Revista Da Sociedade Brasileira De Medicina Tropical 

About: Revista Da Sociedade Brasileira De Medicina Tropical is an academic journal published by Brazilian Society of Tropical Medicine. The journal publishes majorly in the area(s): Population & Medicine. It has an ISSN identifier of 0037-8682. It is also open access. Over the lifetime, 5600 publications have been published receiving 72626 citations.

Leishmaniose tegumentar americana

Abstract: American cutaneous leishmaniasis is endemic in widespread areas of Latin America. The causative agents include L. (V.) braziliensis, L. (L.) mexicana, L. (V.) panamensis, and related species. The spectrum of disease includes single, localized, cutaneous ulcers, diffuse cutaneous leishmaniasis, and mucosal disease. The main reservoirs for L. (V.) braziliensis and other Leishmania (Vianna) spp. are small forest rodents. The vectors are ground-dwelling or arboreal Lutzomyia sandflies, which are abundant in the forest. Disease is most common in persons working at the edge of the forest and among rural settlers. The incubation period of cutaneous leishmaniasis varies from two weeks to several months. A wide variety of skin manifestations ranging from small, dry, crusted lesions to large, deep, mutilating ulcers may be seen. Ulcerative lesions are usually shallow and circular with well-defined, raised borders and a bed of granulation tissue. In L. (V.) braziliensis infection, regional lymphadenopathy often precedes the development of cutaneous lesions by one to 12 weeks. A definite diagnosis depends on the identification of amastigotes in tissue or promastigotes in culture. Antileishmanial antibodies are present in the serum of some patients with cutaneous leishmaniasis as detected by ELISA, immunofluorescent assays, direct agglutination tests or other assays, but the titers are usually low. The leishmanin skin test result usually becomes positive during the course of the disease. For treatment two pentavalent antimony-containing drugs are used: stibogluconate sodium, and meglumine antimoniate (Glucantime). Amphotericin B deoxycholate is an alternative for persons who fail to respond to pentavalent antimony. Immunoprophylaxis and immunotherapy are promising new approaches to prevention and treatment.

AIDS e infecção pelo HIV no Brasil: uma epidemia multifacetada

Abstract: The HIV/AIDS epidemic is a dynamic unstable global phenomenon, constituting a veritable mosaic of regional sub-epidemics. As a consequence of the deep inequalities that exist in Brazilian society, the spread of HIV infection has revealed an epidemic of multiple dimensions undergoing extensive epidemiological transformations. Initially restricted to large urban centers and markedly masculine, the HIV/AIDS epidemic is currently characterized by heterosexualization, feminization, interiorization and pauperization. The evolution of the profile of AIDS in Brazil is above all due to the geographical diffusion of the disease from large urban centers towards medium and small municipalities in the interior, to the increase in heterosexual transmission and the persistent growth of cases among injecting drug users. The increase in transmission through heterosexual contact has resulted in substantial growth of cases among women, which has been pointed out as the most important characteristic of the epidemic's current dynamic in Brazil.

Guideliness in paracoccidioidomycosis

Abstract: 1.Departamento de Molestias Infecciosas e Parasitarias da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, SP. 2. Departamento de Saude Comunitaria da Universidade Federal do Parana, Curitiba, PR. 3. Departamento de Doencas Tropicais e Diagnostico por Imagem da Faculdade de Medicina Botucatu da Universidade Estadual de Sao Paulo, Sao Paulo, SP. 4. Departamento de Medicina da Escola Paulista de Medicina, Sao Paulo, SP. 5. Departamento de Clinica Medica da Faculdade Ciencias Medicas da Universidade Estadual de Campinas, Campinas, SP. *Consultores do Consenso em Paracoccidioidomicose: Adriana Kono, Antonia Terezinha Tresoldi, Bodo Wanke, Carlos Roberto Carvalho, Gil Benard, Luiz Carlos Severo, Marcelo Simao Ferreira, Mario Leon Silva Vergara, Roberto Martinez, Rogerio Jesus Pedro, Silvio Alencar Marques, Zarifa Khoury. Patrocinio sem conflito de interesse com entidades privadas: Sociedade Brasileira de Medicina Tropical, Sociedade Brasileira de Infectologia e Sociedade Paulista de Infectologia. Endereco para correspondencia: Dra. Maria Aparecida Shikanai-Yasuda. Laboratorio de Imunologia. Av. Eneias de Carvalho Aguiar 500, Terreo, Sala 4, 05403-000 Sao Paulo, Brasil. Tel: 11 3066-7048, Fax:11 3069-7507 e-mail: lim48imuno@yahoo.com.br Recebido para publicacao em 20/5/2006 Aceito em 2/6/2006 1. INTRODUCAO

Paracoccidioidomycosis: a recently proposed classification of its clinical forms

Abstract: Many attempts have been made to define the cli­ nical forms of human paracoccidioidomycosis15. Several classifications are based on different para­ meters of the disease such as entry route (tegumentary or pulmorary15); presence or absence of signs and/or symptoms (infection vs. disease2 14); organs involved (lymphatic form; pulmonary form15); presen­ ce or absence of activity (active; latent12); type of evolution (progressive; regressive1 2 20); duration of the disease (acute; subacute; chronic4); clinical course (localised; systemic4 26); type of infection (primary; endogenous or exogenous reinfection19); presence or absence of sequelae (cor pulmonale; Addison’s disea­ se12); pathological anatomy (isolated organic form; pseudotumoral forms22) and immunohistological res­ ponse (polar forms21). This variety of criteria is an indication of the partial acceptance of most of them. This is comprehen­ sible since we still do not know where the fungus comes from and how it invades the human host, making difficult the evaluation of the early phases of the disease. In the “ Segundo Encontro sobre Paracoccidioidomicose” held in Botucatu, Brazil, in 1983, a commi­ ttee of experts* was nominated with the objective of proposing a classification of clinical forms of the disease. A questionnaire was circulated among the members and the committee reconvened at the Inter­

Consenso em paracoccidioidomicose

Abstract: Universidade de Sao Paulo Faculdade de Medicina Departamento de Molestias Infecciosas e Parasitarias