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Showing papers in "NeuroImage in 1995"


Journal ArticleDOI
TL;DR: The approach is predicated on an extension of the general linear model that allows for correlations between error terms due to physiological noise or correlations that ensue after temporal smoothing, and uses the effective degrees of freedom associated with the error term.

2,647 citations


Journal ArticleDOI
TL;DR: Correct results are presented that replace those of the previous paper and solve the same problem without recourse to heuristic arguments and a proper and unbiased estimator for the error terms are introduced.

2,154 citations



Journal ArticleDOI
TL;DR: Using this approach, the anterior cingulate differentiates, in terms of its response, between two motor tasks that did and did not require sustained attention, and it is suggested that these demonstration results point to the possibility of making greater use of the temporal resolution afforded by fast fMRI techniques.

677 citations


Journal ArticleDOI
TL;DR: Memory-related imagery was associated with significant activation of a medial parietal area, the precuneus, which provides strong evidence that it is a key part of the neural substate of visual imagery occurring in conscious memory recall.

653 citations


Journal ArticleDOI
TL;DR: A multivariate analysis of evoked hemodynamic responses and their spatiotemporal dynamics as measured with fast fMRI reveals some compelling and somewhat unexpected perspectives on transient but stereotyped responses to changes in cognitive or sensorimotor processing.

582 citations


Journal ArticleDOI
TL;DR: This method permits the detection of structural differences within the entire brain (as opposed to selected regions of interest) and may be of value in the investigation of structural gray and white matter abnormalities in a variety of brain diseases.

533 citations


Journal ArticleDOI
TL;DR: In this article, neuromagnetic data provided evidence for distinct functional roles of these spectral components in the somatomotor cortex and showed that the sites of suppression during movement and the subsequent rebound of the 20-Hz rhythm followed, along the motor cortex, the representation of fingers, toes, and mouth, as opposed to the stable origin of the 10-Hz rhythms close to the hand somatosensory cortex.

527 citations


Journal ArticleDOI
TL;DR: The energy metabolism of the adult human brain almost completely depends on glucose, which reflects neuronal activity and more specifically synaptic, mainly presynaptic, activity.

520 citations


Journal ArticleDOI
TL;DR: Increases in regional cerebral blood flow (rCBF) were observed in a network of structures that have been previously associated with selective attention, including the anterior cingulate gyrus, the frontal polar cortex, the inferior parietal lobule, and the thalamus, as well as the lingual gyrus.

473 citations


Journal ArticleDOI
TL;DR: To the authors' knowledge, this study is one of the first to demonstrate the applicability of fMRI to a normative developmental population and issues of age dependence of the hemodynamic responses of f MRI are discussed.

Journal ArticleDOI
TL;DR: The results of this study support a significant role for the cerebellum in cognitive functions such as memory and suggest that the human brain may contain a distributed multinodal general memory system.

Journal ArticleDOI
TL;DR: It is hoped that the systematic construction of the NeuroNames Brain Hierarchy will facilitate use of the most widely accepted definitions of classical neuroanatomy in quantitative computerized neuroimaging applications.

Journal ArticleDOI
TL;DR: It is demonstrated that the mean sum of squares test is moresensitive to nonfocal signals and proposed that it could be used to complement approaches that are more sensitive to focal activations.

Journal ArticleDOI
TL;DR: The similarity and multiplicity of the activations in the two tasks suggest that the brain uses a multinodal general network for memory tasks such as free recall, while the differences suggest that some nodes in the network may be used for specific components of memory such as encoding and retrieval.

Journal ArticleDOI
TL;DR: The experimental hypothesis that human occipital visual cortex has retinotopic maps similar to those of the macaque monkey was confirmed and the position of V3 defined by retinal topography was found to correspond to that surmised from previous PET studies employing moving stimuli.

Journal ArticleDOI
TL;DR: The cerebral activation pattern elicited by the perceptual maze test (PMT), a neuropsychological test used to evaluate organic brain injury, was investigated with PET to represent relatively decreased blood flow in cortical areas pertaining to sensory modalities that were not activated in the PMT.

Journal ArticleDOI
TL;DR: A computerized system for brain tissue classification of dual echo MR data is developed, which uses a polychotomous logistic model for discriminant analysis, combined with a Bayes allocation rule incorporating differential prior probabilities, and spatial connectivity tests, to assign each voxel in the image to one of four possible classes: gray matter, white matter, cerebrospinal fluid, or unclassified.

Journal ArticleDOI
TL;DR: A method for mathematically modeling the changes in regional cerebral blood flow (rCBF) as a function of experimental parameters using step and linear functions is presented.

Journal ArticleDOI
TL;DR: The correlates of familiarity measured in this human brain mapping experiment may correspond with what has been measured in single neurons in monkeys, and this correspondence holds both for the type and for the localization of changes.

Journal ArticleDOI
TL;DR: Activations in the temporal lobes previously observed using positron emission tomography and auditory stimuli were partially reproduced with functional MRI and echo-planar imaging at 1.5 T in six volunteers performing tone and phoneme monitoring tasks.

Journal ArticleDOI
TL;DR: A novel image matching algorithm is presented that simultaneously aligns a set of serial sections and uses the method to reconstruct whisker barrels from the rat cerebral cortex and produces superior accuracy.

Journal ArticleDOI
TL;DR: HMSD detection performances of averaged data were better than that obtained with the 2D version of statistical parametric mapping (SPM) and comparable to that of the 3D versions of SPM.

Journal ArticleDOI
TL;DR: The combination of LY injections with immunofluorescence allows the investigation of transmitter-related substances around the LY-injected cells and may contribute to the understanding of different neurological and psychiatric disorders and may be useful in the Mapping of the Human Brain project.

Journal ArticleDOI
TL;DR: QNB is m2-selective in vivo and that a suitably radiolabeled derivative of QNB, possibly labeled with 18F, may be of potential use in positron emission tomographic study of the loss of m2 receptors in AD.

Journal ArticleDOI
TL;DR: Using the AFM it is possible to resolve individual vesicles and follow changes in vesicular structure and opens the possibility that the secretory event can be reconstituted and visualized in vitro in order to elucidate the roles of synaptic proteins in synaptic transmission.


Journal ArticleDOI


Journal ArticleDOI
TL;DR: The rubrocerebellar system of the turtle was three-dimensionally reconstructed to permit detailed examination of its anatomical organization, and was able to mathematically section through the reconstruction to obtain brainstem slices with differing orientations and thickness.