Showing papers in "Phosphorus Sulfur and Silicon and The Related Elements in 2018"
TL;DR: Flow cytometry analysis showed that compounds 4a-4p have a remarkable anticancer activity and a good selectivity towards C6 cell lines and that these compounds display antic cancer activity by inducing apoptosis.
Abstract: Sixteen new 2-(benzothiazol-2-ylthio)-N′-(3-substituted-4-(3,4-substitutedphenyl)thiazol-2(3H)-ylidene)acetohydrazide derivatives (4a-4p) were synthesized. The structures of the synthesized compoun...
27 citations
TL;DR: In this article, quantum chemistry calculations indicate that BN nanocage is a good candidate for selective complex formation with Li+ in the presence of different alkali metal ions, and it is shown that it can be used for selecting the most suitable complex with different metal ions.
Abstract: GRAPHICAL ABSTRACTQuantum chemistry calculations indicate that BN nanocage is a good candidate for selective complex formation with Li+ in the presence of different alkali metal ions.
18 citations
TL;DR: In this paper, the synthesis of 48 3-sulfonylamides containing a tricyclic thieno[2,3-d]pyrimidin-4(3H)-one moiety, and their influence on melanin synthesis in murine B16 cells were reported.
Abstract: Herein, we report the synthesis of 48 novel 3-sulfonylamides containing a tricyclic thieno[2,3-d]pyrimidin-4(3H)-one moiety, and their influence on melanin synthesis in murine B16 cells. All target sulfonylamides were synthesized through key intermediate 3-nitro-thieno[2,3-d]pyrimidin-4(3H)-ones using three types of ipso-nitration reactions. In this case, we converted the pyrido[1,2-a]- fragment of the thieno[2,3-d]pyrimidine moiety to pyrrolo[1,2-a]- and azepino[1,2-a]- side-rings in order to evaluate the bioactivities of the synthesized derivatives for a structure activity-relationships point of view. The obtained results suggest that some of the selected compounds revealed a promising influence on melanin synthesis in murine B16 cells and may serve as lead compounds for further drug discovery and development.
18 citations
TL;DR: In this article, a reusable nanocatalyst was synthesized by anchoring a nickel Schiff base complex onto Fe3O4@MCM-41 and characterization was accomplished with Fourier transform infr...
Abstract: A novel and reusable nanocatalyst was synthesized by anchoring a nickel Schiff base complex onto Fe3O4@MCM-41 (Fe3O4@MCM-41@Ni-P2C) and characterization was accomplished with Fourier transform infr...
17 citations
TL;DR: The reaction of thiophene-2-carbonyl isothiocyanate with phenylhydrazine gave 1-phenyl-5-(thien 2-yl)-1,2,4-triazole-3-thiol which was transformed by follow-up reactions into derivatives substitute as discussed by the authors.
Abstract: The reaction of thiophene-2-carbonyl isothiocyanate with phenylhydrazine gave 1-phenyl-5-(thien-2-yl)-1,2,4-triazole-3-thiol which was transformed by follow-up reactions into derivatives substitute...
16 citations
TL;DR: In this article, ZnFe2O4 nanoparticles were synthesized and used as recyclable magnetic catalyst in the solvent-free conversion of different epoxides to vicinal hydroxythiocyanates with NH4SCN at room temperature.
Abstract: GRAPHICAL ABSTRACT ABSTRACT ZnFe2O4 nanoparticles were synthesized and used as recyclable magnetic catalyst in the solvent-free conversion of different epoxides to vicinal hydroxythiocyanates with NH4SCN at room temperature. The reactions were carried out by grinding in a mortar with perfect regioselectivity within short times (2-25 min) and with high to excellent yields (75–95%). The nanocatalyst was separated easily using an external magnet and reused for four consecutive cycles without any noticeable loss of efficiency or magnetic property.
14 citations
TL;DR: A green protocol for the salkylation of 2-mercapto-1,3,4-oxadiazole by the reaction of 5-substituted 2-MERcapto with propargyl bromide in sodium bicarbonate in this paper.
