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Showing papers in "Phytochemistry in 2021"


Journal ArticleDOI
TL;DR: Assumptions of an extended range of co- and post-transcriptional processes to the regulation of unexplored PPO expression are proposed and the identification of endogenous PPO substrates and downstream targets of PPO action will be useful for elucidating PPO defensive roles.

51 citations


Journal ArticleDOI
TL;DR: In this article, a review focusing on recent literature covering synthetic pathways of flavor compounds and scaffold hopping based on the α-pinene core domaine, as well as the (enantioselective) activities of αpinene is presented.

47 citations


Journal ArticleDOI
TL;DR: Emodin (1,3,8-trihydroxy-6-methyl-anthraquinone) is a natural anthrasquinone derivative that is present in numerous globally renowned herbal medicines and has been recognized as a protein tyrosine kinase inhibitor and an anticancer drug, active against various tumour cells, including lung, breast, liver, and ovarian cancer cells.

38 citations


Journal ArticleDOI
TL;DR: Wang et al. as mentioned in this paper summarized all the isolated diterpenoids from the genus Euphorbia according to their skeleton types, classified all these dinerpenoids into 26 normal classes and 37 novel skeleton types and summarized their biological activity.

37 citations


Journal ArticleDOI
TL;DR: In this paper, the potential of Apiaceae species as suitable sources of bioactive phytochemicals with great relevance within the frame of plant-based pesticides R&D, and will discuss their applicability in real-world scenarios considering the recent developments regarding the design of stable formulations incorporating apiaceae bioactive products.

33 citations


Journal ArticleDOI
TL;DR: This article is a critical account of discovery of known as well as undescribed structural types and pharmacological activities reported in the course of 2016-2020 of Isocoumarins and dihydroisocou marins.

30 citations


Journal ArticleDOI
TL;DR: Prenylated flavonoids, a unique class of compounds which combine a flavonoid skeleton and a lipophilic prenyl side-chain, possess great potential biological activities including cytotoxicity, anti-inflammation, antiAlzheimer and enzyme inhibition.

27 citations


Journal ArticleDOI
Hasan Haskirli1, Oguzhan Yilmaz1, Rengin Ozgur1, Baris Uzilday1, Ismail Turkan1 
TL;DR: Melatonin treatment did not have any effect on glutathione biosynthesis and catabolism genes, however, expression of alternative oxidase 1a (AOX1a) and AOX1d were lower in UV-B + melatonin treated plants when compared to onlyUV-B treated plants, which indicates lower oxidative load in mitochondria.

23 citations


Journal ArticleDOI
TL;DR: In this paper, the authors describe the mechanisms and kinetics of HO, NO, HOO, and NO2 scavenging activities of daphnetin in physiological environments using quantum chemistry calculations.

22 citations


Journal ArticleDOI
TL;DR: 15 compounds were purified to yield enantiomers (a, b) via chiral-phase HPLC, and their configurations were determined by optical rotation values and the comparison of the experimental and calculated electronic circular dichroism (ECD) curves.

20 citations


Journal ArticleDOI
TL;DR: Among the several subfamilies of ABC transporters, the ABC-G subfamily is very significant as discussed by the authors, which houses the highest number of transporter with mostly half-size transporter (called WBC) and fewer full-size Transporters (called PDR) in Arabidopsis thaliana.

Journal ArticleDOI
TL;DR: A review of the phytochemistry and pharmacology of medicinal Iranian Salvia species in order to describe their therapeutic potential for a range of diseases is presented in this paper, including carminatives, analgesics, digestive aids, antiseptics, sedative, anxiolytic, hypnotic, pain reduction and antidiabetic.

Journal ArticleDOI
TL;DR: In this paper, the phytochemical assessment of Cinnamomum migao H. W. Li fruits illustrated the isolation and identification of ten undescribed guaiane-type sesquiterpenoids "miganoids A−J″ and one undiscribed sesiquiterpene "7(S)-(hydroxypropanyl)-3-methyl-2-(4-oxopentyl) cyclohex-2-en-1-one”.

Journal ArticleDOI
TL;DR: In this paper, the authors summarize the current knowledge addressing the anti-cancer effects of dietary tannins and their underlying molecular mechanisms, and discuss the absorption, distribution, metabolism, excretion, and toxicity properties of tannin, clinical trial results as well as their perspective on future research with tANNins.

