Showing papers in "Southern Medical Journal in 1974"
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92 citations
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TL;DR: It is suggested that Negro stratum corneum is a more effective barrier to irritants than Caucasian skin, and what accounts for this superiority is not known.
Abstract: :The belief that Negro skin resists irritants better than Caucasian skin was tested by quantitative patch test exposure to dinitrochlorobenzene (DNCB) in acetone. With concentration as the variable, the minimal perceptible erythema (MPE) dose of DNCB was determined on the backs of Caucasians
76 citations
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69 citations
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35 citations
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TL;DR: In preterm infants, patient-triggered ventilation modalities result in lower work of breathing than intermittent Mandatory ventilation, while the assist control mode is also associated with lower pressure-time product of the diaphragm compared with synchronized intermittent mandatory ventilation.
Abstract: 430 www.pccmjournal.org May 2020 • Volume 21 • Number 5 Objectives: To compare the imposed work of breathing by means of pressure-time product of the diaphragm in newborn infants receiving different modes of mechanical ventilation. Design: Prospective observational crossover study. Setting: Tertiary care neonatal unit. Patients: Forty preterm newborns (gestational age ≤ 37 wk) in the phase of weaning from mechanical ventilation. Interventions: Participants were ventilated in assist control, synchronized intermittent mandatory ventilation, and intermittent mandatory ventilation mode, in a crossover manner. The combination synchronized intermittent mandatory ventilation–pressure support (SIMV–PS) at 50% (SIMV–PS50) and 75% (SIMV–PS75) of the difference between peak inflating and positive end-expiratory pressure, was also applied in a subset of infants (n = 11). Each mode was maintained for 30 minutes. Transdiaphragmatic pressure was obtained by digital subtraction of esophageal from gastric pressure (both measured using a dual pressure-tipped catheter), and pressure-time product of the diaphragm was computed by integration of transdiaphragmatic pressure over inspiratory time. Measurements and Main Results: The pressure-time product of the diaphragm was 224.2 ± 112.8 in the intermittent mandatory ventilation mode, 165.8 ± 58.8 in the synchronized intermittent mandatory ventilation mode, and 125.5 ± 61.8 cm H2O × s × min–1 in the assist control mode; all values were significantly different to each other (p < 0.0001). The pressure-time product of the diaphragm difference between assist control and intermittent mandatory ventilation, and assist control and synchronized intermittent mandatory ventilation was negatively related to postmenstrual age (regression coefficient, –0.365; p = 0.020 and –0.341; p = 0.031, respectively). In the SIMV–PS subcohort, the pressure-time product of the diaphragm was significantly higher in the intermittent mandatory ventilation mode as compared with assist control (p < 0.0001) or SIMV–PS75 (p = 0.0027), and in the synchronized intermittent mandatory ventilation mode as compared with assist control (p = 0.0301). Conclusions: In preterm infants, patient-triggered ventilation modalities result in lower work of breathing than intermittent mandatory ventilation, while the assist control mode is also associated with lower pressure-time product of the diaphragm compared with synchronized intermittent mandatory ventilation. The difference in the imposed diaphragmatic workload between these ventilation modalities was inversely related to postmenstrual age, implying that less mature infants benefit more from assist control-based ventilation strategies. (Pediatr Crit Care Med 2020; 21:430–436)
32 citations
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31 citations
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28 citations
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28 citations
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TL;DR: A retrospective analysis of 158 transrectal prostatic needle biopsy examinations done in 140 patients from Jan 1, 1968, through April 30, 1972, showed 62 complications in 51 biopsies.
Abstract: Abstract: A retrospective analysis of 158 transrectal prostatic needle biopsy examinations done in 140 patients from Jan 1, 1968, through April 30, 1972, showed 62 complications in 51 biopsies. Fourteen major complications occurred in 11 patients. Fever developed in 41 (26%) of the patients. A review of the literature dealing with complications of prostatic biopsy is given. The following recommendations are made: (1) the use of the perineal approach whenever possible; (2) the use of prophylactic antimicrobials; (3) hospitalization for prostatic biopsy examination.
25 citations
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TL;DR: For patients with predominantly comedonal acne or in those with inflammatory acne who for one reason or another cannot receive antibiotics, tretinoin alone is used and the majority of patients have both inflammatory and comedonal lesions.