Abstract: A new green protocol was developed for the S-alkylation of 2-mercapto-1,3,4-oxadiazole by the reaction of 5-substituted-2-mercapto-1,3,4-oxadiazole with propargyl bromide in sodium bicarbonate in w...
14 citations
TL;DR: The use of organophosphorus pesticides is undeniably beneficial in agriculture and veterinary medicine, but their excessive use can pollute the environment, as well as contaminate foodstuffs.
Abstract: The use of organophosphorus pesticides is undeniably beneficial in agriculture and veterinary medicine, but their excessive use can pollute the environment, as well as contaminate foodstuffs. The o...
13 citations
TL;DR: The peroxidation of linoleic acid in the presence of copper (II) ions alone and with butylhydroxytoluene (BHT), gallic acid (GA), a BHT/GA pair, 5-methoxyisatin-3-(N-4-chlorophenyl) thiosemica.
Abstract: The peroxidation of linoleic acid (LA) in the presence of copper (II) ions alone and with butylhydroxytoluene (BHT), gallic acid (GA), a BHT/GA pair, 5-methoxyisatin-3-(N-4-chlorophenyl) thiosemica...
13 citations
TL;DR: A series of novel 4]-(3-substituted)ureido]-N-(5methyl-1,3,4thiadiazol-2-yl) benzenesulfonamides and 4-[(3]-substitized)thioureido]-n-(5-methyl- 1, 3, 4thiadiadiazolate-2yl)benzenes sulfonamide were prepa...
Abstract: A series of novel 4-[(3-substituted)ureido]-N-(5-methyl-1,3,4-thiadiazol-2-yl) benzenesulfonamides and 4-[(3-substituted)thioureido]-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamides were prepa...
12 citations
TL;DR: In this article, the authors describe a semi-crystalline, intractable solid with poor mechanical properties and is not easy to melt and resists solid processing, which they call polymeric sulfur generated from thermal ROP.
Abstract: Polymeric sulfur generated from thermal ROP forms a semi crystalline, intractable solid with poor mechanical properties and is not easy to melt and resists solid processing. Stabilization o...
TL;DR: In this paper, a dicyclohexylcarbodiimide-promoted protocol for the selective and controllable esterification of P(O)OH compounds using O-nucleophiles (alcohols and phenols) as efficient ester.
Abstract: A novel and efficient dicyclohexylcarbodiimide-promoted protocol for the selective and controllable esterification of P(O)OH compounds using O-nucleophiles (alcohols and phenols) as efficient ester...
TL;DR: The development of efficient antimicrobial metaloxide nanoparticles (MONPs) is important to advance in the biomedical and in the industrial fields as mentioned in this paper, and ZnO-CuO nanoparticles with improved antibact...
Abstract: Development of efficient antimicrobial metal-oxide nanoparticles (MONPs) is important to advance in the biomedical and in the industrial fields. Herein, ZnO-CuO nanoparticles with improved antibact...
TL;DR: In this paper, a new approach was developed to prevent the formation of magnesium silicide (Mg2Si) by using alumina as a consumer of gaseous magnesium, and highly pure silicon was produced by firstly purifying the silica regent by acid-leaching.
Abstract: Magnesiothermic reduction of silica is a powerful method for producing silicon owing to its simplicity, low reduction temperature and low production cost. However, the inevitable formation of magnesium silicide (Mg2Si) limits the use of this method. A new approach was developed in this research to prevent the formation of Mg2Si by using alumina as a consumer of gaseous magnesium. Utilizing this approach, highly pure silicon was produced by firstly purifying the silica regent by acid-leaching. It was then subjected to magnesiothermic reduction regimes in order to optimize the power input and molar Mg/SiO2 ratio to minimize Mg2Si production. Silicon products were analyzed by X-ray powder diffraction (XRD) and quantitative Rietveld refinement. Optimum electrical power and molar ratio were found to be 3.75 kW and 2.25:1, respectively. The silicon product was examined by glow discharge mass spectrometry which indicated that its purity was 99.96%, with 0.10 ppm of B and 0.15 ppm of P, making it an attra...
