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Showing papers in "Pediatric Infectious Disease in 1986"



Journal ArticleDOI
TL;DR: All antibiotic regimens led to a pronounced suppression of anaerobic flora and overgrowth of Klebsiella but not with other gram-negative aerobic bacteria, including some penicillins usually regarded as relatively harmless in this respect in adults.

150 citations


Journal ArticleDOI
TL;DR: The results support the current view that present pneumococcal polysaccharide vaccines are not beneficial in children younger than 2 years of age and stress the importance of attempts to improve their immunogenicity.

145 citations


Journal ArticleDOI
TL;DR: Development of sequelae was significantly associated with infection at age less than 6 months, delay of 4 or more days in institution of medical or surgery treatment, infection due to S. aureus and most strikingly the involvement of the hip or shoulder with concomitant presence of osteomyelitis.

143 citations


Journal ArticleDOI
TL;DR: The antibody levels to most pneumococcal types decreased rapidly after both injections of the vaccine and the generally poor immunogen types 6A and 23F elicited a weak antibody response mainly in the immunoglobulin M class.

138 citations


Journal ArticleDOI
TL;DR: The majority of infections could be accounted for by a small number of serotypes, with types 3, 6, 14, 19 and 23 predominating and most infections occurred in infants younger than 2 years of age.

136 citations


Journal ArticleDOI
TL;DR: It is suggested that in nurseries where the infection rate is high, prophylactic intravenous polyvalent immunoglobulin therapy for the preterm and low birth weight infants may provide protection from infection.

123 citations



Journal ArticleDOI
TL;DR: The results suggest that facultative gram-negative enteric bacterial colonization, with either total or aminoglycoside-resistant strains, is not decreased by oral feedings of Lactobacillus acidophilus in premature infants.

117 citations



Journal ArticleDOI
TL;DR: It appears to be unnecessary to remove the Silastic catheter automatically just because the patient is febrile, particularly if there is no microbiological evidence that the catheter is the source of the fever, and it is recommended that routine handling of theCatheter be done with aseptic technique, which usually requires use of Betadine swabs when manipulating the Catheter tip.


Journal ArticleDOI
TL;DR: Logistic regression analysis indicated that the model that best fit the observed data included the following risk factors for fungemia: duration of umbilical artery catheterization; duration of receipt of parenteral nutrition; and estimated gestational age.

Journal ArticleDOI
TL;DR: Oral antibiotics prior to admission do not alter the CSF findings in most patients such that a diagnosis of H. influenzae type b meningitis cannot be established and are associated with an increased likelihood of some neurologic sequelae, in part related to a longer duration of illness noted in pretreated patients before definitive therapy when compared to untreated patients.

Journal ArticleDOI
TL;DR: The results show that anemia was commonly associated with the usually mild infections that are typically seen in a pediatric primary care setting and could be inferred to be reversible and unrelated to iron deficiency in most cases.


Journal ArticleDOI
TL;DR: Prospects appear good that an improved second generation vaccine that will provide protective efficacy in infants during the first year of life will become available in the near future.


Journal ArticleDOI
TL;DR: To achieve a better therapeutic outcome for infants with neonatal herpes, consideration should be given to the initiation of antiviral therapy on presumptive clinical and epidemiologic grounds.

Journal ArticleDOI
TL;DR: It is concluded that antibiotic therapy, administered as described here, without simultaneous catheter removal successfully eradicates catheter-related infections.

Journal ArticleDOI
TL;DR: There was no evidence of transmissibility of RRV, by either stool excretion or seroconversion, in the eight infants who participated in the vaccine trial in the day care setting and further work is proceeding to evaluate this vaccine at lower doses in this age group of infants.

Journal ArticleDOI
TL;DR: Twenty-six pediatric patients with osteomyelitis caused by anaerobic bacteria are presented and the etiologic factors were chronic mastoiditis, decubitus ulcers, chronic sinusitis, periodontal abscesses, bites, paronychia, trauma and scalp infection after fetal monitoring.

Journal ArticleDOI
TL;DR: The results indicate that medical therapy, based on the results of culture and susceptibility studies, provides a viable alternative to major mastoid surgery in the management of chronic suppurative otitis media without cholesteatoma.

Journal ArticleDOI
TL;DR: Ceftriaxone, when given in a single daily dose, appears safe and effective in the treatment of bacterial meningitis in nonneonatal infants and children.

Journal ArticleDOI
TL;DR: It is concluded that cefotaxime has similar efficacy when compared with conventional therapy for the management of bacterial meningitis in pediatric patients.

Journal ArticleDOI
TL;DR: The results of this survey indicate that CMV was frequently transmitted to parents from children who had acquired the virus at the day care center.

Journal ArticleDOI
TL;DR: It is concluded that the oral cephalosporins appear to be more effective than penicillin for therapy of Group A streptococcal pharyngitis.

Journal ArticleDOI
TL;DR: Of 57 patients with pathogens isolated 55 were completely cured; in one patient with Klebsiella pneumoniae ventriculitis, intraventricular gentamicin was briefly added to the regimen.

Journal ArticleDOI
TL;DR: Serologic responsiveness, ureaPLasmemia and isolation of ureaplasmas in pure culture from amniotic fluid of some asymptomatic women suggest that U. urealyticum may also be a cause of clinically silent amnionitis.

Journal ArticleDOI
TL;DR: It is document that rotavirus infection can be transmitted by aerosol droplets under experimental conditions and Gastrointestinal illness was clearly demonstrable in the animals while pulmonary pathology was not evident.