Showing papers in "Phosphorus Sulfur and Silicon and The Related Elements in 2017"
TL;DR: Organophosphorus compounds have all along attracted considerable attention as they have broad utilities such as reagents for chemical reactions, ligands for transition metal catalysts, flame retard, etc.
Abstract: Organophosphorus compounds have all along attracted considerable attention as they have broad utilities such as reagents for chemical reactions, ligands for transition metal catalysts, flame retard...
68 citations
TL;DR: Tris(tetraalkyl ammonium tribromide) immobilized on Fe3O4 magnetic nanoparticles is a stable, green and magnetically recoverable source of bromine and used as an efficient nanocatalyst for the clean and rapid oxidation of sulfides to sulfoxides using hydrogen peroxide (H2O2) under solvent free conditions as mentioned in this paper.
Abstract: Tris(tetraalkyl ammonium tribromide) immobilized on Fe3O4 magnetic nanoparticles (Br3-Fe3O4) is a stable, green and magnetically recoverable source of bromine and used as an efficient nanocatalyst for the clean and rapid oxidation of sulfides to sulfoxides using hydrogen peroxide (H2O2), with short reaction times in good to high yields under solvent free conditions. After completing reactions, the catalyst was easily separated using an external magnetic field from the reaction mixture and reused for several consecutive runs without significant loss of its catalytic efficiency. The nanomagnetically catalyst was characterized by FT-IR spectroscopy, TGA, VSM, XRD, TEM and SEM.
34 citations
TL;DR: In this article, the synthesis of hetaryl and ferrocenyl thioketones as well as applications of this class of organic sulfur compounds in the synthesis synthesis of both sulfur-containing and sulfur-free organic products are summarized.
Abstract: Methods for the synthesis of hetaryl and ferrocenyl thioketones as well as applications of this class of organic sulfur compounds in the synthesis of both sulfur-containing and sulfur-free organic products are summarized The most important applications relate to [2+2]-, [3+2]-, and [4+2]-cycloadditions Aromatic thioketones react with diazomethane at −70°C, and the formed 1,3,4-thiadiazolines can be used as convenient precursors of reactive thiocarbonyl S-methanides In contrast, the hetaryl thioketones do not form this type of cycloadducts Reactions of hetaryl thioketones with thiocarbonyl S-methanides are proposed to occur via a stepwise diradical mechanism Aryl and hetaryl thioketones react as prone heterodienophiles with cyclic and acyclic dienes The first asymmetric synthesis of dihydrothiopyranes from aryl and hetaryl thioketones was performed using a L-proline-derived organocatalyst Hetaryl thiochalcones are useful heterodienes for the preparation of hetaryl-substituted dihydrothiopyrans
30 citations
TL;DR: In this paper, linear and cyclic chalcogen-containing compounds have been synthesized exploiting the reactivity of bis(trimethylsilyl)selenide with strained heterocycles.
Abstract: New linear and cyclic chalcogen-containing compounds have been synthesized exploiting the reactivity of bis(trimethylsilyl)selenide with strained heterocycles. A simple and efficient procedure allo...
27 citations
TL;DR: The substitution reactions of 2-trans-6-bis(4-fluorobenzyl)spirocyclotetraphosphazene (3; with a yield of 59%) are carried out with excess alkylamines, benzylamine, n-hexylamine and n-butylamine as discussed by the authors.
Abstract: The substitution reactions of 2-trans-6-bis(4-fluorobenzyl)spirocyclotetraphosphazene (3; with a yield of 59%) are carried out with excess alkylamines, benzylamine, n-hexylamine, n-butylamine, n-pr...
22 citations
TL;DR: In this paper, the substitution of chlorine atoms of hexachlorocyclotriphosphazene via the reaction with sodium phenolates of halo groups was described.
Abstract: Hydroxyaryloxycyclophosphazenes containing 2–4 OH groups have been synthesized by the substitution of chlorine atoms of hexachlorocyclotriphosphazene via the reaction with sodium phenolates of halo...
20 citations
TL;DR: In this article, the QSAR studies indicated that antimicrobial activity of target compounds is governed by total energy of molecule and topological descriptors, and the ligands and their organotin complexes have been evaluated for antimicrobial action.
Abstract: Organotin complexes of type R2SnClL [where L = Schiff base obtained by the condensation of 2-(4-Bromo/Chloro-benzyloxy)-3-methoxy-benzaldehyde and nicotinic/isonicotinic hydrazides; R = Me, Et, Bu, and Ph] have been synthesized and characterized by elemental analysis, molar conductance, infrared and NMR (1H, 13C, and 119Sn) spectral analyses. The ligands and their organotin complexes have been evaluated for antimicrobial activity and the QSAR studies indicated that antimicrobial activity of target compounds is governed by total energy of molecule and topological descriptors.
