Research and reviews: journal of medical and health sciences 

About: Research and reviews: journal of medical and health sciences is an academic journal. The journal publishes majorly in the area(s): Population & Cancer. It has an ISSN identifier of 2319-9865. Over the lifetime, 481 publications have been published receiving 1172 citations.

Insulin Resistance and Type 2 Diabetes

Abstract: As weight problems and diabetes attain epidemic proportions in the developed global, the role of insulin resistance and its outcomes are gaining prominence. Understanding the role of insulin in extensive-ranging physiological strategies and the effects on its synthesis and secretion, alongside its actions from the molecular to the complete body degree, have sizeable implications for a lot chronic disease visible in Westernised populations nowadays. This overview provides a top level view of insulin, its history, shape, synthesis, secretion, actions and interactions observed with the aid of a discussion of insulin resistance and its associated clinical manifestations. Specific regions of attention include the actions of insulin and manifestations of insulin resistance in precise organs and tissues, physiological, environmental and pharmacological impacts on insulin action and insulin resistance as well as scientific syndromes associated with insulin resistance. Clinical and useful measures of insulin resistance also are included. Despite our incomplete knowledge of the complicated organic mechanisms of insulin motion and insulin resistance, we want to do not forget the dramatic social modifications of the past century with appreciate to physical hobby, weight loss plan, work, and socialisation and sleep patterns. Rapid globalisation, urbanisation and industrialisation have spawned epidemics of obesity, diabetes and their attendant co-morbidities, as bodily state of no activity and dietary imbalance unmask latent predisposing genetic trends.

Alpha-amylase inhibition can treat diabetes mellitus

Abstract: Diabetes mellitus is one amongst the main diseases prevailing worldwide. New therapeutic approaches are being investigated to regulate postprandrial glucose levels due to severe side-effects of commercially available anti-diabetic medications. Alpha-amylase is responsible for postprandial glucose levels therefore, different plant extracts with alpha-amylase inhibitory activity are being investigated that might decrease postprandial blood glucose levels, thus being an interesting and novel therapeutic target for diabetes mellitus treatment. A possible strategy to block dietary carbohydrate absorption is to use natural resources as carbohydrate digestive enzyme inhibitors as they have fewer side effects than synthetic drugs. Thus, in this review alpha-amylase inhibitory activity of medicinal plants and their phytochemical compounds are explored that might be helpful within the treatment of diabetes mellitus.

Biomarkers Role in Breast Cancer Treatment-A Review

Abstract: Cancer begins as a nearby sickness, yet it can metastasize to the lymph hubs and far off organs. At essential finding, prognostic markers are utilized to survey whether the move to systemic illness is probably going to have happened. The overall model of metastasis mirrors this view - it recommends that metastatic limit is a late, obtained occasion in tumourigenesis. Others have proposed the possibility that breast tumour is inherently a systemic sickness. New atomic advancements, for example, DNA microarrays, bolster metastatic limit may be an innate component of breast tumours. This information has critical ramifications for visualization predicition and our comprehension of metastasis.

OBESITY: An Overview

Abstract: Body condition in which the muscle to fat quotients gathers in such a sum, to the point that it influences the body in a damaging manner, that condition is commonnly known as heftiness. In the event that this condition is not controlled in a standard manner then it can prompt short future. At first it was accepted that corpulence wins just in high salary and created nations yet another study proposes that it is presently basic in low pay nations and creating nations. Development of the fat tissue and instinctive fat stations the danger of stoutness expands some complex circumstance, for example, insulin resistance, sort 2 diabetes, atherosclerosis, steatohepatitis, and cardio- and cerebro-vascular illnesses.

Review on Cancer

Abstract: Cancer is the abnormal cell growth which has an ability to invade and eventually spread to other parts of the body. The term cancer was given by a Greek Physician Hippocrates (460-370 BC). In the earlier days Non- Ulcer forming and ulcer forming tumors were called carcinoma and carcinos. Cells that grow abnormally cause cancer. Many people die due to cancer. It is the second leading disease in United States that cause death. Women are mostly affected by cancer. In the world one half of men suffer from cancer but one third of women suffer from cancer. Hence women are considered as the victims of cancer.