Showing papers in "Neuroscience Letters in 2002"

TL;DR: The results showed that brain and serum BDNF levels underwent similar changes during maturation and aging processes (analysis of variance (ANOVA): P<0.001 and not significant, for hippocampus and platelets, respectively).

TL;DR: Functional magnetic resonance imaging revealed differential activation in the limbic-prefrontal circuit (orbitofrontal cortex, insula, anterior cingulate, amygdala) in the HC, whereas the PP displayed brief amygdala, but no further brain activation, suggesting a hypoactive frontolimbic circuit may represent the neural correlate of psychopathic behavior.

TL;DR: Results indicate that (-)-menthol is endowed with analgesic properties mediated through a selective activation of kappa-opioid receptors.

TL;DR: The results show that SCRs can be evoked and modulated by musical emotional arousal, but are not to emotional clarity.

TL;DR: Ghrelin induces Fos expression selectively in the ventromedial part of the hypothalamic arcuate nucleus (Arc) and indicates that NPY neurons in the Arc are likely the primary target mediating i.p. ghrelin induced orexigenic effect.

TL;DR: Total gray matter volumes were significantly increased in lithium-treated patients compared with untreated patients and healthy individuals, suggesting in vivo effects of lithium on gray matter, which could possibly reflect lithium's neurotrophic effects.

TL;DR: It is suggested that ghrelin acts to regulate food intake through synaptic connections in hypothalamic neuronal networks through synapses with unknown immunonegative neurons.

TL;DR: These results are indicative of changes in the HPA system in insomnia and may reflect a pathophysiological mechanism of chronic insomnia resulting in a vicious cycle of both disturbed HPA functions and chronic insomnia according to the arousal hypothesis of insomnia.

TL;DR: Findings provide a link between mutations or over-expression of alpha-synuclein and apoptosis of dopaminergic neurons by lowering the threshold of these cells to oxidative damage, suggesting the vulnerability of neurons to dopamine-induced cell death through excess intracellular ROS generation.

TL;DR: The data indicate that overexpression of PGP in epileptic tissue is likely to limit brain access of the AEDs phenobarbital, lamotrigine, and felbamate, thus favoring the hypothesis that multidrug transporters play a crucial role in the phenomenon of drug-refractory epilepsy.

TL;DR: The hypothesis that the primary sensorimotor cortex is active during IM and that IM and EM share common functional circuits is supported.

TL;DR: The values of fractional anisotropy were significantly lower in the temporal subcortical white matter, posterior part of the corpus callosum, and anterior and posterior cingulate bundles in patients with AD compared with controls, suggesting selective impairments in the white matter with pathological changes in the posterior cerebral cortices and hippocampus.

TL;DR: Structural and function defects in 26/20S proteasomes may underlie protein accumulation, formation of proteinaceous Lewy bodies and dopaminergic neuronal death in the SNc in sporadic PD.

TL;DR: Preliminary findings indicate that training may be beneficial to LP subjects with brainstem processing delays, and defects in cortical processing of signals in noise were seen for those LPSubjects with delayed brainstem responses to the /da/, but not for LPs with normal brainstem measures.

TL;DR: In this article, diffusion tensor imaging was performed on five adult subjects with musical training since early childhood, and seven adult controls to determine possible differences in white matter architecture, and they hypothesize that these changes are due to the cognitive and motor effects, respectively, of musical training.

TL;DR: Results provide further evidence that the interaction between the circadian system and sleep-wake timing is altered in aging, and suggest that a shortening of circadian period with age cannot account for the advanced circadian phase and earlier wake times of older subjects.

TL;DR: It was observed that male and female subjects used a rather different set of neural correlates when processing faces showing either happy or sad expressions, providing some preliminary support for the speculation that the two genders may be associated with different areas of brain activation during emotion recognition of happy orSad facial expressions.

TL;DR: It is suggested that meditative experience, characterized by less complex dynamics of the EEG, involves 'switching off' irrelevant networks for the maintenance of focused internalized attention and inhibition of inappropriate information.

TL;DR: There was a significant reduction of the volume of the left OFC in patients with ADHD, and magnetic resonance volumetry was used to investigate a possible role of the orbitofrontal cortex (OFC) in this disorder.

TL;DR: Reduced drebrin could be responsible for or representing the loss of spine plasticity in DS and may be a useful indicator for the impaired arborization in neurodegenerative disorders.

TL;DR: Results suggest that the increase in tissue ATP content did not result from the thermal effect, but from a specific effect of the laser operated at the 830-nm wavelength.

TL;DR: It is demonstrated that laser acupuncture of a specific acupoint, empirically related to ophthalmic disorders, leads to activation of visual brain areas, whereas placebo acupuncture does not, indicating that fMRI has the potential to elucidate effects of acupuncture on brain activity.

TL;DR: Data suggest that rTMS of the SMA can modify interhemispheric communication and accordingly modulate interlimb behavior, and showed a deterioration of temporal control as a function of coordinative complexity.

TL;DR: It is suggested that afferent proprioceptive inputs may play a role in the final part of the beta ERD observed during voluntary movements, similar to that observed during ballistic movements.

TL;DR: Preliminary findings indicate an activation of the brain's 'fear network' and underscore the need for examination of body image distortions in anorectic patients with a fMRI design to further evaluate the course of this disturbance in a longitudinal approach.

TL;DR: These findings not only support prior studies indicating that lipid peroxidation is increased in patients with PD and DLBD but that oxidative damage may play a critical role in Lewy body formation.

TL;DR: Loss of COX-2 activity reduces MPTP-induced damage to the dopaminergic neurons of the SNc, but does not alter the levels of dopamine and its metabolites in the striatum, suggesting the possibility that manipulation of the COx-2 could be an important target for therapeutic interventions in PD.

TL;DR: The results suggest that GSK-3beta might function as a possible mediator for regulating both amyloid deposition and tau pathology in Alzheimer's disease (AD), and that lithium should be re-evaluated as a candidate reagent for preventing AD pathology.

TL;DR: The results suggest that the chronic administration of quetiapine could be neuroprotective to hippocampal neurons in schizophrenia and this effect may be related to its antipsychotic effect in patients with schizophrenia.

TL;DR: The reduction in cerebellar cortical NAA/tCR indicates that there is neuronal damage or loss in ET, suggesting that ET may be a neurodegenerative disease.