19 citations
TL;DR: An expeditious green synthetic approach was developed for the synthesis of α-aminophosphonates in good yields through one-pot three component reaction (Kabachnik-Fields reaction) of equimolar quantization.
Abstract: An expeditious green synthetic approach was developed for the synthesis of α-aminophosphonates in good yields through one-pot three component reaction (Kabachnik-Fields reaction) of equimolar quant...
19 citations
TL;DR: The Scientific & Technological Research Council of Turkey (TUBITAK) (Project Number: 115Z101) as discussed by the authors is a project of the Turkish National Research Council (TURITAK).
Abstract: The Scientific & Technological Research Council of Turkey (TUBITAK) (Project Number: 115Z101).
18 citations
TL;DR: Most of the synthesized compounds were relatively active with the standard drugs especially in Gram positive bacteria and fungal strains and were screened for antimicrobial activity against four bacterial strains.
Abstract: A series of 16 pentacoordinated diorganotin(IV) complexes has been reported here which were synthesized by reacting the appropriate dialkyl/diaryltin(IV)dichloride with four newly synthesized Schif...
17 citations
TL;DR: A series of novel a-aminophosphonates containing 6-fluorobenzothiazole derivatives were synthesized by one-pot reaction under microwave irradiation and their structures were characterized by as discussed by the authors.
Abstract: A series of novel a-aminophosphonates containing 6-fluorobenzothiazole moiety derivatives were synthesized by one-pot reaction under microwave irradiation and their structures were characterized by...
TL;DR: In this paper, the authors describe advances and achievements, particularly the contributions of the recent years, in synthesis and applications of α-monofluoro-, α,α-difluoro- or trifluor...
Abstract: The goal of this mini review is to describe advances and achievements, particularly the contributions of the recent years, in synthesis and applications of α-monofluoro-, α,α-difluoro- or trifluoro...
TL;DR: All the title compounds were characterized by spectral and elemental analysis and exhibited good antibacterial and antifungal activities compared to the standard bactericide, Penicillin and fungicide, Griseofulvin, respectively.
Abstract: GRAPHICAL ABSTRACT ABSTRACT A facile synthesis of novel α-aminophosphonates 5a-j was accomplished by condensation of imines (3a-j) with diethyl phosphite (4) in ethanol at 50–60°C using easily recoverable and reusable catalyst, tetramethyl guanidine (TMG) via pudovik reaction in high yields. All the title compounds were characterized by spectral and elemental analysis. They were further screened for their abilities towards in vitro antibacterial, antifungal and antioxidant activities. The compounds 5g, 5d, 5f exhibited good antibacterial and antifungal activities compared to the standard bactericide, Penicillin and fungicide, Griseofulvin, respectively. The compounds 5h, 5i, 5g, and 5c exhibited good antioxidant activity compared to the standard ascorbic acid.
TL;DR: The results of in vitro anti-Candida activity, a docking study and ADME prediction revealed that the newly synthesized compounds have potential anti-candida activity and evidenced the most active derivative, 5b (2-Pyrrolidinthiocarbonylthio-N-[4-((1H-imidazol-1-yl)methyl)phenyl]acetamide), which can be further optimized as a lead compound.
Abstract: The incidence of infection from opportunistic and pathogenic fungi has continued to rise in recent years. [...]
TL;DR: In this paper, the synthesis of α-aminophosphonate derivatives via Kabachnik-Fields reaction between an amine, quinoline-4-carbaldehyde and a phosphite in the presence of polyethylene imine is described.
Abstract: Synthesis of some quinoline-containing α-aminophosphonate derivatives via Kabachnik–Fields reaction between an amine, quinoline-4-carbaldehyde and a phosphite in the presence of polyethylene imine ...
TL;DR: A green chemistry route for dithiophosphonic acids of the type [HS2P(OR)(4-MeOC6H4] [R = H, (1); Me (2); Et (3); iPr (4)] was reported in this article.
