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Showing papers in "Pediatric Infectious Disease in 1984"


Journal ArticleDOI
TL;DR: Pertussis (whooping cough), a two-stage process of disease (respiratory colonization and toxin-mediated disease) is caused by B. pertussis, a pathogenic parasite with habitat only in human beings.

244 citations


Journal ArticleDOI
TL;DR: The cause of the epidemic was not discovered but shellfish and raw fish consumption may have played a part and Pacific Island Polynesians were rectal carriers of L. monocytogenes and were represented among the epidemic cases more often than expected according to birth data.

177 citations




Journal ArticleDOI
TL;DR: Two hundred fifty-eight isolates of Streptococcus pneumoniae obtained from 232 infants and children at Children's Medical Center, Dallas, from November 1, 1981, to March 31, 1983, were screened for susceptibility to penicillin.

119 citations


Journal ArticleDOI
Losonsky Ga1, Mathuram Santosham1, Sehgal Vm1, Zwahlen A1, Moxon Er1 
TL;DR: In the prospective surveillance, H. influenzae isolates from cases of systemic disease were further characterized by capsular type, biotype and by outer membrane protein (OMP) and lipopolysaccharide (LPS) patterns on sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE).

108 citations


Journal ArticleDOI
TL;DR: This study confirmed the clinical impression of physicians that specific antibiotic therapy promptly alleviates symptoms in most children with streptococcal pharyngitis.

99 citations


Journal ArticleDOI
TL;DR: Acute lower respiratory infection was associated commonly with viruses, often with multiple pathogens but not with C. trachomatis after 4 months of age, and those with bacteria were significantly more likely to have fever, a band count over 2000/mm3 and radiographic consolidation.

93 citations


Journal ArticleDOI
TL;DR: Cephalexin therapy did not result in a decrease in cultivation of pathogenic organisms from the nasopharynx and significantly more side effects were attributed to pseudoephedrine/triprolidine treatment than to placebo.

81 citations


Journal ArticleDOI
TL;DR: Clinical and laboratory data of 12 previously healthy infants under 3 months of age hospitalized for suspected sepsis and subsequently diagnosed as suffering from influenza A viral infection were obtained prospectively during two epidemics of influenza A/Bangkok/H3N2 epidemics.

62 citations



Journal ArticleDOI
TL;DR: It is recommended that vancomycin and an aminoglycoside be the initial empiric therapy for suspected catheter-associated sepsis and Lack of defervescence or continued positive blood cultures for 2 to 4 days despite antibiotics are indications for catheter removal.




Journal ArticleDOI
TL;DR: Haemophilus influenzae meningitis in children 0 to 15 years old was studied retrospectively in a defined region of southwest Sweden from 1971 through 1980 and two patients died, 3 developed severe neurological sequelae and 19 developed irreversible auditory impairment.

Journal ArticleDOI
TL;DR: The large incidence of acute epiglottitis in children 0 to 15 years old in a defined region of southwest Sweden from 1971 through 1980 emphasizes the importance of H. influenzae in older children.

Journal ArticleDOI
TL;DR: It is suggested that the diagnostic and therapeutic approach to the febrile, granulocytopenic patient who develops a new pulmonary infiltrate while receiving broad spectrum antibiotic therapy may be guided by the state of marrow recovery at the time of infiltrate appearance.

Journal ArticleDOI
TL;DR: The isolation of C. trachomatis from a rectogenital site was not limited to children with recent sexual abuse in this population, and serologic evidence of recent chlamydial infection was present in 5% of controls.

Journal ArticleDOI
TL;DR: The duration nor the patterns of fever correlated with neurologic abnormalities at discharge, including hearing deficit, and the principal conditions associated with persistent fever were nosocomial infections and subdural effusion.


Journal ArticleDOI
TL;DR: The overall case fatality rate was 50% eight of the nine patients with acute leukemia or aplastic anemia died and with the exception of one child the blood cultures were sterile in all patients before death.

Journal ArticleDOI
TL;DR: Postmortem cultures appeared to be helpful in identifying NICU patients in whom serious infection may have played a role in mortality, and unsuspected serious infection is a common finding in infants who die in a neonatal intensive care setting.

Journal ArticleDOI
TL;DR: Intravenous antibiotic therapy in ambulatory patients can provide a successful, safe, cost-effective alternative to inpatient care under conditions of diligent patient screening and physician-centered follow-up.

Journal ArticleDOI
TL;DR: This method of blood collection and testing is an accurate, feasible and acceptable means for seroconfirmation of measles.

Journal ArticleDOI
TL;DR: Most neonates with severe peripheral neutropenia and clinical sepsis had peripheral neutrophil recovery and survived with conservative management, and those at high risk could be identified only by examination of the NSP.

Journal ArticleDOI
TL;DR: Among female employees at a pediatric hospital the risk of cytomegalovirus is substantial and appears to be related to the type of patient contact.

Journal ArticleDOI
TL;DR: In the United States, Salmonella organisms of various species have developed simultaneous resistance to ampicillin, chloramphenicol and trimethoprim-sulfamethoxazole as discussed by the authors.

Journal ArticleDOI
TL;DR: Series: Infectious Disease and the Office Laboratory.

Journal ArticleDOI
TL;DR: While specific therapy is not always available, early diagnosis of ocular viral disease should aid in the amelioration of acute symptoms and prevention of long term complications.