERCetin, myricitrin and showed high antioxidant activity for quercetin.

Journal ArticleDOI
TL;DR: A new cytotoxic macrocyclic glycoresin, ipomoeassin F (6), has been isolated from the leaves of Ipomoea squamosa and the structure was elucidated by the interpretation of spectral data.

Journal ArticleDOI
TL;DR: Two ellagic acid glycosides were isolated by bioassay-guided fractionation from the antimicrobial ethyl acetate fraction of the ethanol extract from Gleditsia sinensis spines and showed significant antifungal activity against the spore germination of rice blast fungus Magnaporthe grisea.

Journal ArticleDOI
TL;DR: The reversed-phase HPLC analysis of a methanol extract of the aerial parts of Cuscuta reflexa afforded a non-separable mixture of two novel tetrahydrofuran derivatives, named swarnalin and cis-swarnalin, and a known coumarin, 5,6,7-trimethoxycoumarin.

Journal ArticleDOI
TL;DR: The investigated ethyl acetate extract was found to be non-toxic and had significant antioxidant, hepatoprotective, anti-inflammatory and antidiabetic activities and some of the isolated flavonoids showed cytotoxic activity against Ehrlich ascitis carcinoma cells.

Journal ArticleDOI
TL;DR: The chloroform, ethyl acetate, and butanol extracts of the plant were found to have mild to moderate inhibitory potentials against the enzyme tyrosinase.

Journal ArticleDOI
TL;DR: Mentha cervina oils with low content of pulegone, may be an alternative as antifungal agents in dermatophytosis, and evaluated by minimal inhibitory concentrations and minimal lethal concentrations against Candida, Apergillus and dermatophyte strains.

Journal ArticleDOI
TL;DR: The aldehyde is a modest inhibitor of the growth of Plasmodium falciparum and slow-proliferating breast cancer cells MCF7, but a potent inhibitor of proliferation of S180 cancer cells (IC50 7.4 µM), and the first report of humulenes found in the genus Trichilia and only the second of humULenes in the order Sapindales.