Abstract: GRAPHICAL ABSTRACT ABSTRACT We report a green chemistry route for dithiophosphonic acids of the type [HS2P(OR)(4-MeOC6H4)] [R = H, (1); Me (2); Et (3); iPr (4)]. The different dithiophosphonic acids formed through the stoichiometric addition of water or alcohols to Lawesson's Reagent (molar ratio 2:1), followed by an intimate grinding of the mixture (mechanochemistry). The products formed without the use of solvent or external heat in less than 5 minutes. The acids are formed with 100% atom economy, and because they form in essentially quantitative yield, are also formed with >98% atom efficiency and an E-factor = 0, because no waste is produced. Of importance is that this methodology is different from conventional methods in forming dithiophosphonic acids where the use of organic solvents, added heat, long reaction times and lower yields are commonplace. We further demonstrate that nickel(II) complexes can form directly from the in situ generated acids. Thus, the reaction between 1–4 and NiCl2 ‧ 6 H2O (molar ratio 2:1) lead to complexes of the type [Ni{S2P(OR)(4-MeOC6H4)}2] [R = H, (5); Me (6); Et (7); iPr (8)] with no use of organic solvent. All compounds were characterized or verified by a combination of 1H, 31P NMR, elemental analysis (solids), and FT-IR.
TL;DR: The present study was undertaken to synthesize some novel lipophilic piperazine and piperidinedithiocarbamates and investigate their inhibitory potencies against cholinesterase enzymes and it was observed that some of the compounds selectively inhibit AChE.
Abstract: GRAPHICAL ABSTRACT ABSTRACT The present study was undertaken to synthesize some novel lipophilic piperazine and piperidinedithiocarbamates and investigate their inhibitory potencies against cholinesterase enzymes. In the synthetic studies, 44 new compounds were isolated. The structures of the synthesized compounds were confirmed by spectroscopic analyses. Enzymatic studies were carried out using modified Ellman's assay against Acetylcholinesterase (AChE) and Butrylcholinesterase (BChE) enzymes, and it was observed that some of the compounds selectively inhibit AChE. Theoretical ADME predictions were calculated for selected compounds in the series. Enzyme kinetics and molecular docking studies were performed for the most active compound C41 and nature of inhibition and interactions between enzyme and ligand were explained.
TL;DR: In this article, thermodynamic calculations were conducted to investigate K-feldspar fluxing yellow phosphorus produced via an electric furnace, and the results demonstrated that the reaction temperature of K-field as a flux was lower than that during the traditional process.
Abstract: GRAPHICAL ABSTRACT ABSTRACT In this study, thermodynamic calculations were conducted to investigate K-feldspar fluxing yellow phosphorus produced via an electric furnace. The results demonstrated that the reaction temperature of K-feldspar as a flux was lower than that during the traditional process. The characteristic temperatures of silica-CaO and potassium feldspar-CaO systems under different mass ratios of SiO2/CaO were measured according to the CaO-substituting decomposition products of phosphorus; the results showed that the temperature of the silica-CaO system was higher, 96.2–114.3°C, compared to the potassium feldspar-CaO system under the same conditions. These results indicate that K-feldspar as a flux in a phosphorus furnace can save energy and reduce cost. X-ray diffraction (XRD) analysis further revealed that a complex transition phase of silicates and aluminosilicates was accompanied by a conversion reaction of the silica-CaO and potassium feldspar-CaO systems, and that K2O capable of co-producing potash fertilizer escaped as a gas through the collection equipment.
TL;DR: Inorganic sulfur sources have been successfully used for introducing sulfur atom in order to replace thiols, which have the drawbacks of metal poisoning, unpleasant odour, and apt oxidation as mentioned in this paper.
Abstract: Inorganic sulfur sources have been successfully used for introducing sulfur atom in order to replace thiols, which have the drawbacks of metal poisoning, unpleasant odor, and apt oxidation. Efficie...
TL;DR: In this article, a simple and convenient synthetic strategy to construct β-iodovinyl sulfones through molecular iodine and DTBP (di-tert-butyl peroxide) was proposed.
Abstract: The present reaction provides a simple and convenient synthetic strategy to construct β-iodovinyl sulfones through molecular iodine and DTBP (di-tert-butyl peroxide) promoted difunctionalization of...
TL;DR: In this paper, an improved synthesis of N-sulfonylformamidine derivatives has been developed involving direct condensation of various sulfonamides and formamides in the presence of thionyl chloride using chlorofo...
Abstract: An improved synthesis of N-sulfonylformamidine derivatives has been developed involving direct condensation of various sulfonamides and formamides in the presence of thionyl chloride using chlorofo...
TL;DR: In this article, a series of 1,3-thiazolidine-4-ones 6a-n by cycloaddition reaction of N-aryl-N'-acyl thioureas 4a-k with acetylenic esters under microwave irradiation was described.