Journal ArticleDOI
TL;DR: Twelve undescribed 2-(2-phenylethyl)chromone derivatives, including one pair of enantiomers, together with eleven known ones, were isolated from the EtOAc extract of agarwood originating from Aquilaria filaria and revealed the potential of 2-( 2-phenylesthyl]chromones as α-glucosidase inhibitors.

Journal ArticleDOI
TL;DR: Findings indicate that ACh-induced salt tolerance in N. benthamiana seedlings is mediated by the inhibition of antioxidant enzymes, activation of cell wall biosynthesis, and hormone signalling pathways.

Journal ArticleDOI
TL;DR: The profile of glycolipid molecules, which form SD thylakoid membranes, seems to be species-specific and does not depend on the host's taxonomic position, in contrast, the betaine lipid molecular species profile of diacylglyceryl-3-O-carboxyhydroxymethylcholine (DGCC), which forms SD cell membranes, can be influenced by the host.

Journal ArticleDOI
TL;DR: In this paper, eight undescribed diterpenoids, euphorfinoids E-L, together with twelve known analogues, were isolated from the roots of wild Euphorbia fischeriana.

Journal ArticleDOI
TL;DR: Results support the concept of utilizing Aglaia species as a potential source for the production of biologically active compounds, and flavagline (rocaglamide) derivatives have been confirmed to exhibit exceptional cytotoxicity, and are, thus, considered lead compounds for further development.

Journal ArticleDOI
TL;DR: In this article, 13 undescribed dammarane triterpenoid saponins (cypaliurusides A and M) were isolated from Cyclocarya paliurus.

Journal ArticleDOI
TL;DR: In this article, a non-targeted metabolomics approach for the discrimination between fresh ginger rhizome samples collected from four different producing countries, i.e., China, India, Pakistan, and Peru, is presented.

Journal ArticleDOI
TL;DR: In this article, the kinetics and exact mechanism of the peroxyl radical scavenging activity of CARS in the gas phase and under physiological conditions were investigated in aqueous solution.

Journal ArticleDOI
TL;DR: An overview of the known chemical diversity of taxanes, with an emphasis on the functionalization of diterpene scaffolds, is provided in this paper, where the implications of the occurrence of chemically diverse taxane metabolites for unraveling Taxol biosynthesis and enabling pathway engineering are discussed as well.

Journal ArticleDOI
TL;DR: In this article, a plausible biosynthetic pathway for pyrrolyl 4-quinolone alkaloids is proposed, which shares a 6/6/5/5 tetracyclic system incorporating a rare tetrahydro-pyrrolynl moiety.

Journal ArticleDOI
TL;DR: In this paper, transcriptome sequencing efforts were made to elucidate isosteroidal alkaloids biosynthesis by creating first organ-specific genomic resource using bulb, stem, and leaf tissues derived from natural populations of Indian Himalayan region.

Journal ArticleDOI
Rong-Wei Kou1, Rui Han1, Yu-Qi Gao1, Ding Li1, Xia Yin1, Jin-Ming Gao1 
TL;DR: Results indicated that the potential anti-inflammatory effects of inonotusols I and L in microglial BV-2 cells may be imparted through suppression of iNOS, and may support the use of I. obliquus for food and medicinal application.

Journal ArticleDOI
TL;DR: In this article, the planar structures and relative configurations of globosumin and globosumone were determined by high-resolution ESI-MS and NMR data, and the absolute configurations of these two metabolites are determined by electronic circular dichroism (ECD) combined with time-dependent density functional theory (TDDFT)-based quantum-chemical calculations.

Journal ArticleDOI
TL;DR: In this article, a comparative transcriptome sequencing of the bulb (in vivo), callus, and regenerated plantlets (in vitro) resulted in more than 150 million high-quality paired-end clean reads that assembled into final 31,428 transcripts.

Journal ArticleDOI
TL;DR: In this paper, the phytochemical and biological properties of natural bisabolane-type sesquiterpenoids (356 compounds in total) isolated between 1985 and 2020 from 24 families, primarily Compositae, Zingiberaceae, Aspergillaceae, Halichondriidae, and Aplysiidae were reviewed.

Journal ArticleDOI
TL;DR: The results reveal a possible link between rapidly induced terpenoid metabolism and the autoimmunity underlying anthracnose resistance in a wild strawberry species.