TL;DR: In this paper, 2-sulfido-2,3-dihydro-4H-chromeno[2, 3-d][1, 3,2]diazaphosphinines were obtained in a simple one-pot procedure via treatment of 2-imino-2H,chromene-3-carboxamide with various phosphorus sulfides.
Abstract: Novel 2-sulfido-2,3-dihydro-4H-chromeno[2,3-d][1,3,2]diazaphosphinines are obtained in a simple one-pot procedure via treatment of 2-imino-2H-chromene-3-carboxamide with various phosphorus sulfides...
TL;DR: An efficient and eco-friendly protocol for the preparation of 2-amino-3-phenylsulfonyl-4H-chromenes employing a three component, one-pot condensation reaction between aromatic aldehydes, phenylsulp...
Abstract: An efficient and eco-friendly protocol for the preparation of 2-amino-3-phenylsulfonyl-4H-chromenes employing a three component, one-pot condensation reaction between aromatic aldehydes, phenylsulp...
TL;DR: A series of chromene derivatives (5a-f) were prepared by multistep synthesis process using 2-[3-phenyl prop-2-ene nitrile] 1,3-benzothiazole and dimedone using piperidine as catalyst in ethanol as discussed by the authors.
Abstract: A series of chromene derivatives (5a–f) were prepared by multistep synthesis process using 2-[3-phenyl prop-2-ene nitrile] 1,3-benzothiazole and dimedone using piperidine as catalyst in ethanol. Th...
TL;DR: In this article, the synthesis of five N,N-substituted thiocarbamides, namely N-(naphthyl)-N″-(pentoxycarbonyl) thIocarbamide (H2L1), N-(2-Chloro-4-nitrophenyl)-n″(pentoxy carbonyl)-ninth-form of thIOCarbamide(H 2L2), H2L2, N-( 2-metho...
Abstract: The synthesis of five N,N″-substituted thiocarbamides, namely N-(naphthyl)-N″-(pentoxycarbonyl) thiocarbamide (H2L1), N-(2-Chloro-4-nitrophenyl)-N″-(pentoxycarbonyl) thiocarbamide(H2L2), N-(2-metho...
TL;DR: In this paper, ultrasonic irradiation has been applied to the reaction mixtures containing amine, aromatic or heteroaromatic aldehydes and tarsic acid.
Abstract: To obtain a rapid, efficient synthesis of some new α-aminophosphonates, ultrasonic irradiation has been applied to the reaction mixtures containing amine, aromatic or heteroaromatic aldehydes and t...
TL;DR: Inorganic-organic hybrid cyclomatrix type polyphosphazene microspheres (poly[cyclotriphosphaspazene-co-(4,4′-diaminodiphenylmethane)]) (HDMS) and poly [cyclotetraphosphazenes-co-4, 4, 4′-diminodiph...
Abstract: Inorganic–organic hybrid cyclomatrix type polyphosphazene microspheres (poly[cyclotriphosphazene-co-(4,4′-diaminodiphenylmethane)]) (HDMS) and poly[cyclotetraphosphazene-co-4,4′-diaminodiph...
TL;DR: Tunisian industrial phosphoric acid H3PO4 was supported on silica gel SiO2 (SIPA) to catalyze the hydrolysis reaction of aqueous alkaline sodium borohydride (NaBH4) as discussed by the authors.
Abstract: Tunisian industrial phosphoric acid H3PO4 was supported on silica gel SiO2 (SIPA) to catalyze the hydrolysis reaction of aqueous alkaline sodium borohydride (NaBH4). The SiO2 was produced from puri...
TL;DR: In this article, a metal-free procedure for the synthesis of (E)-vinyl sulfones has been developed through the coupling of β-nitrostyrenes with sodium sulfinates under microwave irradiation.
Abstract: A practical metal-free procedure for the synthesis of (E)-vinyl sulfones has been developed through the coupling of β-nitrostyrenes with sodium sulfinates under microwave irradiation. This methodol...
TL;DR: A series of new phosphoramidates and phosphonates were synthesized in single step by reacting diethyl phosphorochloridate with various bioactive amines as discussed by the authors.