Abstract: This paper describes the synthesis of a novel series of 1,3-thiazolidine-4-ones 6a-n by cycloaddition reaction of N-aryl-N'-acyl thioureas 4a-k with acetylenic esters 5a-b under microwave irradiati...
TL;DR: In this paper, a novel chromono[2,3-e][1,2,4,3]triazaphosphepines 3−7, chromono [2,2-d][ 1,3,2]diazaphosphinine 8, chro-monyl α-hydrazinophosphonic acid 10, chromo[3, 2-d]azaphosphole 11 and diethyl N-chromony-...
Abstract: Novel chromono[2,3-e][1,2,4,3]triazaphosphepines 3−7, chromono[2,3-d][1,3,2]diazaphosphinine 8, chro-monyl α-hydrazinophosphonic acid 10, chromono[3,2-d][1,2]azaphosphole 11 and diethyl N-chromony-...
TL;DR: A total of 12 bis(acylthiourea) derivatives with different pharmacophores have been synthesized via nucleophilic substitution reaction of benzene-1,4-dicarbonyl isothiocyanate intermediate with aromatic amine bearing halogens at the ortho, meta and para positions as mentioned in this paper.
Abstract: A total of 12 bis(acylthiourea) derivatives with different pharmacophores have been synthesized via nucleophilic substitution reaction of benzene-1,4-dicarbonyl isothiocyanate intermediate with aromatic amine bearing halogens at the ortho, meta and para positions. The structures of the synthesised compounds were confirmed by CHN elemental analysis, FT-IR, ¹H NMR and ¹³C NMR spectroscopies. Antibacterial studies of the compounds via the Kirby Bauer disc diffusion method against Escherichia coli (E.coli) ATCC 25922 and Staphylococcus aureus (S. aureus) S48/81 demonstrated that bis(acylthiourea) N¹,N⁴-bis[(2-chlorophenyl)carbamothioyl]terephthalamide (4) and N¹,N⁴-bis[(2-bromophenyl)carbamothioyl]terephthalamide (7) bearing Cl and Br at the ortho position exhibited excellent activities against both bacteria strains compared to ampicillin standard.
TL;DR: In this paper, the cracking and reasons for aging of silicone rubber current transformer insulation sheath from a 500kV substation were investigated, including chemical characteristics including attenuated total reflectan...
Abstract: The cracking and reasons for aging of silicone rubber current transformer insulation sheath from a 500 kV substation were investigated. Chemical characteristics including attenuated total reflectan...
TL;DR: Some 1,3-dithiadiphosphetane 2,4-disulfides (X2P2S4, X: Fc, FcLR; X: CH3O, C6H4, LR) were allowed to react with alcohols to obtain dithiophosphonic acids (X(OR)PS2H) as discussed by the authors.
Abstract: Some 1,3-dithiadiphosphetane 2,4-disulfides (X2P2S4, X: Fc, FcLR; X: CH3O‒C6H4‒, LR) were allowed to react with alcohols to obtain dithiophosphonic acids (X(OR)PS2H). These were converted to the co...
TL;DR: The Bi(NO3)3.5H2O mediated synthesis of α-hydroxyphosphonates via phosphonylation of aldehydes is reported in this paper.
Abstract: The Bi(NO3)3.5H2O mediated synthesis of α-hydroxyphosphonates via phosphonylation of aldehydes is reported herein. Both conventional and microwave technology was efficiently applied to range of aro...
TL;DR: In this article, the platinum(II) compounds with asparagusic acid and derivatives as ligands were characterized using X-ray diffraction methods and the cytotoxic activi...
Abstract: This work presents platinum(II) compounds with asparagusic acid and derivatives as ligands. Examples of these derivatives were characterized using X-ray diffraction methods and the cytotoxic activi...
TL;DR: A series of novel N-pyridylpyrazolecarboxamides containing benzothiazole were designed and synthesized as discussed by the authors, and the target compounds were identified by 1H NMR,13C-NMR, IR, high-resolution mass spectrum (HR...
Abstract: A series of novel N-pyridylpyrazolecarboxamides containing benzothiazole were designed and synthesized. The target compounds were identified by 1H NMR,13C-NMR, IR, high-resolution mass spectrum (HR...
TL;DR: In this paper, a new procedure for the protection and deprotection process of various types of alcohols and phenols by HMDS in the presence of nano magnetic sulfated zirconia (Fe3O4@ZrO...
Abstract: In this work, we introduce a new procedure for the protection and deprotection process of various types of alcohols and phenols by HMDS in the presence of nano magnetic sulfated zirconia (Fe3O4@ZrO...