Showing papers in "Ophthalmology in 2005"
TL;DR: Three-dimensional OCT imaging can be performed using high-speed ultrahigh-resolution OCT and may help to elucidate the structural changes associated with retinal disease as well as improve early diagnosis and monitoring of disease progression and response to treatment.
751 citations
TL;DR: Overall, bevacizumab therapy was well tolerated, with an improvement in VA, OCT, and angiographic outcomes, and although these preliminary results are promising, a randomized controlled clinical trial is necessary before concluding that systemic bevicizumAB therapy is safe and effective for patients with neovascular AMD.
666 citations
TL;DR: In this article, the authors describe the association of demographic, behavioral, medical, and non-retinal ocular factors with the incidence of neovascular age-related macular degeneration (AMD) and central geographic atrophy (CGA) in the AREDS, a randomized trial of antioxidants and zinc supplementation prophylaxis for development of advanced AMD.
648 citations
TL;DR: In this phase II trial, subjects assigned to pegaptanib had better VA outcomes, were more likely to show reduction in central retinal thickness, and were deemed less likely to need additional therapy with photocoagulation at follow-up.
578 citations
TL;DR: There is no strong evidence supporting a relation between noncompliance and progression of VF loss among glaucoma patients, and only a few guidelines for clinicians can be derived from the currently available literature.
424 citations
TL;DR: This meta-analysis suggests that bimatoprost, travoprost for glaucoma, latanoprostfor ocular hypertension, and timolol are the most effective intraocular pressure-reducing agents in POAG and OH patients.
413 citations
TL;DR: The EGPS failed to detect a statistically significant difference between medical therapy and placebo in reducing the incidence of POAG among a large population of OHT patients at moderate risk for developing POAG, because placebo also significantly and consistently lowered IOP.
340 citations
TL;DR: Visual impairment in school-age children in urban Gombak District is overwhelmingly caused by myopia, with a particularly high prevalence among children of Chinese ethnicity.
339 citations
TL;DR: In this paper, the authors describe the incidence and types of childhood esotropia in a defined population, including the accommodative and acquired nonaccommodative forms occurring most frequently.
327 citations
TL;DR: Peripapillary NFL thickness, as a total measurement of both macular and peripheral NFL, is still the best surrogate marker in glaucoma assessment and macular NFL thickness was significantly reduced in glAUcoma.
326 citations
TL;DR: Meta-analysis of previously reported data and case series studies found that younger age was significantly associated with triamcinolone-induced ocular hypertension, and these findings may be useful for comparing risks and benefits of intravitreal triaminolone acetonide therapy.
TL;DR: Interleukin-6, TNF-alpha, and MMP-9 are overexpressed in the tears of patients with keratoconus, indicating that the pathogenesis of keratconus may involve chronic inflammatory events.
TL;DR: In this paper, the anterior chamber width and other dimensions relevant to the sizing of phakic intraocular lenses (IOLs) with a high-speed optical coherence tomography (OCT) system were measured.
TL;DR: The sensitivity and specificity of RNFL measurements using the new StratusOCT for glaucoma with manifest VF defects are excellent, and the best parameters seem to be >or=1 quadrants abnormal at the or-1 clock hours abnormal atthe
TL;DR: Analysis of Medicare claims data suggests that the incidence of endophthalmitis after cataract surgery has been increasing, but does not provide an explanation for this occurrence.
TL;DR: Myopia was more prevalent in younger subjects, and myopia was associated with urban region, educational background, female gender, decreasing visual acuity, and nuclear cataract, as in other population-based studies on Chinese.
TL;DR: The success rate of DCR for acquired NLDO in the group of patients was 77%, lower than reported in previous studies, with endoscopic surgery showing better results.
TL;DR: Generalized retinal arteriolar narrowing, an indicator of localized vascular change, is significantly associated with optic nerve damage caused by OAG, and it is not clear whether such a retinalarteriolar change reflects an ischemic process leading to optic nerveDamage or results from loss of retinal neurons secondary to glaucoma.
TL;DR: Retinal vein occlusion and retinal arteriolar emboli are associated with carotid artery disease, hypertension, and other cardiovascular risk factors.
TL;DR: The Tajimi Study determined the prevalence of primary angle-closure glaucoma (PACG), secondary glau coma (SG), and all glAUcoma in a Japanese population as a part of the Tajimi study, a population-based epidemiological survey.
TL;DR: Ultrahigh-resolution OCT images can provide a baseline for defining the interpretation of standard-resolution images, thus enhancing the clinical utility of standard OCT imaging and providing additional information on macular disease morphology that promises to improve understanding of disease progression and management.
TL;DR: Reading performance was better in patients who were not aware of using eccentric viewing strategies and who used a repeatable number of PRLs under all positions of gaze, which are relevant for counseling patients with MD and for the design of rehabilitation programs for patients with central vision loss.
TL;DR: The Trabectome seems to offer a safe and effective method of lowering IOP in OAG and remained stable in all patients beyond 3 weeks postoperatively except one, not sutured at surgery, who had a late hyphema probably associated with corneal wound gaping after accidental blunt trauma.
TL;DR: Microincision cataract surgery significantly lowered mean phacoemulsification time, mean total phacoamulsification percent, mean EPT, and surgically induced astigmatism when compared with coaxial phacomulsification.
TL;DR: Single intravitreal injections of ranibizumab up to a dose of 500 microg were safe and well tolerated in this small group of patients, and the maximum tolerated single dose in neovascular AMD patients was 500microg.
TL;DR: In patients with uveitic CME, intravitreal TA can effectively reduce CME and improve VA and, in some eyes, allows the cessation and/or reduction of immunosuppressive therapy.
TL;DR: The DLEK procedure, with its absence of corneal surface incisions and sutures, preserves the normal corneale topography, minimizes astigmatism, and provides a healthy donor endothelial cell count and function.
TL;DR: Although the number of patients in this pilot study was limited, the improvement of acuity and the reduced treatment frequency in these patients suggest that combination therapy with PDT and intravitreal triamcinolone acetonide, particularly when used as first-line therapy, merits further investigation.
TL;DR: On the basis of OCT data, the RNFL is thickened in E-LHON and severely thinned in A- lHON; the temporal fibers are the first and most severely affected; the nasal fibers seem to be partially spared in the late stage of the disease.
TL;DR: Both the phacoemulsification and the small-incision techniques are safe and effective for visual rehabilitation of cataract patients, although phacoEMulsification gives better uncorrected visual acuity in a larger proportion of patients at 6 weeks.