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Showing papers in "Obstetrics & Gynecology in 2000"


Journal ArticleDOI
TL;DR: Although middle-aged women are highly symptomatic, the symptoms that appear to be specifically related to hormonal changes of menopausal transition are vasomotor symptoms, vaginal dryness, and breast tenderness.

831 citations


Journal ArticleDOI
TL;DR: Depression and anxiety in early pregnancy are associated with risk for subsequent preeclampsia, a risk further increased by bacterial vaginosis.

662 citations


Journal ArticleDOI
TL;DR: Placental apoptosis and altered expression of Fas and Fas ligand in trophoblast might influence pathogenesis or sequelae of preeclampsia.

429 citations


Journal ArticleDOI
TL;DR: Hypertension, especially severe hypertension, was associated with an appreciable increase in important maternal and perinatal morbidity but not per inatal mortality.

427 citations


Journal ArticleDOI
TL;DR: Sleep disturbance was greatest during the first postpartum month, particularly for first-time mothers, and sleep efficiency remained significantly lower than baseline prepregnancy values.

409 citations


Journal ArticleDOI
TL;DR: Severe and early-onset preeclampsia were associated with significant fetal growth restriction, and birth weight reduction related to maternal smoking appeared to be added to that caused by preeClampsia, suggesting that there is no synergy between smoking and preeclampia on growth restriction.

408 citations


Journal ArticleDOI
TL;DR: Diagnostic hysteroscopic procedures had very low complication rates, so are safe procedures with which to evaluate intrauterine pathology, and Operative hysteroscopic operations were more risky, but the removal of polyps had a very high complication rate.

392 citations


Journal ArticleDOI
TL;DR: A meta-analysis of published studies found physically demanding work may significantly increase a woman's risk of adverse pregnancy outcome and found no significant association between long work hours and preterm birth.

375 citations


Journal ArticleDOI
TL;DR: Hemostatic multiple square suturing is an easy, safe, conservative surgical alternative to hysterectomy for treating uncontrollable postpartum hemorrhage and further pregnancy was achieved after this method was used.

346 citations


Journal ArticleDOI
TL;DR: A one-stage color Doppler screening program at 23 weeks identified most women who subsequently developed serious complications of impaired placentation associated with delivery before 34 weeks, and the screening results were similar when the high-risk group was defined as women with increased PI or bilateral notches.

340 citations


Journal ArticleDOI
TL;DR: A retrospective cohort analysis of hemoglobin and birth outcome among 173,031 pregnant women who attended publicly funded health programs in ten states and delivered a liveborn infant highlighted the importance of considering anemia and high hemoglobin level as indicators for adverse pregnancy outcome.

Journal ArticleDOI
TL;DR: Leiomyomas appear to increase likelihood of complications during pregnancy, labor, and delivery.

Journal ArticleDOI
TL;DR: Almost all symptoms assessed were significantly worse during the 7-day hormone-free interval than during the 21 days of hormone-containing pills.

Journal ArticleDOI
TL;DR: Pregnant women less than 18 years old were more likely to deliver preterm than older women and in most other respects they have less maternal and perinatal morbidity and were morelikely to have normal vaginal deliveries.

Journal ArticleDOI
TL;DR: Open laparoscopy was associated with no method failure or life-threatening complications, and is a safe, effective method of access to the abdominal cavity for laparoscopic surgery.

Journal ArticleDOI
TL;DR: A reliable prenatal diagnosis of congenital CMV infection based on PCR on amniocentesis samples can be made after 21 weeks' pregnancy, after a 7-week interval between diagnosis of maternal infection and antenatal procedure.

Journal ArticleDOI
TL;DR: The authors' findings in endometrial tissue specimens from hysterectomies excluded the possibility of contamination by progesterone that remained in the vagina, andRatios ofendometrial to serum progester one concentrations were higher after vaginal administration of progestersone than after IM injections.

Journal ArticleDOI
TL;DR: Several factors associated with an increased risk of unexplained fetal death were identified and identified in this study.

Journal ArticleDOI
TL;DR: Advanced maternal age beyond 25 years was associated with significantly increased risk of fetuses having congenital malformations not caused by aneuploidy, and the risks of clubfoot and diaphragmatic hernia also increased as maternal age increased.

Journal ArticleDOI
TL;DR: Elective induction significantly increased the risk of cesarean delivery for nulliparas, and increased inhospital predelivery time and costs.

Journal ArticleDOI
TL;DR: Elevated homocysteine and reduced serum folate concentrations were risk factors for recurrent spontaneous early pregnancy losses and a significant dose-response relationship between serum folates and risk of recurrent early pregnancy loss suggested a protective effect by high serum folATE concentrations.

Journal ArticleDOI
TL;DR: Low weight gain in pregnancy was associated with increased risk of preterm delivery, particularly if women were underweight or of average weight before pregnancy, and the magnitude of risk varied according to a woman's prepregnancy BMI.

Journal ArticleDOI
TL;DR: Nicotine patches had no influence on smoking cessation during pregnancy, although they might increase birth weight in comparison with placebo.

Journal ArticleDOI
TL;DR: There is no clear consensus regarding the indications for support pessaries compared with space-filling pessARY, or the use of a single pessary for all support defects compared with tailoring the p Tessary to the specific defect.

Journal ArticleDOI
TL;DR: The relationship between serum concentration of group B streptococcal capsular polysaccharide-specific immunoglobulin (Ig) G, colonization status, race or ethnicity, and age in pregnant women was described in this article.

Journal ArticleDOI
TL;DR: In healthy pregnant women, a platelet count over 115 × 109/L late in pregnancy does not require further investigation during pregnancy and may be considered a safe threshold.

Journal ArticleDOI
TL;DR: It is confirmed that platinum-based adjuvant treatments allow most women with ovarian germ cell malignancies to have conservative surgery without compromising survival.

Journal ArticleDOI
TL;DR: Because most PID-related costs arise in the first year from treatment of acute PID infection, strategies that prevent PID are likely to be cost-effective within a single year.

Journal ArticleDOI
TL;DR: Factors shown to increase perineal integrity include avoiding episiotomy, spontaneous or vacuum-assisted rather than forceps birth, and in nulliparas, perineAL massage during the weeks before childbirth.

Journal ArticleDOI
TL;DR: Significant improvements were seen after hysterectomy for all three aspects of health status (symptoms, psychologic function, and quality of life), which persisted or continued to improve throughout the 2 years of follow-up.