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Showing papers in "Progress in Cardiovascular Diseases in 1972"



Journal ArticleDOI
TL;DR: Fatty acid uptake was accelerated by increased cardiac work due to an acceleration of carnitine-palmityl CoA transferase and reduced levels of tissue FFA, suggesting that Regulation of fatty acid utilization by the heart is poorly understood.

492 citations


Journal ArticleDOI
TL;DR: All indications are that the use of ultrasound to examine the cardiovascular system, and especially the heart, should expand markedly in the near future and play an increasingly valuable role in clinical cardiology.

146 citations


Journal ArticleDOI
TL;DR: Experimental work on the effects of induced cardiac anomalies on the development of the fetal circulation should be encouraged to increase understanding of the relationships between congenital heart disease and the cardiovascular adaptation following birth.

76 citations


Journal ArticleDOI
TL;DR: A surgical technique for correction of cardiac anomalies in infancy, which utilizes surface cooling to low temperatures, intracardiac repair during a 1-hr circulatory arrest period, and rapid rewarming by total body perfusion is described.

75 citations



Journal ArticleDOI
TL;DR: Experimental work aimed at producing cardiac anomalies has little or no value for the study of the pathogenesis of such anomalies, and the effect of various teratogens appears to be rather nonspecific and the malformations produced by any one agent are not consistently all of the same type.

56 citations





Journal ArticleDOI
TL;DR: The authors have found it convenient to modify Goodwin’s definition of cardiomyopathy because of the different spectrum of myocardial disease in children when compared with adults.




Journal ArticleDOI
TL;DR: The incidence, the natural history, and the prognosis of conduction disturbances in association with acute myocardial infarction have been described, and a rational approach to their treatment has been presented in relation to the abnormal anatomy and physiology of the lesions.



Journal ArticleDOI
TL;DR: Hemodynamic investigations of the infant and child with congenital heart disease encompasses accurate determinations of blood flow, pressure, ventricular and atrial volumes, and cardiac muscle function and can add a valuable dimension to the overall evaluation of the patient with heart disease.

Journal ArticleDOI
TL;DR: The most significant factors permitting this low mortality rate include the immediate increase in flow of blood to ischemic myocardium, the technical advances in microsurgery which permit effective anastomoses to arteries as small as 1.0 mm internal diameter, and the increasing safety of all operative procedures performed with cardiopulmonary bypass.



Journal ArticleDOI
TL;DR: An understanding of the mechanism of control of heart rate, the importance of normal adjustments, and the consequence of disturbance of these adjustments are of critical importance not only to the cardiovascular physiologist but to the physician called upon to deal with patients with disturbances of impulse formation and a variety of other cardiac disorders is aid in providing such an understanding.


Journal ArticleDOI
TL;DR: In certain lesions, the Electrocardiographic-hemodynamic correlations are close enough to allow the Frank electrocardiogram to be of significant help in the clinical management of children with congenital heart disease.

Journal ArticleDOI
TL;DR: An overall approach to perioperative care of the infant from the time that a congenital heart defect is suspected until the late post-surgical recovery period is presented.


Journal ArticleDOI
TL;DR: The most useful maneuver that the clinician can carry out is provoking an attack of symptoms under direct observation, and can then study the accompanying subjective, auscultatory, and electrocardiographic phenomena as well as the effectiveness of specific modalities of pain relief.