Abstract: A series of new phosphoramidates and phosphonates were synthesized in single step by reacting diethyl phosphorochloridate with various bioactive amines. The newly synthesized compounds 3a-j were te...
TL;DR: The molecule (−)-(S)-1-[2-(benzenesulfonamido)-3-phenylpropanoyl]-4-[(4-methyl)phenyl] thiosemicarbazide was synthesized and its structure analyzed by X-ray diffraction to understand its geometry as discussed by the authors.
Abstract: The molecule (−)-(S)-1-[2-(benzenesulfonamido)-3-phenylpropanoyl]-4-[(4-methyl)phenyl] thiosemicarbazide was synthesized and its structure analyzed by X-ray diffraction to understand its geometry, ...
TL;DR: The synthesis of some novel chromonyl and pyrazolyl α-aminophosphonates containing a quinazolinone ring was carried out by applying Pudovik and Kabachnik-Fields reactions under solvent-and catalyst-free conditions as mentioned in this paper.
Abstract: The synthesis of some novel chromonyl and pyrazolyl α-aminophosphonates containing a quinazolinone ring was carried out by applying Pudovik and Kabachnik-Fields reactions under solvent- and catalyst-free conditions The anticancer activities of these compounds were evaluated against five cancer cell lines 3-{[(3-Phenyl/1,3-diphenyl-1H-pyrazol-4-yl)methylidene]amino}-2-phenyl-quinazolin-4(3H)-ones (3d,e) and diethyl {[3-phenyl/1,3-diphenyl-1H-pyrazol-4-yl][(4-oxo-2-phenyl-quinazolin-3(4H) yl)amino] methyl}phosphonates (4d,e) displayed the potent anticancer activities against HCT116, MCF-7 and HepG2 cell lines in comparison with the standard drug
TL;DR: A series of nickel (II) complexes bearing silicon bridged diphosphines ligands (PNSiP) have been synthesized and characterized in this paper, and all nickel precatalysts, activated with ethylaluminum dichloride (EtA...
Abstract: A series of nickel (II) complexes bearing silicon bridged diphosphines ligands (PNSiP) have been synthesized and characterized. All nickel precatalysts, activated with ethylaluminum dichloride (EtA...
TL;DR: In this article, the synthesis of 2-amino-4H-chromen-4-ylphosphonate derivatives has been accomplished by the one-pot three-component reaction of salicylaldehyde, malononitrile/ethylcyanoacetate and dialkyl phosphites.
Abstract: Synthesis of 2-amino-4H-chromen-4-ylphosphonate derivatives has been accomplished by the one-pot three-component reaction of salicylaldehyde, malononitrile/ethylcyanoacetate and dialkyl phosphites ...
TL;DR: In this paper, a mixture of 4-methyl-4H-1,2,4-triazole-3-thiol (Hmtrzt) and ethylenediamine (en) with K2PtCl4 in CH3OH/H2O (2:1) was synthesized from the reaction of a mixture.
Abstract: The complex [Pt2(μ-mtrzt)4(mtrzt)2] (1) was synthesized from the reaction of a mixture of 4-methyl-4H-1,2,4-triazole-3-thiol (Hmtrzt) and ethylenediamine (en) with K2PtCl4 in CH3OH/H2O (2:1) as sol...
TL;DR: A convenient NaBr mediated procedure is developed for the preparation of 3-selanylindoles from indoles and diselenides with high regioselectivity and in moderate to good yields.
Abstract: A convenient NaBr mediated procedure is developed for the preparation of 3-selanylindoles from indoles and diselenides. In this protocol, NaBr is first oxidized by mCPBA into molecular bromine, whi...
TL;DR: A series of polyfunctionalized anthraquinone-hydrazones have been prepared using azo-coupling reaction between Anthrasquone-based triazenes and methylene active compounds in acetic acid without a c....
Abstract: A series of polyfunctionalized anthraquinonehydrazones have been prepared using azo-coupling reaction between anthraquinone-based triazenes and methylene active compounds in acetic acid without a c...