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Showing papers in "Phytochemistry in 2000"


Journal ArticleDOI
TL;DR: Some of the recent advances in flavonoid research are reviewed and the role of anthocyanins and flavones in providing stable blue flower colours in the angiosperms is outlined.

3,465 citations


Journal ArticleDOI
TL;DR: Ethyl acetate extracts of Sephadex LH20-purified proanthocyanidins of American cranberry exhibited potent biological activity by inhibiting adherence of uropathogenic isolates of P-fimbriated Escherichia coli bacteria to cellular surfaces containing alpha-Gal(1-->4)beta-Gal receptor sequences similar to those on epithelial cells in the urinary tract.

436 citations


Journal ArticleDOI
TL;DR: During fruit ripening, the mean degree of polymerization of extracted procyanidins is unchanged when analyzed intact by HPLC, but decreases by thiolytic degradation, indicating that cultural practices can be used to influence composition.

366 citations


Journal ArticleDOI
TL;DR: The current state of knowledge of the properties of lycopene, its possible role in human health and areas for future research are summarized.

327 citations


Journal ArticleDOI
TL;DR: From the evidence presented, it can be inferred that micromolecules which neutralize the action of snake venoms mechanistically replace endogenous antitoxic serum proteins with venom neutralizing capacity such as produced by some animals.

325 citations


Journal ArticleDOI
TL;DR: The profound developments in natural products drug discovery in the past few years are discussed, and the importance of a global approach to biodiversity and drug discovery involving natural products for the early part of the 21st century is presented.

324 citations


Journal ArticleDOI
TL;DR: A comprehensive survey of the extensive literature relevant to the evolution, physiology, biochemistry, regulation, and genetic engineering applications of plant aromatic L-amino acid decarboxylases (AADCs) is presented.

271 citations


Journal ArticleDOI
TL;DR: Three novel phenolic glycosides cis-p-coumaric acid, luteolin glucuronides and vicenin-2 were identified as new sage constituents.

241 citations


Journal ArticleDOI
TL;DR: This review illustrates the distribution of tropane alkaloids within the families Solanaceae, Erythroxylaceae, Proteaceae, Euphorbiaceae, Rhizophoraceae, Convolvulaceae and Cruciferae.

231 citations


Journal ArticleDOI
TL;DR: A review of mass spectrometric techniques applied to the identification and structural studies of flavonoid glycosides is presented.

224 citations


Journal ArticleDOI
TL;DR: The isolation and characterization of several representatives including two hitherto unreported amides were performed by chromatographic techniques and by analysis of spectroscopic data.

Journal ArticleDOI
TL;DR: Enantiomeric mixtures of sesquiterpenes of the cadinane, eudesmane (selinane), oppositane, axane, isodaucane, and bourbonane group as well as isogermacrene D were identified as main products and made available as reference compounds for structure investigations and stereochemical assignments of plant constituents.

Journal ArticleDOI
TL;DR: It is concluded that the combination of a commercial antioxidant and biocide is synergistic, which implies that extractives may protect wood by more than simply being fungicidal.

Journal ArticleDOI
TL;DR: A new 96-well microbioassay procedure for fast and easy evaluation of antifungal activity was used to compare these compounds with commercial fungicide standards and some structure-activity conclusions are presented.

Journal ArticleDOI
TL;DR: Pumpkin (Cucurbita pepo) seeds are used locally in Eritrea to treat tapeworm and contains an appreciable amount of unsaturated fatty acids and is found to be a rich source of linoleic acid.

Journal ArticleDOI
TL;DR: This work reviews work reporting the chemical structures, synthesis, biosynthesis and metabolism of cruciferous phytoalexins, as well as their biological activity towards different microorganisms.

Journal ArticleDOI
TL;DR: It is found that the phosphorylation of hexose by hexokinase, but not its transport, has to be taken into account for the sucrose signal transduction leading to anthocyanin accumulation.

Journal ArticleDOI
TL;DR: The results of this study define for the first time the substantial effect AVIs have on flower colour, and provide insights into their nature and their specificity as vacuolar anthocyanin traps.

Journal ArticleDOI
TL;DR: The influence of culture age and nitrogen concentration on the distribution of fatty acids among the different acyl lipid classes has been studied in continuous cultures of the microalga Phaeodactylum tricornutum.

Journal ArticleDOI
TL;DR: The glycosylation sites of GAGP were inferred based on the Hyp contiguity hypothesis which predicts arabinosides on contiguous Hyp residues and arabinogalactan polysaccharides on clustered non-contiguous Hyp residues, and this rigidifies the glycoprotein, enhances the overall symmetry of the glycopeptide motif, and may explain some of the remarkable properties of gum arabic.

Journal ArticleDOI
TL;DR: The production of OH* from O2 by HRP in the presence of NADH or DHF was confirmed by EPR spectroscopy using 5,5-dimethyl-1-pyrroline-N-oxide as a spin trap, confirming the involvement OH* as the causative agent for macromolecule cleavage.

Journal ArticleDOI
TL;DR: The flavonoid dichotomy indicates that there are at least two evolutionary lineages within H. lupulus (European and Japanese American), which is in agreement with morphological, molecular, and phytogeographical evidence.

Journal ArticleDOI
TL;DR: The methanol extract of the dried roots of Ferula sumbul afforded two furanocoumarin esters and some of the isolated compounds showed anti-HIV activity and very weak inhibition of cytokine release.

Journal ArticleDOI
TL;DR: The role of NO in plant development and in plant interactions with microorganisms, involving an interplay with other molecules, like ethylene or reactive oxygen species, is discussed in this paper.

Journal ArticleDOI
TL;DR: The neutral lipid profiles of nine species of thin trilaminar outer wall (TLS)-containing freshwater and marine microalgae from the class of Chlorophyceae were studied with emphasis on the relationship between the lipid content and the occurrence of insoluble non-hydrolysable biopolymer.

Journal ArticleDOI
TL;DR: Comparison of the compositions of oleoresins from Copaifera guianensis Desf.

Journal ArticleDOI
TL;DR: The 13C-NMR spectra showed that the polymers consisted of only gallocatechin and epigallocatechin monomeric units with the latter being about twice as abundant in the extenders but only slightly more than that in the terminating units.

Journal ArticleDOI
TL;DR: In this article, the variation of all 1,4-benzoxazin-3-one derivatives content detectable in maize with plant age in roots and aerial parts was reported.

Journal ArticleDOI
TL;DR: An unusual biflavonoid named licoagrodin was isolated from the hairy root cultures of Glycyrrhiza glabra along with four known isoflavone glycosides, two flavone C-glycoside, and three other glycoside structures, which were elucidated on the basis of spectroscopic evidence.

Journal ArticleDOI
TL;DR: Activity-stained SDS polyacrylamide gel electrophoresis (PAGE) gels and western blots probed with PPO antibodies suggested the existence of a 67 kDa PPO which is susceptible to proteolytic cleavage that generates a 45 kDa active form.