Pharmacognosy Magazine 

About: Pharmacognosy Magazine is an academic journal published by Medknow. The journal publishes majorly in the area(s): DPPH & Apoptosis. It has an ISSN identifier of 0973-1296. Over the lifetime, 1788 publications have been published receiving 24272 citations. The journal is also known as: Phcog. Mag..

Comparative study of rosmarinic acid content in some plants of Labiatae family.

Abstract: Background: Plants of Labiatae are used in traditional medicine and phytotherapy. Rosmarinic acid (RA) is a phenolic compound which is found in many genus of Labiatae and exhibits important biological activities. Materials and Methods: In this investigation, RA contents of 29 species of Labiatae named Salvia officinalis, Salvia limbata, Salvia virgata, Salvia hypoleuca, Salvia macrosiphon, Salvia choloroleuca, Melissa officinalis, Origanum vulgare, Lavandula angustifolia, Rosmarinus officinalis, Thymus daenensis, Thymus citriodorous, Thymus pubescens, Thymus vulgaris, Zataria multiflora, Mentha piperita, Mentha pulegium, Mentha longifolia, Mentha spicata, Mentha aquatica, Mentha crispa, Perovskia artemisoides, Zhumeria majdae, Satureja hortensis, Satureja khuzistanica, Satureja bachtiarica, Satureja atropatana, Satureja mutica and Satureja macrantha were determined by using high-performance liquid chromatographic method. Results: The results showed that RA content in different species of Labiatae was 0.0-58.5 mg g -1 of dried plants. The highest amount of RA was found in Mentha species especially M. spicata. Conclusion: M. spicata can be considered as a new source of rosmarinic acid .

In vitro Antioxidant and Free Radical Scavenging Activity of Diospyros lotus and Pyrus boissieriana growing in Iran

Abstract: Current research into free radicals has confirmed that foods rich in antioxidants play an essential role in the prevention of many diseases The potential antioxidant activities of Diospyros lotus and Pyrus boissieriana fruits investigated employing six in vitro assay systems IC 50 for DPPH radical-scavenging activity was 145 ± 003 for D lotus and 30 ± 004 mg ml -1 for P boissieriana, respectively The extracts showed weak nitric oxide-scavenging and Fe 2* chelating ability activity The D lotus extracts was better than P boissieriana The peroxidation inhibition of D lotus and P boissieriana extracts exhibited values from 89 (at 24 th ) to 94% (at 72 nd hrs) and 91 to 95% respectively Neither of them showed good scavenging activity of H 2 0 2 The total amount of phenolic compounds in each extracts was determined as gallic acid equivalents and total flavonoid contents were calculated as quercetin equivalents from a calibration curve Both of them had high total phenolic and flavonoid contents

Phytochemical investigation and antimicrobial activity of Psidium guajava L. leaves.

Abstract: Psidium guajava L. leaves were subjected to extraction, fractionation and isolation of the flavonoidal compounds. Five flavonoidal compounds were isolated which are quercetin, quercetin-3-O-α-L-arabinofuranoside, quercetin-3-O-β-D-arabinopyranoside, quercetin-3-O-β-D-glucoside and quercetin-3-O-β-D-galactoside. Quercetin-3-O-β-D-arabinopyranoside was isolated for the first time from the leaves. Fractions together with the isolates were tested for their antimicrobial activity. The antimicrobial studies showed good activities for the extracts and the isolated compounds.

Antioxidant activity of aqueous and ethanolic extracts of Crocus sativus L. stigma and its bioactive constituents, crocin and safranal

Abstract: The antioxidant activity of aqueous and ethanol extracts of saffron (Crocus sativus L.) stigma and its constituents, crocin and safranal were evaluated using deoxyribose, erythrocyte membrane lipid peroxidation and liver microsomal non-enzymatic lipid peroxidation methods in vitro. The aqueous and ethanolic extracts in different concentrations (10, 100, 250, 500 and 1000 µg/ml), crocin and safranal at 0.1, 0.5, 1 and 2 mM were tested. Results showed that test compounds could diminish the extent of MDA generation in three methods (P 0.05). Crocin the main carotenoid in saffron extracts probably and relatively safranal may have an important role in antioxidant properties of the extracts.