Showing papers in "Oral Oncology in 1999"

TL;DR: The early surgical intervention, and the withdrawal from oral habits, especially betel quid chewing, will be advantageous to patients' survival, according to retrospectively analyzed the records of oral SCC patients collected from 1 January 1985 to 31 December 1996.

TL;DR: For patients with lymph node metastasis, extracapsular spread was an important indicator of tumour behaviour and it is recommended its use as a criterion for pathological N staging.

TL;DR: Immunohistochemical and ultrastructural findings have revealed that the eosinophilic deposits or "tumour-droplets" most probably represent some form of enamel matrix, which strongly indicate the AOT is derived from the complex system of dental laminae or its remnants.

TL;DR: It is increasingly apparent that tumour cells, as well as producing endogenous MMP, are capable of utilising MMP produced by tumour stromal cells, indicating an active role for stroma in tumour invasion.

TL;DR: A strong positive association with protein intake was observed, whereas antioxidants were associated with an inverse association and non-nutritive substances, like flavonoids displayed a marked reduction in risk of 70%.

TL;DR: There was a significant deterioration of physical functioning, fatigue and almost all head and neck symptoms except pain, which improved, and there is an improvement of emotional functioning after treatment, probably as a result of adaptation and coping processes.

TL;DR: Within the histologic spectrum that is seen in PVL, usually as a function of time, are: verrucous hyperplasia (VH), a histologically defined lesion; (2) varying degrees of dysplasia; and (3) three forms of squamous cell carcinoma: verRucous, conventional and, according to some, papillary squamouscell carcinoma.

TL;DR: No agent has been shown to be uniformly efficacious and can be accepted as standard therapy of chemotherapy- and radiotherapy-induced oral mucositis, but anti-inflammatory drugs might be beneficial.

TL;DR: The palliative effects of Oral Balance gel and Biotene toothpaste were superior to the effects of a placebo and no effect on oral colonization by Candida species and cariogenic oral microflora was seen with use of the topical agents.

TL;DR: It is concluded that, while tobacco and alcohol synergistically influence the development of OED, exclusive tobacco consumption is more likely than exclusive alcohol consumption to give rise to OED.

TL;DR: Ameloblastic fibro-odontoma is a lesion similar to AF, but also showing inductive changes that lead to the formation of both dentin and enamel, and in revised WHO's classification of odontogenic tumors, the terms "ameloblastic Fibrodentinoma" and "dentinomas" are used synonymously.

TL;DR: Data show that cell cycle regulatory proteins are altered in both premalignant and malignant disease, and that protein phenotypes are heterogeneous.

TL;DR: The present study confirms, the exceptionally high incidence of multifocal SCC in oral cancer patients and emphasizes the importance of preventive measures, since careful screening procedures, carried out to detect multifocal tumours at an early stage, should improve survival in these patients.

TL;DR: The results indicate that the rare homozygote of CYP1A1, m2/m2, is associated with increased risk of oral SCC, in particular, at low cigarette dose levels, and suggested that the involvement of such susceptibility in oral carcinogenesis might be different between the subsites of the oral cavity.

TL;DR: The degree of radiation affects the extent of the depression of the antioxidant enzyme activities and increases lipid peroxidation, thereby rendering the system inefficient in management of the free radical attack.

TL;DR: Investigation of the relationship between proliferative capacity, represented by the immunohistochemical labeling index of proliferation markers Ki-67, PCNA and p53 status, and treatment failure in a matched-pair study design of recurrent and non-recurrent carcinoma found no relationship between p53 or PCNA status and tumor prognosis.

TL;DR: Reducing alcohol and saturated fat intake and increasing fruit and carrot consumption may have favorable effects on oral and pharyngeal cancer risk, even in the absence of smoking.

TL;DR: Salted meat, a possible source of nitrosamines, was associated with an increased risk of 60% for esophageal cancer and a strong association with red meat intake was observed.

TL;DR: Observations suggest that the orally administered extract of O. sanctum may have the ability to prevent the early events of carcinogenesis.

TL;DR: The clinically unilateral atrophic/erosive type of OLP more often preceded the malignant change, compared to the situation for control patients, in whom the most prevalent type was the bilateral reticular OLP.

TL;DR: The overall p53 alterations in oral cancer tissues and oral lesions are comparable to data from the oral cancers reported in the Western countries with smoking and alcohol-associated oral cancers, and suggest a critical role for p53 gene in a significant proportion of oral cancers from India.

TL;DR: A strong correlation was noted between the incidence of oral cancer and local authorities with a high percentage of Asian residents and south Asian and Chinese ethnic minorities constitute important high risk groups for oral and nasopharyngeal cancer, for whom targeted prevention is indicated.

TL;DR: Data show that apoptosis-associated proteins are altered in variable patterns in both premalignant and malignant oral epithelial lesions of oral squamous cell carcinoma, and p53 and especially Bak and Bcl-X are expressed early; Bax is largely absent; and B cl-2 and mdm-2 show sporadic expression in the development of oral premalign andmalignant disease.

TL;DR: In this paper, the expression of MDM2 protein in betel and tobacco related oral malignancies in Indian population, its relationship to clinicopathological parameters and p53 protein expression was investigated.

TL;DR: The following case reports concern malignant melanoma of the oral cavity seen at the Instituto Nacional de Cancerología, Mexico City, during the period of 1982-96, with a mean age of 52 years.

TL;DR: It is demonstrated that unilateral neck parotid-sparing techniques are effective in preserving contralateralParotid glands up to 2 years after the completion of RT.

TL;DR: Radiotherapy using 55 Gy or more combined with operation achieved local control and survival rates comparable with complete resection of tumors even if a positive surgical margin was more frequent in the radiotherapy groups.

TL;DR: The results showed that better performance, up to sensitivity 81.25%, specificity 93.75%, and positive predictive value 92.86%, could be achieved by using the double excitation wavelengths.

TL;DR: A case of angiolymphoid hyperplasia with eosinophilia is described, the problems of histological differential diagnosis between ALHE and other diseases of the region are discussed and the literature is reviewed.

TL;DR: P21 protein was overexpressed in oral SCCs, and this overexpression was related to cell proliferation index and mdm2 expression but independent of p53 protein alteration, and appeared to be insufficient to suppress tumor progression.