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Showing papers in "Ophthalmology in 2003"


Journal ArticleDOI
TL;DR: There seems to be a genuine need for consistent international clinical classification systems for diabetic retinopathy and diabetic macular edema that are supported with solid evidence.

2,665 citations


Journal ArticleDOI
TL;DR: Retrospective review of preoperative and postoperative data for each case compared with that of previously reported cases and cases with uneventful postoperative courses found significant risk factors for the development of ectasia after LASIK include high myopia, forme fruste keratoconus, and low RSB.

584 citations


Journal ArticleDOI
TL;DR: The prevalence of dry eye, although varied according to definition, is relatively higher in this study than that reported for whites, and further studies are needed to determine whether this is due to racial or environmental factors.

562 citations


Journal ArticleDOI
TL;DR: Because triamcinolone pharmacokinetics were characterized only in elderly patients with macular edema, the results cannot be extrapolated to other patient populations.

545 citations


Journal ArticleDOI
TL;DR: The 5-year and 10-year survival rates in this series demonstrate that PKP is a safe and effective treatment for the corneal diseases commonly transplanted in the United States, however, endothelial failure and immunologic graft rejection were persistent risks over the long term, supporting the need for continued patient follow-up.

543 citations


Journal ArticleDOI
TL;DR: Both macular and NFL thickness as measured by OCT showed statistically significant correlations with glaucoma, although NFL thickness showed a stronger association than macular thickness.

519 citations


Journal ArticleDOI
TL;DR: The literature supports the safe and effective use of open-loop anterior chamber, scleral-sutured posterior chamber, and iris-sutanized posterior chamber IOLs for the correction of aphakia in eyes without adequate capsular support for placement of a posterior chamber lens in the capsular bag or ciliary sulcus.

432 citations


Journal ArticleDOI
TL;DR: The mean age-adjusted incidence of uveal melanoma in the United States is similar to that reported from European countries and has remained stable for the past 25 years.

424 citations


Journal ArticleDOI
TL;DR: The prevalence of glaucoma in this population is not lower than that reported for white populations elsewhere, and increasing age, male gender, myopia greater than 1 diopter, and pseudoexfoliation were significantly associated with POAG.

376 citations


Journal ArticleDOI
TL;DR: Six hours of prescribed daily patching produces an improvement in visual acuity that is of similar magnitude to the improvement produced by prescribed full-time patching in treating severe amblyopia in children 3 to less than 7 years of age.

358 citations


Journal ArticleDOI
TL;DR: Although the primary outcome was not statistically significantly in favor of verteporfin therapy at 2 years as it had been at 1 year of follow-up, the distribution of change in visual acuity at the month 24 examination showed that this group was more likely to have improvedVisual acuity through the month24 examination.

Journal ArticleDOI
TL;DR: Findings indicate relationships between higher pulse pressure and systolic blood pressure with an increased 10-year incidence of some lesions defining early age-related maculopathy and exudative macular degeneration.


Journal ArticleDOI
TL;DR: Retinopathy is independently associated with cardiovascular mortality, and associations for other retinal abnormalities were only observed in middle-aged persons, which support recent studies that suggest retinal microvascular abnormalities provide independent information regarding cardiovascular risk.

Journal ArticleDOI
TL;DR: Utilities for the more severe forms of dry eye are in the range of conditions like class III/IV angina and more severe angina that are widely recognized as lowering health utilities.

Journal ArticleDOI
TL;DR: The results suggest that IL-6 and VEGF may promote an increase of vascular permeability in DME subjects without PVD through a paracrine effect on V EGF in these subjects.

Journal ArticleDOI
TL;DR: This paper examined the relation of refractive errors to glaucoma and intraocular pressure (IOP) in a defined white population and found that myopic refraction was correlated with increasing IOP at baseline.

Journal ArticleDOI
TL;DR: It is suggested that retinal microvascular abnormalities reflect processes associated with hypertension but distinct from atherosclerosis, and are common in older persons without diabetes and related to hypertension.

Journal ArticleDOI
TL;DR: It is indicated that active treatments should be recommended to prevent long-term visual impairment in Asian patients with myopic CNV, secondary to the development of chorioretinal atrophy around the regressed CNV.

Journal ArticleDOI
TL;DR: In this article, the authors examined combined photodynamic therapy (PDT) with verteporfin and intravitreal triamcinolone acetonide for choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD).

Journal ArticleDOI
TL;DR: The 5-year cumulative incidence and change in epiretinal membranes in an older Australian population, defined as either preretinal macular fibrosis (PMF), with retinal folds, or as a less severe form, termed cellophane macular reflex (CMR), without retinal fold, is described.

Journal ArticleDOI
TL;DR: In this article, a systematic literature review and meta-analysis of randomized controlled trials was performed to assess the visual effects of multifocal intraocular lenses (IOLs) compared with the current standard treatment of monofocal IOL implantation.

Journal ArticleDOI
TL;DR: It is suggested that ICG has relatively few specific indications for use as justified by previously published peer-reviewed studies and has clear advantage over fluorescein angiography in relatively few chorioretinal disorders.

Journal ArticleDOI
TL;DR: The results support the safety, efficacy, and predictability of ICL implantation to treat moderate to high myopia and suggest an improvement at 1 year over baseline values for the following subjective symptoms.

Journal ArticleDOI
TL;DR: The EN-DCR approach is more rapid than the traditional external approach, has an equivalent surgical success rate, and was preferred by patients who had alternative techniques performed on opposite sides.

Journal ArticleDOI
TL;DR: Patients with retinal vascular anastomosis to the vascular proliferation of exudative AMD were much more likely to have focal areas of intense autofluorescence in their fellow eye that corresponded, for the most part, with focal Areas of hyperpigmentation best seen by infrared monochromatic fundus photography.

Journal ArticleDOI
TL;DR: Evidence is provided that peeling of the ILM during macular pucker surgery may not have deleterious effects, and visual acuity improved or was unchanged in 79% of operated eyes without ILM peeling and 100% ofoperated eyes with ILMpeeling.

Journal ArticleDOI
TL;DR: The incidence of HCQ-related retinopathy in 400 patients who were treated with recommended dosages of the drug for a mean of 8.7 years was reduced to 0.5%, and patients with normal renal function may receive HCQ at a maximal daily dosage of 6.5 mg/kg and continue safely for 6 years.

Journal ArticleDOI
TL;DR: Advances made in the local methods of treatment of primary uveal melanoma have not led to an improvement in survival, and systemic approaches to management of uvea melanoma are warranted.

Journal ArticleDOI
TL;DR: Fibrin glue and cyanoacrylate tissue adhesive are both effective in the closure of corneal perforations up to 3 mm in diameter, but it requires a significantly longer time for adhesive plug formation.