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JournalISSN: 1523-7052

Organic Letters

About: Organic Letters is an academic journal. The journal publishes majorly in the area(s): Enantioselective synthesis & Aryl. It has an ISSN identifier of 1523-7052. Over the lifetime, 34256 publication(s) have been published receiving 1324803 citation(s). The journal is also known as: Org. Lett.. more

Topics: Enantioselective synthesis, Aryl, Catalysis more

Journal ArticleDOI: 10.1021/OL990909Q
13 Aug 1999-Organic Letters
Abstract: A new family of 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene-substituted ruthenium-based complexes 9a−c has been prepared starting from RuCl2(CHPh)(PCy3)2 2. These air- and water-tolerant complexes were shown to exhibit an increased ring-closing metathesis activity at elevated temperature when compared to that of the parent complex 2 and the previously developed complex 3. In many instances the activity of these complexes also rivaled or exceeded that of the alkoxy−imido molybdenum complex 1. Catalyst loadings of as low as 0.05 mol % could be used. more

3,023 Citations

Journal ArticleDOI: 10.1021/OL0493094
30 Jul 2004-Organic Letters
Abstract: Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes. The C3-symmetric derivative, TBTA, was shown to be a powerful stabilizing ligand for copper(I), protecting it from oxidation and disproportionation, while enhancing its catalytic activity. more

Topics: Derivative (chemistry) (59%), Ligand (56%), Disproportionation (52%) more

1,284 Citations

Journal ArticleDOI: 10.1021/OL050431S
14 Apr 2005-Organic Letters
Abstract: Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields. more

Topics: Cinchona Alkaloids (57%), Michael reaction (54%), Thiourea organocatalysis (53%) more

845 Citations

Journal ArticleDOI: 10.1021/OL016217V
09 Aug 2001-Organic Letters
Abstract: Analysis of the basic π-aromatic (benzene) and antiaromatic (cyclobutadiene) systems by dissected nucleus-independent chemical shifts (NICS) shows the contrasting diatropic and paratropic effects, but also reveals subtleties and unexpected details. more

Topics: Antiaromaticity (66%), Aromaticity (59%), Cyclobutadiene (56%) more

807 Citations

Journal ArticleDOI: 10.1021/OL0529546
02 Feb 2006-Organic Letters
Abstract: Five increasingly sophisticated aromaticity indexes, based on nucleus-independent chemical shifts (NICS), were evaluated against a uniform set of aromatic stabilization energies (ASE) for 75 mono- and polyheterocyclic five-membered rings. While acceptable statistical correlations were given by all of the NICS methods, the most fundamentally grounded index, NICS(0)pizz (based on the pi contribution to the out-of-plane zz tensor component), performed best statistically (cc=0.980) and in practice. The easily computable NICS(1)zz index is a useful alternative (cc=0.968). more

Topics: Möbius aromaticity (51%)

757 Citations

No. of papers from the Journal in previous years

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Journal's top 5 most impactful authors

Paul Knochel

97 papers, 4.1K citations

Mark Lautens

80 papers, 4K citations

Janine Cossy

74 papers, 2.3K citations

Xumu Zhang

51 papers, 1.7K citations

Barry M. Trost

38 papers, 1.7K citations

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