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JournalISSN: 2214-1804

Sensing and bio-sensing research 

Elsevier BV
About: Sensing and bio-sensing research is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Biosensor & Photonic-crystal fiber. It has an ISSN identifier of 2214-1804. It is also open access. Over the lifetime, 534 publications have been published receiving 9399 citations.

Papers published on a yearly basis

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Journal ArticleDOI
TL;DR: The range of recent studies about covalent and noncovalent modes for conjugation of antibodies to the particle surface that aim to advance gold nanoparticle treatments and diagnostics toward the clinic are reviewed.
Abstract: The unique properties of gold nanoparticles, their rich surface chemistry, and low toxicity as well as easy methods of synthesis have promoted conjugation of the particles with numerous biomolecules for site-specific delivery. Gold nanoparticles have multiple applications including photoablation, diagnostic imaging, radiosensitization, vaccine development, antioxidant, and multifunctional drug-delivery vehicles. These applications require an increasingly complex level of surface decoration in order to achieve efficacy, and limit off-target toxicity. This review will discuss the chemical and physical approaches commonly utilized in relation to surface decoration and the powerful system used to indicate success of the conjugation. Finally, we review the range of recent studies about covalent and noncovalent modes for conjugation of antibodies to the particle surface that aim to advance gold nanoparticle treatments and diagnostics toward the clinic.

362 citations

Journal ArticleDOI
TL;DR: The scope of different wearable technologies for animals, nano biosensors and advanced molecular biology diagnostic techniques for the detection of various infectious diseases of cattle are discussed, along with the efforts to enlist and compare these technologies with respect to their drawbacks and advantages in the domain of animal health management.
Abstract: Biosensors, as an application for animal health management, are an emerging market that is quickly gaining recognition in the global market. Globally, a number of sensors being produced for animal health management are at various stages of commercialization. Some technologies for producing an accurate health status and disease diagnosis are applicable only for humans, with few modifications or testing in animal models. Now, these innovative technologies are being considered for their future use in livestock development and welfare. Precision livestock farming techniques, which include a wide span of technologies, are being applied, along with advanced technologies like microfluidics, sound analyzers, image-detection techniques, sweat and salivary sensing, serodiagnosis, and others. However, there is a need to integrate all the available sensors and create an efficient online monitoring system so that animal health status can be monitored in real time, without delay. This review paper discusses the scope of different wearable technologies for animals, nano biosensors and advanced molecular biology diagnostic techniques for the detection of various infectious diseases of cattle, along with the efforts to enlist and compare these technologies with respect to their drawbacks and advantages in the domain of animal health management. The paper considers all recent developments in the field of biosensors and their applications for animal health to provide insight regarding the appropriate approach to be used in the future of enhanced animal welfare.

271 citations

Journal ArticleDOI
TL;DR: In this article, the authors focus on some recent strategies for DNA probes immobilization on the surface of electrochemical transducers such as adsorption, covalent bonding and Avidin/Streptavidin-Biotin interaction on the electrode surface for specific interaction with its complementary DNA target.
Abstract: In recent years, electrochemical deoxyribonucleic acid (DNA) sensor has recently emerged as promising alternative clinical diagnostic devices especially for infectious disease by exploiting DNA recognition events and converting them into an electrochemical signal This is because the existing DNA diagnostic method possesses certain drawbacks such as time-consuming, expensive, laborious, low selectivity and sensitivity DNA immobilization strategies and mechanism of electrochemical detection are two the most important aspects that should be considered before developing highly selective and sensitive electrochemical DNA sensor Here, we focus on some recent strategies for DNA probes immobilization on the surface of electrochemical transducer such as adsorption, covalent bonding and Avidin/Streptavidin-Biotin interaction on the electrode surface for specific interaction with its complementary DNA target A numerous approach for DNA hybridization detection based electrochemical technique that frequently used including direct DNA electrochemical detection and label based electrochemical (redox-active indicator, enzyme label and nanoparticles were also discussed in aiming to provide general guide for the design of electrochemical DNA sensor We also discussed the challenges and suggestions to improve the application of electrochemical DNA sensor at point-care setting

198 citations

Journal ArticleDOI
TL;DR: A unique, disposable saliva nano-biosensor is developed enabling noninvasive diagnosis of diabetes through saliva instead of blood and a good correlation of glucose levels in saliva and in blood before and 2 h after glucose intake was observed.
Abstract: Millions of people worldwide live with diabetes and several millions die from it each year. A noninvasive, painless method of glucose testing would highly improve compliance and glucose control while reducing complications and overall disease management costs. To provide accurate, low cost, and continuous glucose monitoring, we have developed a unique, disposable saliva nano-biosensor. More than eight clinical trials on real-time noninvasive salivary glucose monitoring were carried out on two healthy individuals (a 2–3 h-period for each trial, including both regular food and standard glucose beverage intake with more than 35 saliva samples obtained). Excellent clinical accuracy was revealed as compared to the UV Spectrophotometer. By measuring subjects’ salivary glucose and blood glucose in parallel, we found the two generated profiles share the same fluctuation trend but the correlation between them is individual dependent. There is a time lag between the peak glucose values from blood and from saliva. However, the correlation between the two glucose values at fasting is constant for each person enabling noninvasive diagnosis of diabetes through saliva instead of blood. Furthermore, a good correlation of glucose levels in saliva and in blood before and 2 h after glucose intake was observed. Glucose monitoring before and 2 h after meals is usually prescribed by doctors for diabetic patients. Thus, this disposable biosensor will be an alternative for real-time salivary glucose tracking at any time.

167 citations

Journal ArticleDOI
TL;DR: In this paper, a flexible and wearable dry ECG electrodes for monitoring electrocardiogram (ECG) signals, without any skin preparation and use of wet gel, has been developed.
Abstract: Printed, flexible and wearable dry electrodes for monitoring electrocardiogram (ECG) signals, without any skin preparation and use of wet gel, has been developed. Silver (Ag) flake ink was screen printed on a flexible polyethylene terephthalate (PET) substrate to fabricate the dry ECG electrode. Multi-walled carbon nanotube (MWCNT)/polydimethylsiloxane (PDMS) composite, as a conductive polymer, was then deposited on the printed Ag electrode by using a bar coating technique. The performance of the printed electrodes was investigated by testing the MWCNT/PDMS composite conductivity and measuring the electrode-skin impedance for electrode radii varying from 8 mm to 16 mm. It was observed that the dry ECG electrode, with the largest area, demonstrated better performance, in terms of MWCNT/PDMS composite conductivity, ECG signal intensity and correlation when compared to a commercial wet silver/silver chloride (Ag/AgCl) electrode. In addition, the capability of the dry ECG electrodes for monitoring ECG signals in both the relaxed sitting position and while the subject is in motion, was also investigated and the results were compared with a wet Ag/AgCl ECG electrode (T716). While the subject is in motion, the printed dry electrodes were less noisy and were able to better identify the typical ECG characteristics in the signals due to its better conformal contact at the electrode-skin interface. The results obtained demonstrated the feasibility of employing conventional screen printing process for the development of flexible dry ECG electrodes for applications in the biomedical industry.

133 citations

Performance
Metrics
No. of papers from the Journal in previous years
YearPapers
202321
202271
202171
202082
201959
201831