Abstract: The intent of this report is to summarize our experience in treating acne with tretinoin, antibiotics, and the combination of both agents. For patients with predominantly comedonal acne or in those with inflammatory acne who for one reason or another cannot receive antibiotics, tretinoin alone is used. The majority of patients have both inflammatory and comedonal lesions. These patients are treated with combination of tretinoin plus systemic antibiotics. Full doses are employed for three weeks and then halved. Once inflammatory lesions are suppressed, the antibiotic is withdrawn slowly and treatment continued with tretinoin alone. Occasionally, reintroduction of antibiotics is required. Continuance of tretinoin allows the majority of patients to be withdrawn from antibiotics without relapse. Once antibiotics have been stopped totally, tretinoin usage is titrated until maintenance dose is achieved. Severe inflammatory acne conglobata requires full doses of antibiotics plus tretinoin for a longer period before suppression of inflammatory lesions can be achieved.
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TL;DR: Review of 66 triple arthrodeses in 47 children with a minimal follow-up of two years provides a study of contemporary experience with this surgical procedure, finding over 90% of patients had no or negligible pain; 79% considered their feet to be satisfactory in appearance; and most wore regular or mismatched shoes.
Abstract: :Review of 66 triple arthrodeses in 47 children (average age at operation, 12.1 years) with a minimal follow-up of two years provides a study of contemporary experience with this surgical procedure. Over 90% of patients had no or negligible pain; 79% considered their feet to be satisfactory
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TL;DR: In this paper, the carotid artery reconstructive procedures were performed in 34 patients with concomitant atherosclerotic arterial disease which had been diagnosed during the first operation.
Abstract: :Thirty-four neurologically asymptomatic patients had 42 prophylactic carotid artery reconstructive procedures before another major operation. Thirty-one of the 34 planned second operations in these patients were for management of concomitant atherosclerotic arterial disease which had produc
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TL;DR: Three cases of paraplegic patients with Bacteroides bccteremia from decubitus ulers are reported and each patient was treated initially and unsuccessfully with antibiotics normally useful for aerobic gram-neg.
Abstract: Three cases of paraplegic patients with Bacteroides bccteremia from decubitus ulers are reported. Each patient was suspected of having another organism and another source of infection. Each patient was treated initially and unsuccessfully with antibiotics normally useful for aerobic gram-neg
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TL;DR: Clinical observations confirm an earlier preliminary report of 26 patients, describing the therapeutic response of nocturnal leg cramps and other types of muscle spasms to adequate doses of d, alphatocopheryl acetate.
Abstract: The following clinical observations confirm an earlier preliminary report of 26 patients, describing the therapeutic response of nocturnal leg cramps and other types of muscle spasms to adequate doses of d, alphatocopheryl acetate. In a total of 125 documented cases of nocturnal cramps only
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TL;DR: A review of the literature pertaining to anesthesia for the obese surgical patient is presented, and data are provided from a retrospective study of 59 morbidly obese patients evaluated for anesthesia for surgical procedures at The University of Texas Medical Branch Hospitals.
Abstract: :A review of the literature pertaining to anesthesia for the obese surgical patient is presented, and data are provided from a retrospective study of 59 morbidly obese patients evaluated for anesthesia for surgical procedures at The University of Texas Medical Branch Hospitals. The majority
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TL;DR: A complete temporary sciatic nerve interruption occurred after a posterior fracture-dislocation of the hip joint and ectopic new bone formation accounted for the interruption in nerve conduction.
Abstract: :A complete temporary sciatic nerve interruption occurred after a posterior fracture-dislocation of the hip joint. Ectopic new bone formation accounted for the interruption in nerve conduction. Neurolysis was done two months after the initial injury. Partial recovery of motor power and sensa
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TL;DR: When endometriosis of the colon is of a degree sufficient to cause symptoms, partial colectomy should be done; oophorectomy only, without resection, is not recommended.
Abstract: Reviewed are the clinical, radiologie, operative and pathologic findings and the results in 14 women (ages 31 to 51 years) requiring partial colectomy for endometriosis. All had symptoms related to the lesion of the colon; eight had gynecologic symptoms. In only four instances did the physical examination reveal a palpable mass. Most important in making the preoperative diagnosis is radiographie examination of the colon (barium enema). In common localized endometrioma, features are those of an eccentric intramural, submucosal lesion with transverse ridging. More extensive endometriosis is more difficult to differentiate from carcinoma by radiographie means. Operative diagnosis, which was less accurate than radiologie diagnosis, should be suggested by uninvolved mucosa on examination of the unopened colon and frozen section diagnosis of endometriosis on an implant. When endometriosis of the colon is of a degree sufficient to cause symptoms, partial colectomy should be done; oophorectomy only, without resection, is not recommended.