Showing papers in "Phytomedicine in 2005"

TL;DR: A comprehensive review of the literature to summarize the pharmacological and clinical effects of this popular plant material found ginger exerts in vitro antioxidative, antitumorigenic and immunomodulatory effects and is an effective antimicrobial and antiviral agent.

TL;DR: A review of the literature on plant extracts and chemically defined molecules of natural origin showing antileishmanial activity and some aspects of recent antileishesmanial-activity-directed research on natural products are discussed.

TL;DR: Investigation must be continued in the recently observed actions of Bacopa monniera to evidence any side effects and possible interactions between this herbal medicine and synthetic drugs.

TL;DR: The results confirm the importance of phenolics for propolis antibacterial activity, and the significance of P. nigra L. as a propolis source, which provides the hive with the best defense against microorganisms.

TL;DR: Fractions and subfractions of turmeric extracts collected via preparative HPLC had differing biological activity, indicating interaction of the compounds within the fraction to produce an anti-inflammatory effect.

TL;DR: Findings suggested that alpha-mangostin alone or in combination with GM against VRE and in conjunction with VCM against MRSA might be useful in controlling V RE and MRSA infections.

TL;DR: Oral administration of the aqueous extracts successfully obliterated salmonella infection in Balb/C mice as revealed by increased survival rate as well as less bacterial load in various vital organs of the treated animals.

TL;DR: Results showed that the DFE possessed marked antioxidant activity in both biological and chemical models, and the efficacy of DFE in inhibiting both reactive oxygen species and nitric oxide were attributed to its phenolic content.

TL;DR: Caffeic acid (CA), its methylated derivates ferulic Acid (FA) and isoferulic acid (IFA) and the hydrogenation products dihydrocaffeic Acid (DHCA) and dihydroferulic acid(DHFA) were identified as metabolites derived from caffeoylquinic acids.

TL;DR: The present results indicate that the water extract of U. longissima has a protective effect in indomethacin-induced ulcers, which can be attributed to its antioxidant potential.

TL;DR: Aloe is the only known supplement to increase the absorption of both of these vitamins and should be considered as a complement to them.

TL;DR: Results suggest that both CHE and coumarin may influence the secretion control mediated by the parasympathetic system.

TL;DR: The results suggested that E. brevicornum Maxim.

TL;DR: The aqueous extract of Abutilon indicum exhibited significant hepatoprotective activity by reducing carbon tetrachloride- and paracetamol-induced change in bio-chemical parameters that was evident by enzymatic examination.

TL;DR: The 60-min fraction of Myrica gale L. (Myricaceae) extracts showed higher anticancer activity against both tumor cell lines with an IC50 value of 88 +/- 1 microg/ml, which could be due to sesquiterpene enrichment.

TL;DR: It is confirmed that induction of aggregation of human platelets by PAF requires at least 200 times higher concentration when compared to rabbit cells, which raises serious doubts that the PAF antagonistic effect of ginkgolides could be responsible for hemorrhage in patients taking EGb 761.

TL;DR: The results demonstrated that the patients treated with Liv-52 for 6 months had significantly better child-pugh score, decreased ascites, decreased serum ALT and AST, and in placebo administered patients all the clinical parameters recorded at beginning of the study were not significantly different than after 6 months.

TL;DR: The principal pharmacodynamic effect of peppermint oil relevant to the gastrointestinal tract is a dose-related antispasmodic effect on the smooth musculature due to the interference of menthol with the movement of calcium across the cell membrane.

TL;DR: It can be concluded that Pepticare possesses anti-ulcer activity, which can be attributed to its anti-oxidant mechanism of action.

TL;DR: The total alkaloid and ethanol extracts of nine different plants from Brazilian families which produce isoquinoline alkaloids were tested, to determine their in vitro antiparasitic effect against L. chagasi and T. cruzi parasites.

TL;DR: Hderasaponin-C, -E and -F, may exert their anti-inflammatory effects by blocking bradykinin or other inflammation mediators, and is likely that sugars at C3 position and Rha7-Glcl-6Glc moiety at C28 position are essential for the acute anti- inflammation effect.

TL;DR: Results indicated that administration of P. amarus can significantly reduce the toxic side effects of CTX and is not interfering with the antitumor efficiency of CTQ, thereby decreasing the effect of toxic metabolites of CTZ on the cells.

TL;DR: The effects of corn silk aqueous extract on the urinary excretion of water, Na+, K+ and uric acid excretions, and glomerular and proximal tubular function and Na+ tubular handling were studied.

TL;DR: Bioassay-guided fractionation of the ethanol extract led to identify four triterpenic acids of oleanane series, four pimarane and one iso-pimarane diterpenes, as well as the phenolic monoterpene carvacrol and its glucoside, which revealed an anti-inflammatory activity comparable to that of indomethacin.

TL;DR: Forty-nine methanol extracts of 37 species of Malaysian medicinal plants were investigated for their inhibitory effects on platelet-activating factor (PAF) binding to rabbit platelets, using 3H-PAF as a ligand to find new PAF antagonists.

TL;DR: The results confirm the antiinflammatory properties of A. conyzoides, with no apparent hepatotoxicity, as well as the absence or presence of toxicity by prolonged use of HAE.

TL;DR: The findings suggest that the probable mechanism of nephroprotection by C. auriculata against cisplatin- and gentamicin-induced renal injury could be due to its antioxidant and free-radical-scavenging property.

TL;DR: Taking into account the currently available drug treatments for IBS PO may be the drug of first choice in IBS patients with non-serious constipation or diarrhea to alleviate general symptoms and to improve quality of life.

TL;DR: The results suggest that EtOH and DCM extracts obtained from M. americana possess excellent antisecretory and/or gastrotective effect in all gastric ulcer models, and suggest that the antiulcerogenic compound(s) present in M. Americana may be clustered in the apolar fraction.

TL;DR: Optimal pH triggered enteric coated formulations start releasing PO in the small intestine extending release over 10-12 h thus providing PO to the target organ in irritable bowel syndrome, i.e. the colon.