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Showing papers in "Sleep Medicine in 2013"


Journal ArticleDOI
TL;DR: The vast majority of men > or =50 years old initially diagnosed with iRBD in this study eventually developed a parkinsonian disorder/dementia, often after a prolonged interval from onset of iR BD, with the mean interval being 14 years while the range extended to 29 years.

628 citations



Journal ArticleDOI
TL;DR: The use of either a dopamine-receptor agonist or α2δ calcium-channel ligand is recommended as the first-line treatment of RLS/WED for most patients, with the choice of agent dependent on the patient's severity of RLP symptoms, cognitive status, history, and comorbid conditions.

255 citations


Journal ArticleDOI
TL;DR: A U-shaped relationship between habitual sleep duration and hypertension was found at the cross-sectional level among adults and short sleep duration was associated with a higher risk for hypertension even longitudinally.

222 citations


Journal ArticleDOI
TL;DR: The IRBD-SG provides an important platform for developing multinational collaborative studies on RBD such as on environmental risk factors for iRBD, and on controlled active treatment studies for symptomatic and neuroprotective therapy that emerged during the 2011 consensus conference in Marburg, Germany, as described in this report.

198 citations


Journal ArticleDOI
TL;DR: Narcolepsy is associated with a high comorbidity of both medical conditions and psychiatric disorders that need to be addressed when developing a treatment plan.

191 citations


Journal ArticleDOI
TL;DR: Melatonin and clonazepam were each reported to reduce RBD behaviors and injuries and appeared comparably effective in the authors' naturalistic practice experience.

184 citations


Journal ArticleDOI
TL;DR: Significant cross-cultural differences in sleep patterns, sleeping arrangements, and parent-reported sleep problems in preschool-aged children in multiple predominantly Asian and predominantly Caucasian countries are indicated.

183 citations


Journal ArticleDOI
TL;DR: Revised diagnostic criteria for pediatric RLS have been developed, which are intended to improve clinical practice and promote further research.

167 citations


Journal ArticleDOI
TL;DR: The data collected during 3 years following vaccination showed a significantly increased risk for narcolepsy with cataplexy and reduced CSF hypocretin levels in vaccinated children ages 4-19 years the first year after Pandemrix® vaccination, with a minimum incidence of 10 of 100,000 individuals per year.

165 citations


Journal ArticleDOI
TL;DR: Shorter self-reported sleep duration was associated with a higher likelihood of reporting depressive symptoms, suicidal ideation, and overweight or obese status, and a lower likelihood of reported better self-rated health, even after accounting for time spent on Internet use.

Journal ArticleDOI
TL;DR: Despite experimental and orthodontic data supporting the connection between orofacial muscle activity and oropharyngeal development as well as the demonstration of abnormal muscle contraction of upper airway muscles during sleep in patients with SDB, myofunctional therapy rarely is considered in the treatment of pediatric SDB.

Journal ArticleDOI
TL;DR: CPAP therapy could partially suppress systemic inflammation in OSA patients, and substantial differences were present among the various inflammatory markers.

Journal ArticleDOI
TL;DR: Initial efficacy favored the BPT program over the comparison group and suggested that this manualized parent training approach is worthy of further examination of the efficacy within a larger RCT.

Journal ArticleDOI
TL;DR: Poor sleep quality is significantly associated with resistance to treatment in hypertensive women, independent of cardiovascular and psychiatric confounders.

Journal ArticleDOI
TL;DR: PLMS were associated with sudden and significant increases of HR, SBP and DBP in both groups; however, cardiovascular increases were more pronounced in RLS subjects than in healthy subjects.

Journal ArticleDOI
TL;DR: Clinical RBD symptoms, but not subclinical RBD, were associated with the development of dementia in patients with Parkinson's disease.

Journal ArticleDOI
TL;DR: The iButton is an inexpensive, wireless data logger that can be used to obtain a valid measurement of human skin temperature and is a practical alternative to traditional measures of circadian rhythms in sleep/wake research.

Journal ArticleDOI
TL;DR: Neither a prior diagnosis of OSA nor a positive screen for OSA risk was associated with increased 30-day or one-year postoperative mortality and none of the OSA screening tools independently predicted mortality rate up to one year postoperatively.

Journal ArticleDOI
TL;DR: It is extremely important to identify the individuals at risk of sleep loss, since recognition and adequate treatment of their sleep problems may reduce the risk of certain neurologic disorders.

Journal ArticleDOI
TL;DR: Short sleep duration and sleep disturbances are prevalent among Chinese school-aged children and are associated with gender, school grade, co-sleeping, emotional symptoms, conduct problems, and hyperactivity.

Journal ArticleDOI
TL;DR: Different threat simulations and modes of defense seem to play a role during dream-enacted behaviors (e.g., fleeing a disaster during SW/ST, counterattacking a human or animal assault during RBD), paralleling and exacerbating the differences observed between normal dreaming in nonrapid eye movement (NREM) vs rapidEye movement (REM) sleep.

Journal ArticleDOI
TL;DR: It is demonstrated that automated scoring of sleep obtained from a single-channel of forehead EEG results in agreement to majority manual scoring are similar to results obtained from studies of manual interrater agreement.

Journal ArticleDOI
TL;DR: Shorter sleep, SWS, and REMS duration were associated with higher BMI, central adiposity measurements, and cardiovascular risk factors when measured by objective methods.

Journal ArticleDOI
TL;DR: The whole pattern of results confirms that the centrofrontal areas showed an earlier synchronization (i.e., they fall asleep first), which implies a coexistence of wakelike and sleeplike electrical activity during sleep in different cortical areas and implies that the process of progressive brain disconnection from the external world as the authors fall asleep does not necessarily affect primary and higher-order cortices at the same time.

Journal ArticleDOI
TL;DR: Long-term CPAP/NIV adherence at home was extremely high in this group of children followed in a pediatric NIV unit, and this finding may explain the lack of effect of the interface, nocturnal gas exchange, and duration of CPAP-NIV treatment.

Journal ArticleDOI
TL;DR: Sleeping with the light on not only causes shallow sleep and frequent arousals but also has a persistent effect on brain oscillations, especially those implicated in sleep depth and stability, as demonstrated in this study.

Journal ArticleDOI
TL;DR: Longer habitual afternoon napping was associated with a moderate increase for DM risk, independent of several covariates, which suggests that longer nap duration may represent a novel risk factor for DM and higher blood glucose levels.

Journal ArticleDOI
TL;DR: Gradual sleep extension has beneficial effects on adolescents' sleep and is related to changes in some aspects of cognitive performance, especially visuospatial processing, significantly changed in the sleep extension group.

Journal ArticleDOI
TL;DR: It is proposed that hypocretin neurons are centrally involved in motor control during wakefulness and sleep in humans, and that hypocRETin deficiency causes a functional defect in the motor control involved in the development of cataplexy during wakeful and RBD/RSWA/phasic motor activity during REM sleep.