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JournalISSN: 2220-1181

Southern African Journal of Anaesthesia and Analgesia 

Taylor & Francis
About: Southern African Journal of Anaesthesia and Analgesia is an academic journal published by Taylor & Francis. The journal publishes majorly in the area(s): General anaesthesia & Perioperative. It has an ISSN identifier of 2220-1181. It is also open access. Over the lifetime, 1068 publications have been published receiving 3110 citations. The journal is also known as: SAJAA.


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Journal ArticleDOI
IM Moxham1
TL;DR: The arterial pulse is the result of a wave of vascular distention initiated by the impact of the stroke volume ejected into a closed system with every heartbeat.
Abstract: Extracted from text ... REGISTRAR PRIZE 40 Understanding arterial pressure waveforms their relation to the cardiac cycle the difference in waveforms recorded from different body sites The arterial pulse is the result of a wave of vascular distention, initiated by the impact of the stroke volume ejected into a closed system with every heartbeat. The forward-propagating pressure wave has both a fast-moving (10m/sec) and slower (0, 5m/sec) component.5 The wave is reflected back mostly by the arteriole, which provides the majority of peripheral vascular resistance.6 Peak aortic blood flow acceleration produces the initial rise of the pressure pulse, whereas the ejection ..

39 citations

Journal ArticleDOI
TL;DR: Melatonin (3 mg) can be successfully used as premedication for laparoscopic cholecystectomy, especially for day case surgery, and a better recovery profile as assessed by sedation and memory.
Abstract: Background: There are only a few studies involving the use of melatonin for premedication for anaesthesia. The goal of our study was to compare the effects of melatonin and midazolam administered a...

36 citations

Journal ArticleDOI
TL;DR: The incidence of postoperative pain is high as expected at a Western Cape referral hospital, and at least one low-cost analgesic modality is currently underutilised.
Abstract: Background: Postoperative pain is poorly studied in developing countries. At a Western Cape referral hospital, it was aimed to determine the incidence of acute postoperative pain, to identify populations associated with a higher risk thereof (in order to guide resource allocation) and to investigate whether inexpensive analgesic modalities are currently utilised maximally.Methods: Patients completed visual analogue scales 24 h after surgery for pain immediately after surgery, maximum pain since surgery and current pain. The incidence of moderate or severe pain and median pain scores were calculated for each scale and for different patient populations. Post hoc logistic regression was performed. Morphine prescriptions were compared with the actual administration thereof.Results: Of 1 231 patients, 62% indicated their maximum pain as moderate or severe. Procedures with the highest incidences were caesarean section and lower limb orthopaedic surgery (> 80%). Younger age, female gender, emergency surgery, and...

35 citations

Journal ArticleDOI
TL;DR: The purpose of this review is to discuss dexmedetomidine in terms of its pharmacokinetics and pharmacodynamics, and to focus on its various clinical applications.
Abstract: Dexmedetomidine is a highly selective and potent alpha2-adrenoreceptor (AR) agonist offering dosedependent sedation, anxiolysis and analgesia. It is a relatively new drug, approved for sedation for up to 24 hours in mechanically ventilated post-cardiac surgery patients. Yet, because of its unique drug profile, it has been increasingly studied and used in various clinical settings, albeit off label, with promising results. The purpose of this review is to discuss dexmedetomidine in terms of its pharmacokinetics and pharmacodynamics, and to focus on its various clinical applications. A PubMed search, using the keyword “dexmedetomidine”, identified approximately 1,000 articles, the earliest being animal studies published in 1988.

34 citations

Journal ArticleDOI
TL;DR: The reasons for this chronic post-surgical pain are discussed in this presentation, as are possible preventative strategies.
Abstract: Why some patients develop chronic pain after an acutely painful event remains an enigma. For example, over 90% of the population will experience acute back pain at some time in their lives. In most cases this resolves but, in a few, it does not, even though these patinets have radiologic pathology similar to those in whom the pain does improve. Similarly, there are few people who escape the hands of the surgeon. What is becoming increasingly apparent is that those who do experience the sharp end of the scalpel frequently experience persistent pain as a result of the damage caused by this instrument. The reasons for this chronic post-surgical pain are discussed in this presentation, as are possible preventative strategies.

27 citations

Performance
Metrics
No. of papers from the Journal in previous years
YearPapers
20235
202238
202130
202080
201937
201853