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JournalISSN: 0273-2300

Regulatory Toxicology and Pharmacology 

Elsevier BV
About: Regulatory Toxicology and Pharmacology is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Population & Toxicity. It has an ISSN identifier of 0273-2300. Over the lifetime, 4632 publications have been published receiving 138997 citations. The journal is also known as: RTP & R.T.P..


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Journal ArticleDOI
TL;DR: This paper evaluates several approaches to allow the relative potency of the different PAHs to be considered in a site-specific risk assessment and presents a modified version that it feels more accurately reflects the state of knowledge on the Relative potency of these compounds.

2,339 citations

Journal ArticleDOI
TL;DR: The survey results support the value of in vivo toxicology studies to predict for many significant HTs associated with pharmaceuticals and have helped to identify HT categories that may benefit from improved methods.

1,699 citations

Journal ArticleDOI
TL;DR: A newly developed probabilistic model, the Creme RIFM model, is used to estimate aggregate exposure to fragrance ingredients using the example of 2-phenylethanol (PEA) to demonstrate the utility of the model in determining systemic and dermal exposure to fragrances from individual products, and aggregate exposure.

1,108 citations

Journal ArticleDOI
TL;DR: The data and modelling methods presented show potential as a means of performing ingredient safety assessments for personal care and cosmetics products, and the robustness and ability to estimate aggregate consumer product exposure are presented.

1,057 citations

Journal ArticleDOI
TL;DR: The Creme RIFM model offers a very comprehensive and powerful tool for estimating aggregate exposure to fragrance ingredients, suggesting that deterministic models overestimate exposure by 11.5–25 fold.

1,050 citations

Performance
Metrics
No. of papers from the Journal in previous years
YearPapers
202393
2022177
2021190
2020211
2019233
2018254